Annotations: 5WP5

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF13649	e5wp5A2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF13649	ECOD (1.6)
A	PF13847	e5wp5A1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF13847	ECOD (1.6)
B	PF13649	e5wp5B2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF13649	ECOD (1.6)
B	PF13847	e5wp5B1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: PF13847	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF13847	Methyltransferase domain (Methyltransf_31)	Methyltransferase domain	This family appears to have methyltransferase activity.	Domain
A, B	PF13649	Methyltransferase domain (Methyltransf_25)	Methyltransferase domain	This family appears to be a methyltransferase domain.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Phosphomethylethanolamine N-methyltransferase 2	phosphoethanolamine N-methyltransferase activity transferase activity, transferring one-carbon groups N-methyltransferase activity transferase activity methyltransferase activity catalytic activity S-adenosylmethionine-dependent methyltransferase activity phosphomethylethanolamine N-methyltransferase activity RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding	methylation metabolic process cellular biosynthetic process glycerophospholipid metabolic process organonitrogen compound biosynthetic process lipid biosynthetic process phospholipid metabolic process organic substance metabolic process phosphate-containing compound metabolic process organic substance biosynthetic process phosphatidylcholine metabolic process phosphorus metabolic process organonitrogen compound metabolic process glycerophospholipid biosynthetic process methylation metabolic process cellular biosynthetic process glycerophospholipid metabolic process organonitrogen compound biosynthetic process lipid biosynthetic process phospholipid metabolic process organic substance metabolic process phosphate-containing compound metabolic process organic substance biosynthetic process phosphatidylcholine metabolic process phosphorus metabolic process organonitrogen compound metabolic process glycerophospholipid biosynthetic process cellular metabolic process primary metabolic process phospholipid biosynthetic process biosynthetic process glycerolipid biosynthetic process organophosphate metabolic process organophosphate biosynthetic process cellular lipid metabolic process glycerolipid metabolic process cellular process phosphatidylcholine biosynthetic process lipid metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR025714	Methyltransferase domain	Domain
A, B	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Homologous Superfamily
A, B	IPR025771	Phosphoethanolamine N-methyltransferase	Family
A, B	IPR041698	Methyltransferase domain 25	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.