Annotations: 5WOY

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05524	e5woyA2	A: alpha arrays	X: Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain (From Topology)	H: Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain (From Topology)	T: Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain	F: PF05524	ECOD (1.6)
A	PF00391	e5woyA1	A: a/b three-layered sandwiches	X: The swivelling beta/beta/alpha domains	H: The swivelling beta/beta/alpha domain (From Topology)	T: The swivelling beta/beta/alpha domain	F: PF00391	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.50.30.10	Alpha Beta	3-Layer(bba) Sandwich	Glucose Oxidase	domain 1	CATH (4.3.0)
A	1.10.274.10	Mainly Alpha	Orthogonal Bundle	Enzyme I	Chain A, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00391	PEP-utilising enzyme, mobile domain (PEP-utilizers)	PEP-utilising enzyme, mobile domain	This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.	Domain
A	PF05524	PEP-utilising enzyme, N-terminal (PEP-utilisers_N)	PEP-utilising enzyme, N-terminal	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Phosphoenolpyruvate-protein phosphotransferase	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups phosphoenolpyruvate-protein phosphotransferase activity phosphotransferase activity, nitrogenous group as acceptor cation binding ion binding binding metal ion binding small molecule binding	import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization cellular process carbohydrate transmembrane transport phosphorylation cellular metabolic process import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization cellular process carbohydrate transmembrane transport phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process phosphorus metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR015813	Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily	Homologous Superfamily
A	IPR008279	PEP-utilising enzyme, mobile domain	Domain
A	IPR018274	PEP-utilising enzyme, active site	Active Site
A	IPR036618	PtsI, HPr-binding domain superfamily	Homologous Superfamily
A	IPR006318	Phosphotransferase system, enzyme I-like	Domain
A	IPR023151	PEP-utilising enzyme, conserved site	Conserved Site
A	IPR036637	Phosphohistidine domain superfamily	Homologous Superfamily
A	IPR040442	Pyruvate kinase-like domain superfamily	Homologous Superfamily
A	IPR008731	Phosphotransferase system, enzyme I N-terminal	Domain
A	IPR024692	Phosphotransferase system, enzyme I	Family
A	IPR000121	PEP-utilising enzyme, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.