5UE7

Crystal structure of the phosphomannomutase PMM1 from Candida albicans, apoenzyme state

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5ue7a_	Alpha and beta proteins (a/b)	HAD-like	HAD-like	automated matches	automated matches	Yeast (Candida albicans SC5314 ) [TaxId: 237561 ],	SCOPe (2.08)
B	d5ue7b_	Alpha and beta proteins (a/b)	HAD-like	HAD-like	automated matches	automated matches	Yeast (Candida albicans SC5314 ) [TaxId: 237561 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Predicted hydrolases Cof	8062650	4002994	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	HAD-like	8062651	3001890	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	HAD-like	8062651	3001890	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03332	e5ue7A2	A: a+b two layers	X: Cof C2 cap domain (From Topology)	H: Cof C2 cap domain (From Topology)	T: Cof C2 cap domain	F: PF03332	ECOD (1.6)
A	PF03332	e5ue7A1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: PF03332	ECOD (1.6)
B	PF03332	e5ue7B2	A: a+b two layers	X: Cof C2 cap domain (From Topology)	H: Cof C2 cap domain (From Topology)	T: Cof C2 cap domain	F: PF03332	ECOD (1.6)
B	PF03332	e5ue7B1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: HAD-like	F: PF03332	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
A	3.30.1240.20	Alpha Beta	2-Layer Sandwich	Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase	Chain: A	CATH (4.3.0)
B	3.40.50.1000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HAD superfamily/HAD-like	CATH (4.3.0)
B	3.30.1240.20	Alpha Beta	2-Layer Sandwich	Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03332	Eukaryotic phosphomannomutase (PMM)	Eukaryotic phosphomannomutase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Phosphomannomutase	isomerase activity intramolecular phosphotransferase activity catalytic activity phosphomannomutase activity intramolecular transferase activity cation binding ion binding binding metal ion binding small molecule binding	cellular biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process organic substance metabolic process organic substance biosynthetic process protein metabolic process protein modification process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process cellular metabolic process glycoprotein biosynthetic process primary metabolic process glycoprotein metabolic process protein N-linked glycosylation cellular biosynthetic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process organic substance metabolic process organic substance biosynthetic process protein metabolic process protein modification process carbohydrate derivative biosynthetic process organonitrogen compound metabolic process cellular metabolic process glycoprotein biosynthetic process primary metabolic process glycoprotein metabolic process protein N-linked glycosylation protein glycosylation macromolecule biosynthetic process biosynthetic process glycosylation macromolecule modification macromolecule glycosylation metabolic process cellular process macromolecule metabolic process monosaccharide metabolic process carbohydrate metabolic process mannose metabolic process hexose metabolic process small molecule metabolic process nucleotide-sugar metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process nucleobase-containing small molecule metabolic process organic cyclic compound biosynthetic process GDP-mannose biosynthetic process nucleotide-sugar biosynthetic process GDP-mannose metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cell periphery extracellular matrix biofilm matrix external encapsulating structure fungal biofilm matrix

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036412	HAD-like superfamily	Homologous Superfamily
A, B	IPR023214	HAD superfamily	Homologous Superfamily
A, B	IPR005002	Phosphomannomutase	Family
A, B	IPR006379	HAD-superfamily hydrolase, subfamily IIB	Family
A, B	IPR043169	Phosphomannomutase, cap domain	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.