5XOF

Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AV-set_11e5xofA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_11ECOD (1.6)
BV-set_11e5xofB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_11ECOD (1.6)
CV-set_11e5xofC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_11ECOD (1.6)
DV-set_11e5xofD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_11ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
B2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
D2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A, B, C, D
PILRA, Paired immunoglobulin-like type 2 receptor alpha 1V-LIKE Homo sapiens (human) PILRA*01 V-LIKE-DOMAIN V-LIKE RPI 1V-LIKE IMGT (202415-0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Paired immunoglobulin-like type 2 receptor alpha
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		Peptide from Nitric oxide synthase, endothelial

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR013783Immunoglobulin-like foldHomologous Superfamily
A, B, C, D
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
A, B, C, D
IPR003599Immunoglobulin subtypeDomain
A, B, C, D
IPR013106Immunoglobulin V-set domainDomain
A, B, C, D
IPR007110Immunoglobulin-like domainDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR001709Flavoprotein pyridine nucleotide cytochrome reductaseDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR001433Oxidoreductase FAD/NAD(P)-bindingDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR001094Flavodoxin-likeDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR004030Nitric oxide synthase, N-terminalDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR023173NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamilyHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR008254Flavodoxin/nitric oxide synthaseDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR039261Ferredoxin-NADP reductase (FNR), nucleotide-binding domainHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR017927FAD-binding domain, ferredoxin reductase-typeDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR036119Nitric oxide synthase, N-terminal domain superfamilyHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR044944Nitric oxide synthase, domain 3 superfamilyHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR044943Nitric oxide synthase, domain 1 superfamilyHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR003097Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-bindingDomain
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR017938Riboflavin synthase-like beta-barrelHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR044940Nitric oxide synthase, domain 2 superfamilyHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR029039Flavoprotein-like superfamilyHomologous Superfamily
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		IPR012144Nitric-oxide synthase, eukaryoteFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B, C, D
Pharos:  Q9UKJ1
E [auth O],
F [auth P],
G [auth Q],
H [auth R]		Pharos:  P29474