Annotations: 5UKV

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00512	e5ukvA1	A: alpha duplicates or obligate multimers	X: ROP-like	H: Homodimeric domain of signal transducing histidine kinase (From Topology)	T: Homodimeric domain of signal transducing histidine kinase	F: PF00512	ECOD (1.6)
B	PF00512	e5ukvB1	A: alpha duplicates or obligate multimers	X: ROP-like	H: Homodimeric domain of signal transducing histidine kinase (From Topology)	T: Homodimeric domain of signal transducing histidine kinase	F: PF00512	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B	PF00512	His Kinase A (phospho-acceptor) domain (HisKA)	His Kinase A (phospho-acceptor) domain	Dimerisation and phospho-acceptor domain of histidine kinases.	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	ATP-binding protein	catalytic activity, acting on a protein small molecule sensor activity kinase activity protein kinase activity transferase activity phosphotransferase activity, nitrogenous group as acceptor phosphotransferase activity, alcohol group as acceptor protein histidine kinase activity transferase activity, transferring phosphorus-containing groups phosphorelay sensor kinase activity catalytic activity	cellular response to stimulus regulation of biological process phosphorelay signal transduction system regulation of cellular process response to stimulus signaling biological regulation intracellular signal transduction cell communication cellular process signal transduction	cell periphery plasma membrane membrane cellular anatomical entity

Chains	Accession	Name	Type
A, B	IPR005467	Histidine kinase domain	Domain
A, B	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	Domain
A, B	IPR003594	Histidine kinase/HSP90-like ATPase	Domain
A, B	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	Homologous Superfamily
A, B	IPR003660	HAMP domain	Domain
A, B	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	Homologous Superfamily
A, B	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	Domain