5WYJ

Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
T [auth BC]SCOP2B SuperfamilyUTPB complex component-like8061270 3002330 SCOP2B (2022-06-29)
B [auth 3B]SCOP2 FamilyFibrillarin homologue8063661 4000661 SCOP2 (2022-06-29)
B [auth 3B]SCOP2 SuperfamilyS-adenosyl-L-methionine-dependent methyltransferases8063662 3000118 SCOP2 (2022-06-29)
C [auth 3C]SCOP2B SuperfamilyS-adenosyl-L-methionine-dependent methyltransferases8063662 3000118 SCOP2B (2022-06-29)
W [auth CA]SCOP2B SuperfamilyRRP7 C-terminal domain-like8053722 3002219 SCOP2B (2022-06-29)
W [auth CA]SCOP2B SuperfamilyRNA-binding domain RBD8053724 3000110 SCOP2B (2022-06-29)
X [auth CB]SCOP2B SuperfamilyNucleotidyltransferase-like8053726 3000129 SCOP2B (2022-06-29)
X [auth CB]SCOP2B SuperfamilyPAP/OAS1 substrate-binding domain-like8053728 3000941 SCOP2B (2022-06-29)
X [auth CB]SCOP2B SuperfamilyPAP/Archaeal CCA-adding enzyme C-terminal domain-like8053729 3001147 SCOP2B (2022-06-29)
X [auth CB]SCOP2B SuperfamilyPAP/OAS1 substrate-binding domain-like8053727 3000941 SCOP2B (2022-06-29)
X [auth CB]SCOP2B SuperfamilyNucleotidyltransferase-like8053725 3000129 SCOP2B (2022-06-29)
X [auth CB]SCOP2B SuperfamilyPAP/Archaeal CCA-adding enzyme C-terminal domain-like8053730 3001147 SCOP2B (2022-06-29)
Y [auth E1]SCOP2B Superfamilyalpha/beta knot8037153 3001122 SCOP2B (2022-06-29)
Z [auth E2]SCOP2B Superfamilyalpha/beta knot8037153 3001122 SCOP2B (2022-06-29)
LA [auth SC]SCOP2B SuperfamilyRibosomal S3Ae-like8053211 3002166 SCOP2B (2022-06-29)
MA [auth SF]SCOP2B SuperfamilyNucleic acid-binding proteins8052759 3000135 SCOP2B (2022-06-29)
MA [auth SF]SCOP2B SuperfamilyAlpha-L RNA-binding motif8052758 3001473 SCOP2B (2022-06-29)
MA [auth SF]SCOP2B SuperfamilyTranslation proteins SH3-like KOW motif containing domain8052760 3000334 SCOP2B (2022-06-29)
NA [auth SG]SCOP2B SuperfamilyRibosomal protein S78065993 3000799 SCOP2B (2022-06-29)
OA [auth SH]SCOP2B SuperfamilyGS N-terminal domain-like8053173 3000408 SCOP2B (2022-06-29)
SA [auth SM]SCOP2B SuperfamilyNucleic acid-binding proteins8052738 3000135 SCOP2B (2022-06-29)
SA [auth SM]SCOP2B SuperfamilyRibosomal S17 N-terminal domain-like8052736 3002138 SCOP2B (2022-06-29)
TA [auth SN]SCOP2B SuperfamilyL30e-like8096946 3001739 SCOP2B (2022-06-29)
UA [auth SO]SCOP2B SuperfamilyS15/NS1 RNA-binding domain8052974 3001284 SCOP2B (2022-06-29)
UA [auth SO]SCOP2B SuperfamilyHomeodomain-like8052973 3000001 SCOP2B (2022-06-29)
VA [auth SP]SCOP2B SuperfamilyTranslational machinery components8095805 3000571 SCOP2B (2022-06-29)
WA [auth SR]SCOP2B SuperfamilyRibosomal protein S5 domain 2-like8103366 3000100 SCOP2B (2022-06-29)
XA [auth SX]SCOP2B SuperfamilyRibosomal protein S88096922 3000709 SCOP2B (2022-06-29)
BB [auth Sd]SCOP2B SuperfamilyNucleic acid-binding proteins8063430 3000135 SCOP2B (2022-06-29)
G [auth 3G]SCOP2B SuperfamilyL30e-like8033484 3001739 SCOP2B (2022-06-29)
H [auth 3H]SCOP2B SuperfamilyL30e-like8033484 3001739 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
Q [auth B1]PF04950e5wyjB12 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: PF04950ECOD (1.6)
Q [auth B1]PF08142e5wyjB14 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: PF08142ECOD (1.6)
Q [auth B1]PF04950e5wyjB13 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Aminomethyltransferase beta-barrel domainF: PF04950ECOD (1.6)
Q [auth B1]PF00009e5wyjB11 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00009ECOD (1.6)
R [auth BA]PF00400e5wyjBA2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
R [auth BA]PF04003e5wyjBA3 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: PF04003ECOD (1.6)
S [auth BB]PF00400e5wyjBB3 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
S [auth BB]PF04003e5wyjBB2 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: PF04003ECOD (1.6)
U [auth BD]PF00400e5wyjBD1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
B [auth 3B]PF01269e5wyj3B1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: PF01269ECOD (1.6)
C [auth 3C]PF01269e5wyj3C1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: PF01269ECOD (1.6)
V [auth BE]PF00400e5wyjBE2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
V [auth BE]PF12894e5wyjBE1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF12894ECOD (1.6)
V [auth BE]PF04192e5wyjBE3 A: alpha superhelicesX: Repetitive alpha hairpinsH: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 (From Topology)T: C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13F: PF04192ECOD (1.6)
W [auth CA]PF17799e5wyjCA1 A: a+b two layersX: Alpha-beta plaitsH: RNA-binding domain, RBD (From Topology)T: RNA-binding domain, RBDF: PF17799ECOD (1.6)
X [auth CB]PF17403e5wyjCB5 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: PAP/OAS1 substrate-binding domainF: PF17403ECOD (1.6)
X [auth CB]PF17406e5wyjCB4 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: PAP/OAS1 substrate-binding domainF: PF17406ECOD (1.6)
X [auth CB]PF17404e5wyjCB2 A: a+b two layersX: Alpha-beta plaitsH: PAP/Archaeal CCA-adding enzyme, C-terminal domain (From Topology)T: PAP/Archaeal CCA-adding enzyme, C-terminal domainF: PF17404ECOD (1.6)
X [auth CB]PF17407e5wyjCB3 A: a+b two layersX: Alpha-beta plaitsH: PAP/Archaeal CCA-adding enzyme, C-terminal domain (From Topology)T: PAP/Archaeal CCA-adding enzyme, C-terminal domainF: PF17407ECOD (1.6)
X [auth CB]PF03813e5wyjCB6 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: PF03813ECOD (1.6)
X [auth CB]PF17405e5wyjCB1 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: PF17405ECOD (1.6)
Y [auth E1]PF03587e5wyjE11 A: a/b three-layered sandwichesX: alpha/beta knot (From Topology)H: alpha/beta knot (From Topology)T: alpha/beta knotF: PF03587ECOD (1.6)
Z [auth E2]PF03587e5wyjE21 A: a/b three-layered sandwichesX: alpha/beta knot (From Topology)H: alpha/beta knot (From Topology)T: alpha/beta knotF: PF03587ECOD (1.6)
AA [auth E3]PF05291e5wyjE31 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF05291ECOD (1.6)
CA [auth K1]PF17903e5wyjK11 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Eukaryotic type KH-domain (KH-domain type I)F: PF17903ECOD (1.6)
CA [auth K1]PF21800e5wyjK12 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Eukaryotic type KH-domain (KH-domain type I)F: PF21800ECOD (1.6)
DA [auth MA]PF00163,PF01479e5wyjMA1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: PF00163,PF01479ECOD (1.6)
EA [auth MB]PF04427e5wyjMB1 A: a/b three-layered sandwichesX: Anticodon-binding domain of Class II aaRS (From Topology)H: Anticodon-binding domain of Class II aaRS (From Topology)T: Anticodon-binding domain of Class II aaRSF: PF04427ECOD (1.6)
D [auth 3D]PF01798e5wyj3D1 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: Nop C-terminal domainF: PF01798ECOD (1.6)
D [auth 3D]PF01798e5wyj3D2 A: alpha complex topologyX: Nop N-terminal domain (From Topology)H: Nop N-terminal domain (From Topology)T: Nop N-terminal domainF: PF01798ECOD (1.6)
D [auth 3D]PF08156e5wyj3D3 A: mixed a+b and a/bX: Nop N-terminal domain (From Topology)H: Nop N-terminal domain (From Topology)T: Nop N-terminal domainF: PF08156ECOD (1.6)
GA [auth P1]PF17903e5wyjP11 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Eukaryotic type KH-domain (KH-domain type I)F: PF17903ECOD (1.6)
GA [auth P1]PF22891e5wyjP12 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Eukaryotic type KH-domain (KH-domain type I)F: PF22891ECOD (1.6)
HA [auth R1]PF01137e5wyjR12 A: a+b two layersX: IF3-likeH: EPT/RTPC-like (From Topology)T: EPT/RTPC-likeF: PF01137ECOD (1.6)
HA [auth R1]PF05189e5wyjR11 A: a+b three layersX: Thioredoxin-likeH: RNA 3'-terminal phosphate cyclase, RPTC, insert domain (From Topology)T: RNA 3'-terminal phosphate cyclase, RPTC, insert domainF: PF05189ECOD (1.6)
IA [auth R2]F_UNCLASSIFIEDe5wyjR21 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: F_UNCLASSIFIEDECOD (1.6)
LA [auth SC]PF01015e5wyjSC1 A: beta barrelsX: Ribosomal protein L25-likeH: 40S ribosomal protein S3A N-terminal domain (From Topology)T: 40S ribosomal protein S3A N-terminal domainF: PF01015ECOD (1.6)
LA [auth SC]PF01015e5wyjSC2 A: a+b two layersX: T-foldH: 40S ribosomal protein S3A C-terminal domain (From Topology)T: 40S ribosomal protein S3A C-terminal domainF: PF01015ECOD (1.6)
MA [auth SF]PF00900e5wyjSF1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF00900ECOD (1.6)
MA [auth SF]PF00467,PF16121e5wyjSF3 A: beta barrelsX: SH3H: SH3T: SH3F: PF00467,PF16121ECOD (1.6)
MA [auth SF]PF00900,PF01479,PF08071e5wyjSF2 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: PF00900,PF01479,PF08071ECOD (1.6)
NA [auth SG]PF00177e5wyjSG1 A: alpha arraysX: Ribosomal protein S7 (From Topology)H: Ribosomal protein S7 (From Topology)T: Ribosomal protein S7F: PF00177ECOD (1.6)
OA [auth SH]PF01092e5wyjSH1 A: beta barrelsX: Ribosomal protein L25-likeH: Ribosomal protein L25-like (From Topology)T: Ribosomal protein L25-likeF: PF01092ECOD (1.6)
PA [auth SI]PF01251e5wyjSI1 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: 40S ribosomal protein S7-A (From Topology)T: 40S ribosomal protein S7-AF: PF01251ECOD (1.6)
E [auth 3E]PF01798e5wyj3E2 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: Nop C-terminal domainF: PF01798ECOD (1.6)
E [auth 3E]PF01798e5wyj3E3 A: alpha complex topologyX: Nop N-terminal domain (From Topology)H: Nop N-terminal domain (From Topology)T: Nop N-terminal domainF: PF01798ECOD (1.6)
E [auth 3E]PF08156e5wyj3E1 A: mixed a+b and a/bX: Nop N-terminal domain (From Topology)H: Nop N-terminal domain (From Topology)T: Nop N-terminal domainF: PF08156ECOD (1.6)
QA [auth SJ]PF01201e5wyjSJ1 A: beta barrelsX: Ribosomal protein L14-likeH: Ribosomal protein L14-related (From Topology)T: Ribosomal protein L14-relatedF: PF01201ECOD (1.6)
RA [auth SK]PF00163,PF01479e5wyjSK1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: PF00163,PF01479ECOD (1.6)
SA [auth SM]PF00366,PF16205e5wyjSM1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF00366,PF16205ECOD (1.6)
TA [auth SN]PF01248e5wyjSN1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: PF01248ECOD (1.6)
UA [auth SO]PF08069e5wyjSO1 A: alpha arraysX: HTHH: 40S ribosomal protein S13 N-terminal domain (From Topology)T: 40S ribosomal protein S13 N-terminal domainF: PF08069ECOD (1.6)
UA [auth SO]PF00312e5wyjSO2 A: alpha arraysX: S15/NS1 RNA-binding domain (From Topology)H: S15/NS1 RNA-binding domain (From Topology)T: S15/NS1 RNA-binding domainF: PF00312ECOD (1.6)
VA [auth SP]PF00411e5wyjSP1 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: PF00411ECOD (1.6)
WA [auth SR]PF00380e5wyjSR1 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: PF00380ECOD (1.6)
XA [auth SX]PF00410e5wyjSX2 A: a+b two layersX: R3H domain-likeH: Ribosomal protein S8, N-terminal domain (From Topology)T: Ribosomal protein S8, N-terminal domainF: PF00410ECOD (1.6)
XA [auth SX]PF00410e5wyjSX1 A: a+b two layersX: Ribosomal protein S8, C-terminal domain (From Topology)H: Ribosomal protein S8, C-terminal domain (From Topology)T: Ribosomal protein S8, C-terminal domainF: PF00410ECOD (1.6)
YA [auth SY]PF00164e5wyjSY1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF00164ECOD (1.6)
ZA [auth SZ]PF01282e5wyjSZ1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal proteins S24e, L23 and L15e (From Topology)T: Ribosomal proteins S24e, L23 and L15eF: PF01282ECOD (1.6)
F [auth 3F]PF00400e5wyj3F1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
AB [auth Sc]PF01667e5wyjSc1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: PF01667ECOD (1.6)
BB [auth Sd]PF01200e5wyjSd1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF01200ECOD (1.6)
CB [auth Sf]PF04758e5wyjSf1 A: extended segmentsX: 40S ribosomal protein S30 (S30e) (From Topology)H: 40S ribosomal protein S30 (S30e) (From Topology)T: 40S ribosomal protein S30 (S30e)F: PF04758ECOD (1.6)
DB [auth Sg]PF01599e5wyjSg1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: PF01599ECOD (1.6)
HB [auth U4]PF04900e5wyjU41 A: a/b three-layered sandwichesX: HAD domain-likeH: HAD domain-relatedT: PIN domain-likeF: PF04900ECOD (1.6)
IB [auth U5]PF00687e5wyjU51 A: a+b two layersX: a+b domain in Ribosomal protein L1 (From Topology)H: a+b domain in Ribosomal protein L1 (From Topology)T: a+b domain in Ribosomal protein L1F: PF00687ECOD (1.6)
IB [auth U5]PF00687e5wyjU52 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Rossmann-like domain in Ribosomal protein L1 (From Topology)T: Rossmann-like domain in Ribosomal protein L1F: PF00687ECOD (1.6)
G [auth 3G]PF01248e5wyj3G1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: PF01248ECOD (1.6)
H [auth 3H]PF01248e5wyj3H1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: PF01248ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
N [auth AE]PF12397U3 small nucleolar RNA-associated protein 10 (U3snoRNP10)U3 small nucleolar RNA-associated protein 10- Family
Q [auth B1]PF00004ATPase family associated with various cellular activities (AAA) (AAA)ATPase family associated with various cellular activities (AAA)AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes [2].Domain
R [auth BA]PF04003Dip2/Utp12 Family (Utp12)Dip2/Utp12 Family- Family
R [auth BA]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
S [auth BB]PF04003Dip2/Utp12 Family (Utp12)Dip2/Utp12 Family- Family
S [auth BB]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
T [auth BC]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
T [auth BC]PF08625Utp13 specific WD40 associated domain (Utp13)Utp13 specific WD40 associated domainUtp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome [1]. Pwp2 is capable o ...Utp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome [1]. Pwp2 is capable of interacting directly with the 35 S pre-rRNA 5' end [1].
Domain
U [auth BD]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
B [auth 3B],
C [auth 3C]
PF01269Fibrillarin (Fibrillarin)Fibrillarin- Domain
V [auth BE]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
W [auth CA]PF17799Rrp7 RRM-like N-terminal domain (RRM_Rrp7)Rrp7 RRM-like N-terminal domainThis domain corresponds to the N-terminal RNA-binding domain found in the Rrp7 protein. It has an RRM-like fold with a circular permutation [1].Domain
W [auth CA]PF12923Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain (RRP7)Ribosomal RNA-processing protein 7 (RRP7) C-terminal domainRRP7 is an essential protein in yeast that is involved in pre-rRNA processing and ribosome assembly [1]. It is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle [1-2].Domain
X [auth CB]PF03813Nrap protein domain 1 (Nrap)Nrap protein domain 1Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1]. This domain has a nucleotidyltransferase structure.
Domain
X [auth CB]PF17403Nrap protein PAP/OAS-like domain (Nrap_D2)Nrap protein PAP/OAS-like domainMembers of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
X [auth CB]PF17406Nrap protein PAP/OAS1-like domain 5 (Nrap_D5)Nrap protein PAP/OAS1-like domain 5Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
X [auth CB]PF17407Nrap protein domain 6 (Nrap_D6)Nrap protein domain 6Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
X [auth CB]PF17404Nrap protein domain 3 (Nrap_D3)Nrap protein domain 3Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
X [auth CB]PF17405Nrap protein nucleotidyltransferase domain 4 (Nrap_D4)Nrap protein nucleotidyltransferase domain 4Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a ...Members of this family are nucleolar RNA-associated proteins (Nrap) which are highly conserved from yeast (Saccharomyces cerevisiae) to human. In the mouse, Nrap is ubiquitously expressed and is specifically localised in the nucleolus [1]. Nrap is a large nucleolar protein (of more than 1000 amino acids). Nrap appears to be associated with ribosome biogenesis by interacting with pre-rRNA primary transcript [1].
Domain
Y [auth E1],
Z [auth E2]
PF03587EMG1/NEP1 methyltransferase (EMG1)EMG1/NEP1 methyltransferase- Family
AA [auth E3]PF05291Bystin (Bystin)Bystin- Family
CA [auth K1]PF17903Krr1 KH1 domain (KH_8)Krr1 KH1 domainThis entry represents the first KH domain in the KRR1 protein [1]. Krr1 is a ribosomal assembly factor. The KH1 domain is a divergent KH domain that lacks the RNA-binding GXXG motif and is involved in binding another assembly factor, Kri1 [1].Domain
CA [auth K1]PF21800KRR1 small subunit processome component, second KH domain (KRR1-like_KH2)KRR1 small subunit processome component, second KH domainThis is the second K homology domain (KH2) found in KRR1 small subunit processome component from the fungus Chaetomium thermophilum and similar eukaryotic sequences.Domain
DA [auth MA]PF00163Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4)Ribosomal protein S4/S9 N-terminal domain- Family
DA [auth MA]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
EA [auth MB]PF04427Brix domain (Brix)Brix domain- Domain
FA [auth MC]PF04006Mpp10 protein (Mpp10)Mpp10 protein- Family
D [auth 3D]PF08156NOP5NT (NUC127) domain (NOP5NT)NOP5NT (NUC127) domainThis N terminal domain is found in RNA-binding proteins of the NOP5 family [1].Domain
D [auth 3D]PF01798snoRNA binding domain, fibrillarin (Nop)snoRNA binding domain, fibrillarin- Family
GA [auth P1]PF17903Krr1 KH1 domain (KH_8)Krr1 KH1 domainThis entry represents the first KH domain in the KRR1 protein [1]. Krr1 is a ribosomal assembly factor. The KH1 domain is a divergent KH domain that lacks the RNA-binding GXXG motif and is involved in binding another assembly factor, Kri1 [1].Domain
HA [auth R1]PF05189RNA 3'-terminal phosphate cyclase (RTC), insert domain (RTC_insert)RNA 3'-terminal phosphate cyclase (RTC), insert domainRNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation o ...RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation of the covalent AMP-cyclase intermediate [1]. The structure of RTC demonstrates that RTCs are comprised two domain. The larger domain contains an insert domain of approximately 100 amino acids [1].
Domain
HA [auth R1]PF01137RNA 3'-terminal phosphate cyclase (RTC)RNA 3'-terminal phosphate cyclaseRNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation o ...RNA cyclases are a family of RNA-modifying enzymes that are conserved in all cellular organisms. They catalyse the ATP-dependent conversion of the 3'-phosphate to the 2',3'-cyclic phosphodiester at the end of RNA, in a reaction involving formation of the covalent AMP-cyclase intermediate [1]. The structure of RTC demonstrates that RTCs are comprised two domain. The larger domain contains an insert domain of approximately 100 amino acids [1].
Domain
LA [auth SC]PF01015Ribosomal S3Ae family (Ribosomal_S3Ae)Ribosomal S3Ae family- Family
MA [auth SF]PF00900Ribosomal family S4e (Ribosomal_S4e)Ribosomal family S4e- Family
MA [auth SF]PF1612140S ribosomal protein S4 C-terminus (40S_S4_C)40S ribosomal protein S4 C-terminus- Family
MA [auth SF]PF08071RS4NT (NUC023) domain (RS4NT)RS4NT (NUC023) domainThis is the N-terminal domain of Ribosomal S4 / S4e proteins. This domain is associated with S4 and KOW domains [1].Domain
MA [auth SF]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
MA [auth SF]PF00467KOW motif (KOW)KOW motif- Family
NA [auth SG]PF00177Ribosomal protein S7p/S5e (Ribosomal_S7)Ribosomal protein S7p/S5eThis family contains ribosomal protein S7 from prokaryotes and S5 from eukaryotes.Domain
OA [auth SH]PF01092Ribosomal protein S6e (Ribosomal_S6e)Ribosomal protein S6e- Family
PA [auth SI]PF01251Ribosomal protein S7e (Ribosomal_S7e)Ribosomal protein S7e- Family
E [auth 3E]PF08156NOP5NT (NUC127) domain (NOP5NT)NOP5NT (NUC127) domainThis N terminal domain is found in RNA-binding proteins of the NOP5 family [1].Domain
E [auth 3E]PF01798snoRNA binding domain, fibrillarin (Nop)snoRNA binding domain, fibrillarin- Family
QA [auth SJ]PF01201Ribosomal protein S8e (Ribosomal_S8e)Ribosomal protein S8e- Family
RA [auth SK]PF00163Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4)Ribosomal protein S4/S9 N-terminal domain- Family
RA [auth SK]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
SA [auth SM]PF00366Ribosomal protein S17 (Ribosomal_S17)Ribosomal protein S17- Domain
SA [auth SM]PF16205Ribosomal_S17 N-terminal (Ribosomal_S17_N)Ribosomal_S17 N-terminal- Family
TA [auth SN]PF01248Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)Ribosomal protein L7Ae/L30e/S12e/Gadd45 familyThis family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].
Domain
UA [auth SO]PF08069Ribosomal S13/S15 N-terminal domain (Ribosomal_S13_N)Ribosomal S13/S15 N-terminal domainThis domain is found at the N-terminus of ribosomal S13 and S15 proteins. This domain is also identified as NUC021 [1].Domain
UA [auth SO]PF00312Ribosomal protein S15 (Ribosomal_S15)Ribosomal protein S15- Domain
VA [auth SP]PF00411Ribosomal protein S11 (Ribosomal_S11)Ribosomal protein S11- Family
WA [auth SR]PF00380Ribosomal protein S9/S16 (Ribosomal_S9)Ribosomal protein S9/S16- Family
XA [auth SX]PF00410Ribosomal protein S8 (Ribosomal_S8)Ribosomal protein S8- Domain
YA [auth SY]PF00164Ribosomal protein S12/S23 (Ribosom_S12_S23)Ribosomal protein S12/S23- Family
ZA [auth SZ]PF01282Ribosomal protein S24e (Ribosomal_S24e)Ribosomal protein S24e- Family
AB [auth Sc]PF01667Ribosomal protein S27 (Ribosomal_S27e)Ribosomal protein S27- Family
BB [auth Sd]PF01200Ribosomal protein S28e (Ribosomal_S28e)Ribosomal protein S28e- Family
CB [auth Sf]PF04758Ribosomal protein S30 (Ribosomal_S30)Ribosomal protein S30- Family
DB [auth Sg]PF01599Ribosomal protein S27a (Ribosomal_S27)Ribosomal protein S27aThis family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins ...This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis [3]. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins [2].
Domain
HB [auth U4]PF04900Fcf1 (Fcf1)Fcf1- Family
IB [auth U5]PF00687Ribosomal protein L1p/L10e family (Ribosomal_L1)Ribosomal protein L1p/L10e familyThis family includes prokaryotic L1 and eukaryotic L10.Domain
G [auth 3G],
H [auth 3H]
PF01248Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)Ribosomal protein L7Ae/L30e/S12e/Gadd45 familyThis family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth 3A]U3 RNA---
L [auth AC]Utp8---
M [auth AD]Utp9---
N [auth AE]U3 small nucleolar RNA-associated protein 10,Utp10
O [auth AF]Utp15---
P [auth AG]Utp17---
Q [auth B1]Ribosome biogenesis protein BMS1
R [auth BA]Periodic tryptophan protein 2
S [auth BB]U3 small nucleolar RNA-associated protein 12
T [auth BC]U3 small nucleolar RNA-associated protein 13
U [auth BD]U3 small nucleolar RNA-associated protein 18-
B [auth 3B],
C [auth 3C]
rRNA 2'-O-methyltransferase fibrillarin
V [auth BE]U3 small nucleolar RNA-associated protein 21-
W [auth CA]Ribosomal RNA-processing protein 7
X [auth CB]U3 small nucleolar RNA-associated protein 22
Y [auth E1],
Z [auth E2]
Ribosomal RNA small subunit methyltransferase NEP1
AA [auth E3]Essential nuclear protein 1
BA [auth E4]Enp2---
CA [auth K1]KRR1 small subunit processome component
DA [auth MA]U3 small nucleolar ribonucleoprotein protein IMP3
EA [auth MB]U3 small nucleolar ribonucleoprotein protein IMP4
FA [auth MC]Mpp10,U3 small nucleolar RNA-associated protein MPP10
D [auth 3D]Nucleolar protein 56
GA [auth P1]Pre-rRNA-processing protein PNO1
HA [auth R1]RNA 3'-terminal phosphate cyclase-like protein
IA [auth R2]rRNA biogenesis protein RRP5
JA [auth S1]Sof1---
KA [auth SA]18S ribosomal RNA---
LA [auth SC]40S ribosomal protein S1-A
MA [auth SF]40S ribosomal protein S4-A
NA [auth SG]40S ribosomal protein S5
OA [auth SH]40S ribosomal protein S6-A
PA [auth SI]40S ribosomal protein S7-A
E [auth 3E]Nucleolar protein 58
QA [auth SJ]40S ribosomal protein S8-A
RA [auth SK]40S ribosomal protein S9-A
SA [auth SM]40S ribosomal protein S11-A
TA [auth SN]40S ribosomal protein S12
UA [auth SO]40S ribosomal protein S13
VA [auth SP]40S ribosomal protein S14-A
WA [auth SR]40S ribosomal protein S16-A
XA [auth SX]40S ribosomal protein S22-A
YA [auth SY]40S ribosomal protein S23-A
ZA [auth SZ]40S ribosomal protein S24-A
F [auth 3F]Ribosomal RNA-processing protein 9
AB [auth Sc]40S ribosomal protein S27-A
BB [auth Sd]40S ribosomal protein S28-A
CB [auth Sf]40S ribosomal protein S30-A
DB [auth Sg]Ubiquitin-40S ribosomal protein S31
EB [auth U1]Utp7---
FB [auth U2]Utp11---
GB [auth U3]Utp20---
HB [auth U4]rRNA-processing protein FCF1
IB [auth U5]Ribosome biogenesis protein UTP30
JB [auth UA]Helical domain protein---
G [auth 3G],
H [auth 3H]
13 kDa ribonucleoprotein-associated protein
KB [auth UB]Helical domain protein---
LB [auth UC]Unassigned helices---
I [auth 5A]5ETS RNA---
J [auth AA]Utp4---
K [auth AB]Utp5---

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
N [auth AE]IPR016024Armadillo-type foldHomologous Superfamily
N [auth AE]IPR040191U3 small nucleolar RNA-associated protein 10Family
N [auth AE]IPR021133HEAT, type 2Repeat
N [auth AE]IPR011989Armadillo-like helicalHomologous Superfamily
N [auth AE]IPR022125U3 small nucleolar RNA-associated protein 10, N-terminalDomain
N [auth AE]IPR012954BP28, C-terminal domainDomain
Q [auth B1]IPR007034Ribosome biogenesis protein BMS1/TSR1, C-terminalDomain
Q [auth B1]IPR039761Ribosome biogenesis protein Bms1/Tsr1Family
Q [auth B1]IPR003959ATPase, AAA-type, coreDomain
Q [auth B1]IPR012948AARP2CNDomain
Q [auth B1]IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
Q [auth B1]IPR030387Bms1/Tsr1-type G domainDomain
Q [auth B1]IPR037875Ribosome biogenesis protein Bms1, N-terminalDomain
R [auth BA]IPR024977Anaphase-promoting complex subunit 4-like, WD40 domainDomain
R [auth BA]IPR019775WD40 repeat, conserved siteConserved Site
R [auth BA]IPR007148Small-subunit processome, Utp12Domain
R [auth BA]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
R [auth BA]IPR011047Quinoprotein alcohol dehydrogenase-like superfamilyHomologous Superfamily
R [auth BA]IPR001680WD40 repeatRepeat
R [auth BA]IPR020472G-protein beta WD-40 repeatRepeat
R [auth BA]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
R [auth BA]IPR027145Periodic tryptophan protein 2Family
S [auth BB]IPR019775WD40 repeat, conserved siteConserved Site
S [auth BB]IPR007148Small-subunit processome, Utp12Domain
S [auth BB]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
S [auth BB]IPR001680WD40 repeatRepeat
S [auth BB]IPR020472G-protein beta WD-40 repeatRepeat
S [auth BB]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
T [auth BC]IPR019775WD40 repeat, conserved siteConserved Site
T [auth BC]IPR013934U3 small nucleolar RNA-associated protein 13, C-terminalDomain
T [auth BC]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
T [auth BC]IPR001680WD40 repeatRepeat
T [auth BC]IPR020472G-protein beta WD-40 repeatRepeat
T [auth BC]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
U [auth BD]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
U [auth BD]IPR001680WD40 repeatRepeat
U [auth BD]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
U [auth BD]IPR045161U3 small nucleolar RNA-associated protein 18Family
B [auth 3B],
C [auth 3C]
IPR000692rRNA 2'-O-methyltransferase fibrillarin-likeFamily
B [auth 3B],
C [auth 3C]
IPR029063S-adenosyl-L-methionine-dependent methyltransferase superfamilyHomologous Superfamily
B [auth 3B],
C [auth 3C]
IPR020813Fibrillarin, conserved siteConserved Site
V [auth BE]IPR007319Small-subunit processome, Utp21Domain
V [auth BE]IPR024977Anaphase-promoting complex subunit 4-like, WD40 domainDomain
V [auth BE]IPR019775WD40 repeat, conserved siteConserved Site
V [auth BE]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
V [auth BE]IPR011047Quinoprotein alcohol dehydrogenase-like superfamilyHomologous Superfamily
V [auth BE]IPR001680WD40 repeatRepeat
V [auth BE]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
W [auth CA]IPR040446Ribosomal RNA-processing protein 7Family
W [auth CA]IPR040447Rrp7, RRM-like N-terminal domainDomain
W [auth CA]IPR024326Ribosomal RNA-processing protein 7, C-terminal domainDomain
X [auth CB]IPR035367Nrap protein, domain 2Domain
X [auth CB]IPR035368Nrap protein, domain 3Domain
X [auth CB]IPR035370Nrap protein, domain 5Domain
X [auth CB]IPR005554NOL6/Upt22Family
X [auth CB]IPR035369Nrap protein, domain 4Domain
X [auth CB]IPR035082Nrap protein domain 1Domain
X [auth CB]IPR035371Nrap protein, domain 6Domain
Y [auth E1],
Z [auth E2]
IPR029026tRNA (guanine-N1-)-methyltransferase, N-terminalHomologous Superfamily
Y [auth E1],
Z [auth E2]
IPR005304Ribosomal biogenesis, methyltransferase, EMG1/NEP1Family
Y [auth E1],
Z [auth E2]
IPR029028Alpha/beta knot methyltransferasesHomologous Superfamily
AA [auth E3]IPR007955BystinFamily
CA [auth K1]IPR041174KRR1 small subunit processome component, first KH domainDomain
CA [auth K1]IPR024166Ribosomal RNA assembly KRR1Family
CA [auth K1]IPR004087K Homology domainDomain
CA [auth K1]IPR048550KRR1 small subunit processome component, first KH domain, eukaryotesDomain
CA [auth K1]IPR036612K Homology domain, type 1 superfamilyHomologous Superfamily
CA [auth K1]IPR048548KRR1 small subunit processome component, second KH domainDomain
CA [auth K1]IPR048549KRR1 small subunit processome component, second KH domain, eukaryotesDomain
DA [auth MA]IPR002942RNA-binding S4 domainDomain
DA [auth MA]IPR022801Small ribosomal subunit protein uS4Family
DA [auth MA]IPR001912Small ribosomal subunit protein uS4, N-terminalDomain
DA [auth MA]IPR036986RNA-binding S4 domain superfamilyHomologous Superfamily
EA [auth MB]IPR044281U3 snoRNP protein/Ribosome production factor 1Family
EA [auth MB]IPR007109Brix domainDomain
FA [auth MC]IPR012173U3 small nucleolar ribonucleoprotein complex, subunit Mpp10Family
D [auth 3D]IPR042239Nop, C-terminal domainHomologous Superfamily
D [auth 3D]IPR012974Nucleolar protein 58/56, N-terminalDomain
D [auth 3D]IPR002687Nop domainDomain
D [auth 3D]IPR012976NOSICDomain
D [auth 3D]IPR036070Nop domain superfamilyHomologous Superfamily
D [auth 3D]IPR045056Nucleolar protein Nop56/Nop58Family
GA [auth P1]IPR041174KRR1 small subunit processome component, first KH domainDomain
GA [auth P1]IPR036612K Homology domain, type 1 superfamilyHomologous Superfamily
HA [auth R1]IPR013792RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/betaHomologous Superfamily
HA [auth R1]IPR023797RNA 3'-terminal phosphate cyclase domainDomain
HA [auth R1]IPR000228RNA 3'-terminal phosphate cyclaseFamily
HA [auth R1]IPR020719RNA 3'-terminal phosphate cyclase-like, conserved siteConserved Site
HA [auth R1]IPR037136RNA 3'-terminal phosphate cyclase domain superfamilyHomologous Superfamily
HA [auth R1]IPR016443RNA 3'-terminal phosphate cyclase type 2Family
HA [auth R1]IPR013791RNA 3'-terminal phosphate cyclase, insert domainDomain
HA [auth R1]IPR036553RNA 3'-terminal phosphate cyclase, insert domain superfamilyHomologous Superfamily
IA [auth R2]IPR048059rRNA biogenesis protein RRP5, S1 domain, first repeatDomain
IA [auth R2]IPR011990Tetratricopeptide-like helical domain superfamilyHomologous Superfamily
IA [auth R2]IPR003029S1 domainDomain
IA [auth R2]IPR048058rRNA biogenesis protein RRP5, S1 domain, eleventh repeatDomain
IA [auth R2]IPR003107HAT (Half-A-TPR) repeatRepeat
IA [auth R2]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
IA [auth R2]IPR045209rRNA biogenesis protein Rrp5Family
LA [auth SC]IPR001593Small ribosomal subunit protein eS1Family
LA [auth SC]IPR018281Small ribosomal subunit protein eS1, conserved siteConserved Site
LA [auth SC]IPR027500Small ribosomal subunit protein eS1, eukaryotesFamily
MA [auth SF]IPR018199Small ribosomal subunit protein eS4, N-terminal, conserved siteConserved Site
MA [auth SF]IPR013843Small ribosomal subunit protein eS4, N-terminalDomain
MA [auth SF]IPR032277Small ribosomal subunit protein eS4, C-terminal domainDomain
MA [auth SF]IPR002942RNA-binding S4 domainDomain
MA [auth SF]IPR013845Small ribosomal subunit protein eS4, central regionDomain
MA [auth SF]IPR000876Small ribosomal subunit protein eS4Family
MA [auth SF]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
MA [auth SF]IPR038237Small ribosomal subunit protein eS4, central domain superfamilyHomologous Superfamily
MA [auth SF]IPR041982Small ribosomal subunit protein eS4, KOW domainDomain
MA [auth SF]IPR036986RNA-binding S4 domain superfamilyHomologous Superfamily
MA [auth SF]IPR005824KOWDomain
NA [auth SG]IPR020606Small ribosomal subunit protein uS7, conserved siteConserved Site
NA [auth SG]IPR036823Small ribosomal subunit protein uS7 domain superfamilyHomologous Superfamily
NA [auth SG]IPR000235Small ribosomal subunit protein uS7Family
NA [auth SG]IPR023798Small ribosomal subunit protein uS7 domainDomain
NA [auth SG]IPR005716Ribosomal protein uS7, eukaryotic/archaealFamily
OA [auth SH]IPR014401Small ribosomal subunit protein eS6-likeFamily
OA [auth SH]IPR001377Small ribosomal subunit protein eS6Family
OA [auth SH]IPR018282Small ribosomal subunit protein eS6, conserved siteConserved Site
PA [auth SI]IPR000554Small ribosomal subunit protein eS7Family
PA [auth SI]IPR047861Small ribosomal subunit protein eS7, conserved siteConserved Site
E [auth 3E]IPR042239Nop, C-terminal domainHomologous Superfamily
E [auth 3E]IPR012974Nucleolar protein 58/56, N-terminalDomain
E [auth 3E]IPR002687Nop domainDomain
E [auth 3E]IPR012976NOSICDomain
E [auth 3E]IPR036070Nop domain superfamilyHomologous Superfamily
E [auth 3E]IPR045056Nucleolar protein Nop56/Nop58Family
QA [auth SJ]IPR001047Small ribosomal subunit protein eS8Family
QA [auth SJ]IPR042563Small ribosomal subunit protein eS8 subdomain, eukaryotesHomologous Superfamily
QA [auth SJ]IPR022309Ribosomal protein eS8/ribosomal biogenesis NSA2Family
QA [auth SJ]IPR018283Small ribosomal subunit protein eS8, conserved siteConserved Site
RA [auth SK]IPR002942RNA-binding S4 domainDomain
RA [auth SK]IPR022801Small ribosomal subunit protein uS4Family
RA [auth SK]IPR018079Small ribosomal subunit protein uS4, conserved siteConserved Site
RA [auth SK]IPR001912Small ribosomal subunit protein uS4, N-terminalDomain
RA [auth SK]IPR005710Small ribosomal subunit protein uS4, eukaryotic/archaealFamily
RA [auth SK]IPR036986RNA-binding S4 domain superfamilyHomologous Superfamily
SA [auth SM]IPR019979Small ribosomal subunit protein uS17, conserved siteConserved Site
SA [auth SM]IPR032440Small ribosomal subunit protein uS17, N-terminalDomain
SA [auth SM]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
SA [auth SM]IPR000266Small ribosomal subunit protein uS17Family
SA [auth SM]IPR028333Small ribosomal subunit protein uS17, archaeal/eukaryoticFamily
TA [auth SN]IPR000530Small ribosomal subunit protein eS12Family
TA [auth SN]IPR004038Ribosomal protein eL8/eL30/eS12/Gadd45Domain
TA [auth SN]IPR029064Ribosomal protein eL30-like superfamilyHomologous Superfamily
TA [auth SN]IPR047860Small ribosomal subunit protein eS12, conserved siteConserved Site
UA [auth SO]IPR012606Small ribosomal subunit protein uS15, N-terminalDomain
UA [auth SO]IPR009068uS15/NS1, RNA-binding domain superfamilyHomologous Superfamily
UA [auth SO]IPR000589Small ribosomal subunit protein uS15Family
UA [auth SO]IPR023029Small ribosomal subunit protein uS15, archaea/eukaryotesFamily
VA [auth SP]IPR001971Small ribosomal subunit protein uS11Family
VA [auth SP]IPR036967Small ribosomal subunit protein uS11 superfamilyHomologous Superfamily
VA [auth SP]IPR018102Small ribosomal subunit protein uS11, conserved siteConserved Site
WA [auth SR]IPR020574Small ribosomal subunit protein uS9, conserved siteConserved Site
WA [auth SR]IPR020568Ribosomal protein uS5 domain 2-type superfamilyHomologous Superfamily
WA [auth SR]IPR000754Small ribosomal subunit protein uS9Family
WA [auth SR]IPR014721Small ribosomal subunit protein uS5 domain 2-type fold, subgroupHomologous Superfamily
XA [auth SX]IPR000630Small ribosomal subunit protein uS8Family
XA [auth SX]IPR047863Small ribosomal subunit protein uS8, conserved siteConserved Site
XA [auth SX]IPR035987Small ribosomal subunit protein uS8 superfamilyHomologous Superfamily
YA [auth SY]IPR006032Small ribosomal subunit protein uS12Family
YA [auth SY]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
YA [auth SY]IPR005680Small ribosomal subunit protein uS12, eukaryotic/archaealFamily
ZA [auth SZ]IPR001976Small ribosomal subunit protein eS24Family
ZA [auth SZ]IPR012678Ribosomal protein uL23/eL15/eS24 core domain superfamilyHomologous Superfamily
ZA [auth SZ]IPR018098Small ribosomal subunit protein eS24 conserved siteConserved Site
F [auth 3F]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
F [auth 3F]IPR039241Ribosomal RNA-processing protein Rrp9-likeFamily
F [auth 3F]IPR001680WD40 repeatRepeat
F [auth 3F]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
AB [auth Sc]IPR023407Small ribosomal subunit protein eS27, zinc-binding domain superfamilyHomologous Superfamily
AB [auth Sc]IPR000592Small ribosomal subunit protein eS27Family
AB [auth Sc]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
BB [auth Sd]IPR028626Ribosomal protein eS28 conserved siteConserved Site
BB [auth Sd]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
BB [auth Sd]IPR000289Small ribosomal subunit protein eS28Family
CB [auth Sf]IPR006846Small ribosomal subunit protein eS30Family
DB [auth Sg]IPR019954Ubiquitin conserved siteConserved Site
DB [auth Sg]IPR000626Ubiquitin-like domainDomain
DB [auth Sg]IPR038582Small ribosomal subunit protein eS31 eukaryotic-type superfamilyHomologous Superfamily
DB [auth Sg]IPR002906Small ribosomal subunit protein eS31Domain
DB [auth Sg]IPR019956Ubiquitin domainDomain
DB [auth Sg]IPR029071Ubiquitin-like domain superfamilyHomologous Superfamily
DB [auth Sg]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
HB [auth U4]IPR002716PIN domainDomain
HB [auth U4]IPR029060PIN-like domain superfamilyHomologous Superfamily
HB [auth U4]IPR006984rRNA-processing protein Fcf1/Utp23Family
HB [auth U4]IPR037503rRNA-processing protein Fcf1, PIN domainDomain
IB [auth U5]IPR023674Ribosomal protein uL1-likeHomologous Superfamily
IB [auth U5]IPR028364Ribosomal protein uL1/ribosomal biogenesis proteinFamily
G [auth 3G],
H [auth 3H]
IPR002415H/ACA ribonucleoprotein complex, subunit Nhp2-likeFamily
G [auth 3G],
H [auth 3H]
IPR029064Ribosomal protein eL30-like superfamilyHomologous Superfamily
G [auth 3G],
H [auth 3H]
IPR018492Ribosomal protein eL8/Nhp2 familyFamily
G [auth 3G],
H [auth 3H]
IPR004038Ribosomal protein eL8/eL30/eS12/Gadd45Domain
G [auth 3G],
H [auth 3H]
IPR004037Large ribosomal subunit protein eL8-like, conserved siteConserved Site