5WYG
The crystal structure of the apo form of Mtb MazF
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | Kid/PemK | 8076070 | 4002619 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | Cell growth inhibitor/plasmid maintenance toxic component | 8076071 | 3000352 | SCOP2 (2022-06-29) |
B [auth C] | SCOP2B Superfamily | Cell growth inhibitor/plasmid maintenance toxic component | 8076071 | 3000352 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF02452 | e5wygA1 | A: beta barrels | X: SH3 | H: SH3 | T: SH3 | F: PF02452 | ECOD (1.6) |
B [auth C] | PF02452 | e5wygC1 | A: beta barrels | X: SH3 | H: SH3 | T: SH3 | F: PF02452 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth C] | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system (PemK_toxin) | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B [auth C] | IPR011067 | Plasmid maintenance toxin/Cell growth inhibitor | Homologous Superfamily |
A, B [auth C] | IPR003477 | mRNA interferase PemK-like | Family |