5XCC

X-ray structure of Clostridium perfringens pili protein CppA

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AF_UNCLASSIFIEDe5xccA3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Prealbumin-likeF: F_UNCLASSIFIEDECOD (1.6)
APF17802e5xccA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Prealbumin-likeF: PF17802ECOD (1.6)
APF16569e5xccA2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Common fold of diphtheria toxin/transcription factors/cytochrome fF: PF16569ECOD (1.6)
BF_UNCLASSIFIEDe5xccB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Prealbumin-likeF: F_UNCLASSIFIEDECOD (1.6)
BPF17802e5xccB3 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Prealbumin-likeF: PF17802ECOD (1.6)
BPF16569e5xccB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Common fold of diphtheria toxin/transcription factors/cytochrome fF: PF16569ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF17802Prealbumin-like fold domain (SpaA)Prealbumin-like fold domainThis entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae [1]. Some members of this family contain an isopeptide bond.Domain
A, B
PF16569Gram-positive pilin backbone subunit 2, Cna-B-like domain (GramPos_pilinBB)Gram-positive pilin backbone subunit 2, Cna-B-like domainGramPos_pilinBB is one of the major backbone units of Gram-positive pili, such as those from S.pneumoniae [1]. There are three major pilin subunits that form the polymeric backbone of the pilin from S. pneumoniae, constructed of three transthyretin ...GramPos_pilinBB is one of the major backbone units of Gram-positive pili, such as those from S.pneumoniae [1]. There are three major pilin subunits that form the polymeric backbone of the pilin from S. pneumoniae, constructed of three transthyretin-like, CnaB, domains along with a crucial N-terminal domain, D1. The three Cna-B like domains are stabilised by internal Lys-Asn isopeptdie bonds, Gram-positive pili are formed from a single chain of covalently linked subunit proteins (pilins), usually comprising an adhesin at the distal tip, a major pilin that forms the polymer shaft and a minor pilin that mediates cell wall anchoring at the base [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Probable surface protein- -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B
IPR013783Immunoglobulin-like foldHomologous Superfamily
A, B
IPR032334Gram-positive pilin backbone subunit 2, Cna-B-like domainDomain
A, B
IPR041033Prealbumin-like fold domainDomain
A, B
IPR026466Fimbrial isopeptide formation D2 domainDomain
A, B
IPR048052Fimbrial subunit type 1-likeFamily