5U9O

Cocrystal structure of the intermembrane space region of the plastid division proteins PARC6 and PDV1

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF13355	e5u9oA1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
B	PF13355	e5u9oB1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
C	PF13355	e5u9oC1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
D	PF13355	e5u9oD1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
E	PF13355	e5u9oE1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
F	PF13355	e5u9oF1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
G	PF13355	e5u9oG1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)
H	PF13355	e5u9oH1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: PF13355	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF13355	ARC6-like, IMS domain (ARC6-like_IMS)	ARC6-like, IMS domain	This domain corresponds to the C-terminal intermembrane space (IMS) region from protein accumulation and replication of chloroplasts 6 (ARC6) and its paralogue PARC6 [1]. ARC6 and PARC6 are components of the plastid division machinery which are essen ...	This domain corresponds to the C-terminal intermembrane space (IMS) region from protein accumulation and replication of chloroplasts 6 (ARC6) and its paralogue PARC6 [1]. ARC6 and PARC6 are components of the plastid division machinery which are essential for the chloroplast replication process [1,2], which implies the assembly and constriction of the tubulin-like FtsZ ring on the stromal surface of the inner envelope membrane (IEM) and the dynamin-like ARC5 ring on the cytosolic surface of the outer envelope membrane (OEM). ARC6 is evolutionarily related to the cyanobacterial cell division protein Ftn2/ZipN [1], having similar structures. This domain from ARC6 and PARC6 interacts with PDV2 and PDV1 respectively. PDV proteins recruit dynamin-like ARC5 ring to the chloroplast surface and mediates its constriction. ARC6/PARC6 are key to connect and coordinate Fst and ARC5 rings during fission [3,4].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Plastid division protein CDP1, chloroplastic,Plastid division protein PDV1	binding phospholipid binding lipid binding phosphatidylinositol phosphate binding phosphatidylinositol-4-phosphate binding phosphatidylinositol binding	response to gibberellin response to organic substance response to lipid response to stimulus response to hormone response to chemical response to endogenous stimulus response to oxygen-containing compound chloroplast fission cellular component organization organelle organization plastid organization chloroplast organization organelle fission response to gibberellin response to organic substance response to lipid response to stimulus response to hormone response to chemical response to endogenous stimulus response to oxygen-containing compound chloroplast fission cellular component organization organelle organization plastid organization chloroplast organization organelle fission cellular process cellular component organization or biogenesis plastid fission	membrane-bounded organelle plastid membrane intracellular anatomical structure plastid membrane chloroplast envelope organelle outer membrane cellular anatomical entity intracellular membrane-bounded organelle plastid outer membrane chloroplast outer membrane intracellular organelle organelle envelope bounding membrane of organelle membrane-bounded organelle plastid membrane intracellular anatomical structure plastid membrane chloroplast envelope organelle outer membrane cellular anatomical entity intracellular membrane-bounded organelle plastid outer membrane chloroplast outer membrane intracellular organelle organelle envelope bounding membrane of organelle chloroplast membrane organelle outer membrane cytoplasm organelle membrane plastid envelope chloroplast organelle inner membrane plastid inner membrane chloroplast inner membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR038939	Plastid division protein PDV1/PDV2	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR044685	Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6-like	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR025344	ARC6, IMS domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.