Annotations: 5Z1F

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5z1fa2	Alpha and beta proteins (a+b)	Ferredoxin-like	Cytosolic domain of OSCA channel-like	Cytosolic domain of OSCA channels	Mechanosensitive channel AtOSCA3.1	Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)
A	d5z1fa1	Membrane and cell surface proteins and peptides	Anoctamin (TMEM16)-like	Anoctamin (TMEM16)-like	Hyperosmolality-gated calcium-permeable (OSCA) channel-like	Mechanosensitive channel AtOSCA3.1	Mouse-ear cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF14703	Cytosolic domain of 10TM putative phosphate transporter (PHM7_cyt)	Cytosolic domain of 10TM putative phosphate transporter	PHM7_cyt is the predicted cytosolic domain of integral membrane proteins, such as yeast PHM7 and TM63A_HUMAN TRANSMEMBRANE PROTEIN 63A, SwissProt:O94886. This domain usually precedes the 7TM region, Pfam:PF02714, and follows a RSN1_TM, Pfam:PF13967. ...	PHM7_cyt is the predicted cytosolic domain of integral membrane proteins, such as yeast PHM7 and TM63A_HUMAN TRANSMEMBRANE PROTEIN 63A, SwissProt:O94886. This domain usually precedes the 7TM region, Pfam:PF02714, and follows a RSN1_TM, Pfam:PF13967. Fold recognition programs consistently and with high significance predict this domain to be distantly homologous to RNA binding proteins from the RRM clan.	Domain
A, B	PF13967	Late exocytosis, associated with Golgi transport (RSN1_TM)	Late exocytosis, associated with Golgi transport	-	Family
A, B	PF02714	Calcium-dependent channel, 7TM region, putative phosphate (RSN1_7TM)	Calcium-dependent channel, 7TM region, putative phosphate	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	CSC1-like protein ERD4	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding monoatomic cation transmembrane transporter activity calcium-activated cation channel activity gated channel activity monoatomic ion channel activity monoatomic ion-gated channel activity ligand-gated channel activity ligand-gated monoatomic ion channel activity monoatomic cation channel activity passive transmembrane transporter activity RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding monoatomic cation transmembrane transporter activity calcium-activated cation channel activity gated channel activity monoatomic ion channel activity monoatomic ion-gated channel activity ligand-gated channel activity ligand-gated monoatomic ion channel activity monoatomic cation channel activity passive transmembrane transporter activity channel activity monoatomic ion transmembrane transporter activity transporter activity ligand-gated monoatomic cation channel activity transmembrane transporter activity	-	cell periphery plasma membrane membrane cellular anatomical entity cell-cell junction symplast anchoring junction cell junction plasmodesma membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle plant-type vacuole cell periphery plasma membrane membrane cellular anatomical entity cell-cell junction symplast anchoring junction cell junction plasmodesma membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle plant-type vacuole vacuole cytoplasm intracellular membrane-bounded organelle plastid chloroplast envelope organelle envelope plastid envelope chloroplast nucleus

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR032880	CSC1/OSCA1-like, N-terminal transmembrane domain	Domain
A, B	IPR027815	CSC1/OSCA1-like, cytosolic domain	Domain
A, B	IPR045122	Calcium permeable stress-gated cation channel 1-like	Family
A, B	IPR003864	CSC1/OSCA1-like, 7TM region	Domain

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B	OPM	Transmembrane	Alpha-helical polytopic	Calcium-activated chloride channel	Mechanosensitive OSCA channels

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Channels: Mechanosensitive	Hyperosmolality-gated calcium-permeable channel (OSCA) 1.1

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.