5VRD

Crystal structure for Methylobacterium extorquens PqqCD (natural fusion)

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth D]	SCOP2B Superfamily	Heme oxygenase-like	8079383	3001676	SCOP2B (2022-06-29)
B [auth A]	SCOP2B Superfamily	Heme oxygenase-like	8079383	3001676	SCOP2B (2022-06-29)
C [auth B]	SCOP2 Family	PqqC-like	8079382	4000768	SCOP2 (2022-06-29)
C [auth B]	SCOP2 Superfamily	Heme oxygenase-like	8079383	3001676	SCOP2 (2022-06-29)
D [auth C]	SCOP2B Superfamily	Heme oxygenase-like	8079383	3001676	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth D]	PF03070	e5vrdD1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Heme oxygenase/Ribonucleotide reductase	F: PF03070	ECOD (1.6)
B [auth A]	PF03070	e5vrdA1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Heme oxygenase/Ribonucleotide reductase	F: PF03070	ECOD (1.6)
C [auth B]	PF03070	e5vrdB1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Heme oxygenase/Ribonucleotide reductase	F: PF03070	ECOD (1.6)
D [auth C]	PF03070	e5vrdC1	A: alpha bundles	X: Ferritin/Heme oxygenase/4-helical cytokines	H: Ferritin/Heme oxygenase	T: Heme oxygenase/Ribonucleotide reductase	F: PF03070	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth D]	1.20.910.10	Mainly Alpha	Up-down Bundle	Heme Oxygenase	Chain A	CATH (utative)
B [auth A]	1.20.910.10	Mainly Alpha	Up-down Bundle	Heme Oxygenase	Chain A	CATH (utative)
C [auth B]	1.20.910.10	Mainly Alpha	Up-down Bundle	Heme Oxygenase	Chain A	CATH (utative)
D [auth C]	1.20.910.10	Mainly Alpha	Up-down Bundle	Heme Oxygenase	Chain A	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D], B [auth A], C [auth B], D [auth C]	PF03070	TENA/THI-4/PQQC family (TENA_THI-4)	TENA/THI-4/PQQC family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D], B [auth A], C [auth B], D [auth C]	Bifunctional coenzyme PQQ synthesis protein C/D	pyrroloquinoline-quinone synthase activity oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors catalytic activity oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor binding quinone binding small molecule binding	pyrroloquinoline quinone biosynthetic process oxoacid metabolic process cellular biosynthetic process organonitrogen compound biosynthetic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process organic substance metabolic process cellular ketone metabolic process organic substance biosynthetic process small molecule metabolic process tricarboxylic acid biosynthetic process organonitrogen compound metabolic process tricarboxylic acid metabolic process pyrroloquinoline quinone biosynthetic process oxoacid metabolic process cellular biosynthetic process organonitrogen compound biosynthetic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process organic substance metabolic process cellular ketone metabolic process organic substance biosynthetic process small molecule metabolic process tricarboxylic acid biosynthetic process organonitrogen compound metabolic process tricarboxylic acid metabolic process small molecule biosynthetic process cellular metabolic process carboxylic acid metabolic process organic cyclic compound metabolic process biosynthetic process organic cyclic compound biosynthetic process metabolic process cellular process ketone biosynthetic process sulfur compound metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D], B [auth A], C [auth B], D [auth C]	IPR004305	Thiaminase-2/PQQC	Domain
A [auth D], B [auth A], C [auth B], D [auth C]	IPR039068	Pyrroloquinoline-quinone synthase-like	Family
A [auth D], B [auth A], C [auth B], D [auth C]	IPR022479	Coenzyme PQQ synthesis D, bacteria	Family
A [auth D], B [auth A], C [auth B], D [auth C]	IPR008792	Coenzyme PQQ synthesis protein D	Family
A [auth D], B [auth A], C [auth B], D [auth C]	IPR041881	Coenzyme PQQ synthesis protein D superfamily	Homologous Superfamily
A [auth D], B [auth A], C [auth B], D [auth C]	IPR011845	Coenzyme PQQ biosynthesis protein C	Family
A [auth D], B [auth A], C [auth B], D [auth C]	IPR016084	Haem oxygenase-like, multi-helical	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.