Annotations: 5ZON

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00459	e5zonA1	A: a+b two layers	X: a+b domain in carbohydrate phosphatases (From Topology)	H: a+b domain in carbohydrate phosphatases (From Topology)	T: a+b domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
A	PF00459	e5zonA2	A: a/b three-layered sandwiches	X: Rossmann-like domain in carbohydrate phosphatases (From Homology)	H: Rossmann-like domain in carbohydrate phosphatases	T: Rossmann-like domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
B	PF00459	e5zonB2	A: a+b two layers	X: a+b domain in carbohydrate phosphatases (From Topology)	H: a+b domain in carbohydrate phosphatases (From Topology)	T: a+b domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
B	PF00459	e5zonB1	A: a/b three-layered sandwiches	X: Rossmann-like domain in carbohydrate phosphatases (From Homology)	H: Rossmann-like domain in carbohydrate phosphatases	T: Rossmann-like domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
C	PF00459	e5zonC1	A: a+b two layers	X: a+b domain in carbohydrate phosphatases (From Topology)	H: a+b domain in carbohydrate phosphatases (From Topology)	T: a+b domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
C	PF00459	e5zonC2	A: a/b three-layered sandwiches	X: Rossmann-like domain in carbohydrate phosphatases (From Homology)	H: Rossmann-like domain in carbohydrate phosphatases	T: Rossmann-like domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
D	PF00459	e5zonD2	A: a+b two layers	X: a+b domain in carbohydrate phosphatases (From Topology)	H: a+b domain in carbohydrate phosphatases (From Topology)	T: a+b domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)
D	PF00459	e5zonD1	A: a/b three-layered sandwiches	X: Rossmann-like domain in carbohydrate phosphatases (From Homology)	H: Rossmann-like domain in carbohydrate phosphatases	T: Rossmann-like domain in carbohydrate phosphatases	F: PF00459	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.540.10	Alpha Beta	2-Layer Sandwich	Fructose-1,6-Bisphosphatase	Chain A, domain 1	CATH (4.3.0)
B	3.30.540.10	Alpha Beta	2-Layer Sandwich	Fructose-1,6-Bisphosphatase	Chain A, domain 1	CATH (4.3.0)
C	3.30.540.10	Alpha Beta	2-Layer Sandwich	Fructose-1,6-Bisphosphatase	Chain A, domain 1	CATH (4.3.0)
D	3.30.540.10	Alpha Beta	2-Layer Sandwich	Fructose-1,6-Bisphosphatase	Chain A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00459	Inositol monophosphatase family (Inositol_P)	Inositol monophosphatase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Histidinol-phosphatase	phosphoric ester hydrolase activity histidinol-phosphatase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity catalytic activity inositol monophosphate 1-phosphatase activity inositol monophosphate phosphatase activity inositol phosphate phosphatase activity cation binding ion binding binding metal ion binding small molecule binding	carbohydrate derivative biosynthetic process mycothiol biosynthetic process glycosyl compound metabolic process glycosyl compound biosynthetic process cellular biosynthetic process cellular metabolic process glycoside metabolic process carbohydrate derivative metabolic process mycothiol metabolic process glycoside biosynthetic process sulfur compound biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process carbohydrate derivative biosynthetic process mycothiol biosynthetic process glycosyl compound metabolic process glycosyl compound biosynthetic process cellular biosynthetic process cellular metabolic process glycoside metabolic process carbohydrate derivative metabolic process mycothiol metabolic process glycoside biosynthetic process sulfur compound biosynthetic process organic substance metabolic process biosynthetic process organic substance biosynthetic process sulfur compound metabolic process metabolic process cellular process organonitrogen compound metabolic process small molecule biosynthetic process oxoacid metabolic process organonitrogen compound biosynthetic process carboxylic acid metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process small molecule metabolic process histidine metabolic process histidine biosynthetic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cell periphery plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR011809	Histidinol-phosphate phosphatase, putative, inositol monophosphatase	Family
A, B, C, D	IPR020583	Inositol monophosphatase, metal-binding site	Binding Site
A, B, C, D	IPR000760	Inositol monophosphatase-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.