5U68
Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
D [auth E] | d5u68e1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
E [auth F] | d5u68f1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
F [auth G] | d5u68g1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00523 | e5u68A1 | A: a+b complex topology | X: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology) | H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology) | T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein | F: PF00523 | ECOD (1.6) |
B | PF00523 | e5u68B1 | A: a+b complex topology | X: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology) | H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology) | T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein | F: PF00523 | ECOD (1.6) |
C | PF00523 | e5u68C1 | A: a+b complex topology | X: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology) | H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology) | T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein | F: PF00523 | ECOD (1.6) |
D [auth E] | PF07686 | e5u68E2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
E [auth F] | PF07686 | e5u68F1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
F [auth G] | PF07686 | e5u68G1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
D [auth E] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
E [auth F] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
F [auth G] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
D [auth E], E [auth F], F [auth G] | scFv MPE8, anti-RSV F, neutralizing | SCFV-HEAVY-LAMBDA | Homo sapiens (human) | IGHV3-21*01, IGHV3-21*02, IGHV3-21*04, IGHV3-21*03, IGHJ4*01, IGHJ4*02, IGHJ4*03, IGLV1-40*02, IGLJ1*01 | V-DOMAIN VH, V-DOMAIN V-LAMBDA | IG | SCFV-HEAVY-LAMBDA | IMGT (202416-0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00523 | Fusion glycoprotein F0 (Fusion_gly) | Fusion glycoprotein F0 | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR012473 | Fibritin C-terminal | Domain | |
IPR000776 | Precursor fusion glycoprotein F0, Paramyxoviridae | Family |