Annotations: 5U07

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF08798	e5u07A1	A: a+b two layers	X: Alpha-beta plaits	H: CRISPR transcript (pre-crRNA) processing endoribonuclease-related (From Topology)	T: CRISPR transcript (pre-crRNA) processing endoribonuclease-related	F: PF08798	ECOD (1.6)
B	PF09485	e5u07B1	A: alpha bundles	X: CRISPR-associated protein Cse2 (From Topology)	H: CRISPR-associated protein Cse2 (From Topology)	T: CRISPR-associated protein Cse2	F: PF09485	ECOD (1.6)
J	PF09485	e5u07J1	A: alpha bundles	X: CRISPR-associated protein Cse2 (From Topology)	H: CRISPR-associated protein Cse2 (From Topology)	T: CRISPR-associated protein Cse2	F: PF09485	ECOD (1.6)
C	PF09481	e5u07C1	A: a+b complex topology	X: Cas8-like	H: Cascade subunit CasA/Cse1/Cas8 (From Topology)	T: Cascade subunit CasA/Cse1/Cas8	F: PF09481	ECOD (1.6)
D	PF09344	e5u07D1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7/Csa2-related	F: PF09344	ECOD (1.6)
E	PF09344	e5u07E1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7/Csa2-related	F: PF09344	ECOD (1.6)
F	PF09344	e5u07F1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7/Csa2-related	F: PF09344	ECOD (1.6)
G	PF09344	e5u07G1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7/Csa2-related	F: PF09344	ECOD (1.6)
H	PF09344	e5u07H1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7/Csa2-related	F: PF09344	ECOD (1.6)
I	PF09344	e5u07I1	A: a+b two layers	X: Alpha-beta plaits	H: Cas7-related	T: CRISPR-associated protein Cas7/Csa2-related	F: PF09344	ECOD (1.6)
M [auth N]	PF09704	e5u07N1	A: a+b two layers	X: Alpha-beta plaits	H: CRISPR system Cas5 homologs (From Topology)	T: CRISPR system Cas5 homologs	F: PF09704	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF08798	CRISPR associated protein (CRISPR_assoc)	CRISPR associated protein	This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	Domain
B, J	PF09485	CRISPR-associated protein Cse2 (CRISPR_cse2) (CRISPR_Cse2)	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	Family
C	PF09481	CRISPR-associated protein Cse1 (CRISPR_cse1) (CRISPR_Cse1)	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	Family
D, E, F, G, H D, E, F, G, H, I	PF09344	CT1975-like protein (Cas_CT1975)	CT1975-like protein	-	Family
M [auth N]	PF09704	CRISPR-associated protein (Cas_Cas5) (Cas_Cas5d)	CRISPR-associated protein (Cas_Cas5)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CRISPR-associated protein, Cse3 family	-	-	-
B, J	Cse2	identical protein binding protein binding binding	-	-
C	CRISPR-associated protein, Cse1 family	-	-	-
D, E, F, G, H D, E, F, G, H, I	CRISPR-associated protein, Cse4 family	-	-	-
K	crRNA	-	-	-
L [auth M]	Target Strand	-	-	-
M [auth N]	CRISPR-associated protein, Cas5e family	RNA binding binding organic cyclic compound binding nucleic acid binding	biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response defense response to symbiont response to external stimulus response to biotic stimulus defense response to virus defense response to other organism response to stress response to external biotic stimulus response to virus maintenance of CRISPR repeat elements chromosome organization biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response defense response to symbiont response to external stimulus response to biotic stimulus defense response to virus defense response to other organism response to stress response to external biotic stimulus response to virus maintenance of CRISPR repeat elements chromosome organization primary metabolic process DNA metabolic process maintenance of DNA repeat elements nucleic acid metabolic process cellular component organization nucleobase-containing compound metabolic process organic cyclic compound metabolic process organelle organization organic substance metabolic process cellular process metabolic process cellular component organization or biogenesis macromolecule metabolic process	-
N [auth O]	Nontarget Strand	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR010179	CRISPR-associated protein Cse3	Family
B, J	IPR013382	CRISPR-associated protein Cse2	Family
B, J	IPR038287	Cse2 superfamily	Homologous Superfamily
C	IPR013381	CRISPR-associated protein Cse1	Family
D, E, F, G, H D, E, F, G, H, I	IPR010148	CRISPR-associated protein, CT1975	Family
M [auth N]	IPR010147	CRISPR-associated protein, CasD	Family
M [auth N]	IPR021124	CRISPR-associated protein, Cas5	Family
M [auth N]	IPR013422	CRISPR-associated protein Cas5, N-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.