5YX4

Isoliquiritigenin-complexed Chalcone isomerase (S189A) from the Antarctic vascular plant Deschampsia Antarctica (DaCHI1)

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5yx4a1	Alpha and beta proteins (a+b)	Chalcone isomerase	Chalcone isomerase	automated matches	automated matches	Antarctic hair grass (Deschampsia antarctica ) [TaxId: 159298 ],	SCOPe (2.08)
A	d5yx4a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Antarctic hair grass (Deschampsia antarctica ) [TaxId: 159298 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cytochrome P460/chalcone isomerase-like	8079482	3000788	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02431	e5yx4A1	A: a+b two layers	X: Chalcone isomerase (From Topology)	H: Chalcone isomerase (From Topology)	T: Chalcone isomerase	F: PF02431	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF02431	Chalcone-flavanone isomerase (Chalcone)	Chalcone-flavanone isomerase	Chalcone-flavanone isomerase is a plant enzyme responsible for the isomerisation of chalcone to naringenin, 4',5,7-trihydroxyflavanone, a key step in the biosynthesis of flavonoids.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Chalcone-flavonone isomerase family protein	intramolecular lyase activity isomerase activity chalcone isomerase activity catalytic activity	flavonoid metabolic process organic substance metabolic process flavonoid biosynthetic process biosynthetic process organic substance biosynthetic process metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR016087	Chalcone isomerase	Domain
A	IPR016088	Chalcone isomerase, 3-layer sandwich	Homologous Superfamily
A	IPR044164	Chalcone--flavonone isomerase	Family
A	IPR016089	Chalcone isomerase, orthogonal bundle domain superfamily	Homologous Superfamily
A	IPR036298	Chalcone isomerase superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.