Annotations: 5Y6Q

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5y6qa2	All alpha proteins	CO dehydrogenase ISP C-domain like	CO dehydrogenase ISP C-domain like	automated matches	automated matches	(Methylobacillus sp. KY4400 ) [TaxId: 194289 ],	SCOPe (2.08)
A	d5y6qa1	Alpha and beta proteins (a+b)	beta-Grasp (ubiquitin-like)	2Fe-2S ferredoxin-like	automated matches	automated matches	(Methylobacillus sp. KY4400 ) [TaxId: 194289 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Fer2_2	e5y6qA2	A: alpha bundles	X: CO dehydrogenase ISP C-domain like (From Topology)	H: CO dehydrogenase ISP C-domain like (From Topology)	T: CO dehydrogenase ISP C-domain like	F: Fer2_2	ECOD (1.6)
A	Fer2_3	e5y6qA1	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Ubiquitin-like	F: Fer2_3	ECOD (1.6)
B	CO_deh_flav_C	e5y6qB3	A: a+b two layers	X: FAD-linked reductases, C-terminal domain-like	H: SufE/NifU (From Topology)	T: SufE/NifU	F: CO_deh_flav_C	ECOD (1.6)
B	FAD_binding_5	e5y6qB1	A: a+b complex topology	X: FAD-binding domain-like	H: FAD-binding domain (From Topology)	T: FAD-binding domain	F: FAD_binding_5	ECOD (1.6)
B	YagS_Fe_S_bind	e5y6qB2	A: few secondary structure elements	X: Fe-S cluster binding domain in some xanthine oxidase family enzymes (From Topology)	H: Fe-S cluster binding domain in some xanthine oxidase family enzymes (From Topology)	T: Fe-S cluster binding domain in some xanthine oxidase family enzymes	F: YagS_Fe_S_bind	ECOD (1.6)
C	Ald_Xan_dh_C2	e5y6qC2	A: a+b two layers	X: MocoBD/DmpA-related (From Homology)	H: MocoBD/DmpA-related	T: Molybdenum cofactor-binding domain	F: Ald_Xan_dh_C2	ECOD (1.6)
C	Ald_Xan_dh_C	e5y6qC1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: CO dehydrogenase molybdoprotein N-domain-like	F: Ald_Xan_dh_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.20.30	Alpha Beta	Roll	Ubiquitin-like (UB roll)	Beta-grasp domain	CATH (4.3.0)
A	1.10.150.120	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
B	3.30.390.50	Alpha Beta	2-Layer Sandwich	Enolase-like	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01799	[2Fe-2S] binding domain (Fer2_2)	[2Fe-2S] binding domain	-	Domain
A	PF00111	2Fe-2S iron-sulfur cluster binding domain (Fer2)	2Fe-2S iron-sulfur cluster binding domain	-	Domain
B	PF00941	FAD binding domain in molybdopterin dehydrogenase (FAD_binding_5)	FAD binding domain in molybdopterin dehydrogenase	-	Family
B	PF03450	CO dehydrogenase flavoprotein C-terminal domain (CO_deh_flav_C)	CO dehydrogenase flavoprotein C-terminal domain	-	Domain
C	PF01315	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain (Ald_Xan_dh_C)	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	Domain
C	PF20256	Molybdopterin cofactor-binding domain (MoCoBD_2)	Molybdopterin cofactor-binding domain	-	Domain
C	PF02738	Molybdopterin cofactor-binding domain (MoCoBD_1)	Molybdopterin cofactor-binding domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Aldehyde oxidase small subunit	oxidoreductase activity catalytic activity iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding binding metal cluster binding small molecule binding cation binding ion binding metal ion binding	-	-
B	Aldehyde oxidase medium subunit	oxidoreductase activity catalytic activity FAD binding flavin adenine dinucleotide binding binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding nucleotide binding heterocyclic compound binding small molecule binding	-	-
C	Aldehyde oxidase large subunit	oxidoreductase activity catalytic activity cation binding transition metal ion binding iron ion binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002888	[2Fe-2S]-binding	Domain
A	IPR036010	2Fe-2S ferredoxin-like superfamily	Homologous Superfamily
A	IPR001041	2Fe-2S ferredoxin-type iron-sulfur binding domain	Domain
A	IPR036884	[2Fe-2S]-binding domain superfamily	Homologous Superfamily
A	IPR012675	Beta-grasp domain superfamily	Homologous Superfamily
A	IPR006058	2Fe-2S ferredoxin, iron-sulphur binding site	Binding Site
B	IPR016167	FAD-binding, type PCMH, subdomain 1	Homologous Superfamily
B	IPR036683	CO dehydrogenase flavoprotein, C-terminal domain superfamily	Homologous Superfamily
B	IPR036318	FAD-binding, type PCMH-like superfamily	Homologous Superfamily
B	IPR016169	FAD-binding, type PCMH, subdomain 2	Homologous Superfamily
B	IPR016166	FAD-binding domain, PCMH-type	Domain
B	IPR005107	CO dehydrogenase flavoprotein, C-terminal	Domain
B	IPR002346	Molybdopterin dehydrogenase, FAD-binding	Domain
C	IPR046867	Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain	Domain
C	IPR000674	Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead	Domain
C	IPR016208	Aldehyde oxidase/xanthine dehydrogenase-like	Family
C	IPR036856	Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily	Homologous Superfamily
C	IPR037165	Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily	Homologous Superfamily
C	IPR008274	Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.