Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
CA [auth l]SCOP2 FamilyRibosomal protein S108099461 4001240 SCOP2 (2022-06-29)
CA [auth l]SCOP2 SuperfamilyRibosomal protein S108099462 3001336 SCOP2 (2022-06-29)
A [auth p]SCOP2 FamilyWD40-repeat8101626 4002744 SCOP2 (2022-06-29)
A [auth p]SCOP2 SuperfamilyWD40 repeat-like8101627 3001694 SCOP2 (2022-06-29)
L [auth T]SCOP2 FamilyRibosomal protein S26e8059225 4006236 SCOP2 (2022-06-29)
L [auth T]SCOP2 SuperfamilyGlucocorticoid receptor-like (DNA-binding domain)8059226 3000068 SCOP2 (2022-06-29)
M [auth U]SCOP2 FamilyCold shock DNA-binding domain-like8063427 4001909 SCOP2 (2022-06-29)
M [auth U]SCOP2 SuperfamilyNucleic acid-binding proteins8063428 3000135 SCOP2 (2022-06-29)
N [auth V]SCOP2 FamilyRibosomal protein L18p and S118099463 4000555 SCOP2 (2022-06-29)
N [auth V]SCOP2 SuperfamilyTranslational machinery components8099464 3000571 SCOP2 (2022-06-29)
O [auth W]SCOP2 FamilyRibosomal S3Ae8059221 4006095 SCOP2 (2022-06-29)
O [auth W]SCOP2 SuperfamilyRibosomal S3Ae-like8059222 3002166 SCOP2 (2022-06-29)
T [auth f]SCOP2 FamilyRibosomal protein S2-like8099455 4003744 SCOP2 (2022-06-29)
T [auth f]SCOP2 SuperfamilySIS domain/Ribosomal protein S2-like8099456 3001397 SCOP2 (2022-06-29)
V [auth e]SCOP2 FamilyRibosomal protein S88099479 4002027 SCOP2 (2022-06-29)
V [auth e]SCOP2 SuperfamilyRibosomal protein S88099480 3000709 SCOP2 (2022-06-29)
W [auth g]SCOP2 FamilyRibosomal protein S21e8099483 4006215 SCOP2 (2022-06-29)
W [auth g]SCOP2 SuperfamilyGlucocorticoid receptor-like (DNA-binding domain)8099484 3000068 SCOP2 (2022-06-29)
X [auth a]SCOP2 FamilyRibosomal protein S25-like8099473 4007308 SCOP2 (2022-06-29)
X [auth a]SCOP2 SuperfamilyWinged helix DNA-binding domain8099474 3000034 SCOP2 (2022-06-29)
Y [auth i]SCOP2 FamilyL30e/L7ae ribosomal proteins8099459 4001513 SCOP2 (2022-06-29)
Y [auth i]SCOP2 SuperfamilyL30e-like8099460 3001739 SCOP2 (2022-06-29)
C [auth r]SCOP2 FamilyTranslational machinery components8099469 4000951 SCOP2 (2022-06-29)
C [auth r]SCOP2 SuperfamilyRibosomal protein S5 domain 2-like8099470 3000100 SCOP2 (2022-06-29)
EA [auth n]SCOP2 FamilyeS10-like8099477 4007434 SCOP2 (2022-06-29)
EA [auth n]SCOP2 SuperfamilyWinged helix DNA-binding domain8099478 3000034 SCOP2 (2022-06-29)
FA [auth o]SCOP2 FamilyRps19E-like8099471 4000222 SCOP2 (2022-06-29)
FA [auth o]SCOP2 SuperfamilyWinged helix DNA-binding domain8099472 3000034 SCOP2 (2022-06-29)
GA [auth c]SCOP2 FamilyRibosomal protein S30e-like8099465 4005067 SCOP2 (2022-06-29)
GA [auth c]SCOP2 SuperfamilyRibosomal protein S30e-like8099466 3002190 SCOP2 (2022-06-29)
E [auth u]SCOP2 FamilyRibosomal protein S138101628 4000260 SCOP2 (2022-06-29)
E [auth u]SCOP2 SuperfamilyS13-like H2TH domain8101629 3000053 SCOP2 (2022-06-29)
H [auth O]SCOP2 FamilyRibosomal protein S78066022 4001112 SCOP2 (2022-06-29)
H [auth O]SCOP2 SuperfamilyRibosomal protein S78066023 3000799 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
CA [auth l]PF00338e5optl1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal protein S10 (From Topology)T: Ribosomal protein S10F: PF00338ECOD (1.6)
A [auth p]PF00400e5optp1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
J [auth R]PF08069e5optR1 A: alpha arraysX: HTHH: 40S ribosomal protein S13 N-terminal domain (From Topology)T: 40S ribosomal protein S13 N-terminal domainF: PF08069ECOD (1.6)
J [auth R]PF00312e5optR2 A: alpha arraysX: S15/NS1 RNA-binding domain (From Topology)H: S15/NS1 RNA-binding domain (From Topology)T: S15/NS1 RNA-binding domainF: PF00312ECOD (1.6)
K [auth S]PF01667e5optS1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: PF01667ECOD (1.6)
L [auth T]PF01283e5optT1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: LIM domain-likeF: PF01283ECOD (1.6)
M [auth U]PF01200e5optU1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF01200ECOD (1.6)
N [auth V]PF00411e5optV1 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: PF00411ECOD (1.6)
O [auth W]PF01015e5optW2 A: beta barrelsX: Ribosomal protein L25-likeH: 40S ribosomal protein S3A N-terminal domain (From Topology)T: 40S ribosomal protein S3A N-terminal domainF: PF01015ECOD (1.6)
O [auth W]PF01015e5optW1 A: a+b two layersX: T-foldH: 40S ribosomal protein S3A C-terminal domain (From Topology)T: 40S ribosomal protein S3A C-terminal domainF: PF01015ECOD (1.6)
P [auth X]PF00366,PF16205e5optX1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF00366,PF16205ECOD (1.6)
Q [auth Y]PF01282e5optY1 A: a+b two layersX: Alpha-beta plaitsH: Ribosomal proteins S24e, L23 and L15e (From Topology)T: Ribosomal proteins S24e, L23 and L15eF: PF01282ECOD (1.6)
R [auth Z]PF01201e5optZ1 A: beta barrelsX: Ribosomal protein L14-likeH: Ribosomal protein L14-related (From Topology)T: Ribosomal protein L14-relatedF: PF01201ECOD (1.6)
S [auth b]PF00163,PF01479e5optb1 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: PF00163,PF01479ECOD (1.6)
B [auth q]PF00253e5optq1 A: few secondary structure elementsX: Glucocorticoid receptor-likeH: LIM domain-likeT: LIM domain-likeF: PF00253ECOD (1.6)
T [auth f]PF00318e5optf1 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Ribosomal protein S2/SIS domain (From Topology)T: Ribosomal protein S2/SIS domainF: PF00318ECOD (1.6)
U [auth d]PF03719e5optd1 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: PF03719ECOD (1.6)
U [auth d]PF00333e5optd3 A: a+b two layersX: dsRBD-likeH: dsRNA-binding domain-like (From Topology)T: dsRNA-binding domain-likeF: PF00333ECOD (1.6)
U [auth d]PF00333e5optd2 A: extended segmentsX: N-terminal region in 40S ribosomal protein rpS2 (S5p) (From Topology)H: N-terminal region in 40S ribosomal protein rpS2 (S5p) (From Topology)T: N-terminal region in 40S ribosomal protein rpS2 (S5p)F: PF00333ECOD (1.6)
V [auth e]PF00410e5opte2 A: a+b two layersX: R3H domain-likeH: Ribosomal protein S8, N-terminal domain (From Topology)T: Ribosomal protein S8, N-terminal domainF: PF00410ECOD (1.6)
V [auth e]PF00410e5opte1 A: a+b two layersX: Ribosomal protein S8, C-terminal domain (From Topology)H: Ribosomal protein S8, C-terminal domain (From Topology)T: Ribosomal protein S8, C-terminal domainF: PF00410ECOD (1.6)
W [auth g]PF01249e5optg1 A: a+b two layersX: 40S ribosomal protein rpS21 (S21e) (From Topology)H: 40S ribosomal protein rpS21 (S21e) (From Topology)T: 40S ribosomal protein rpS21 (S21e)F: PF01249ECOD (1.6)
X [auth a]PF03297e5opta1 A: alpha arraysX: HTHH: HTHT: wingedF: PF03297ECOD (1.6)
Y [auth i]PF01248e5opti1 A: a+b three layersX: Bacillus chorismate mutase-likeH: L30e-like (From Topology)T: L30e-likeF: PF01248ECOD (1.6)
Z [auth j]PF01599e5optj1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: PF01599ECOD (1.6)
AA [auth P]PF01092e5optP1 A: beta barrelsX: Ribosomal protein L25-likeH: Ribosomal protein L25-like (From Topology)T: Ribosomal protein L25-likeF: PF01092ECOD (1.6)
BA [auth k]PF00833e5optk1 A: alpha arraysX: HTHH: HTHT: FF domainF: PF00833ECOD (1.6)
C [auth r]PF00380e5optr1 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: PF00380ECOD (1.6)
DA [auth m]PF00189e5optm1 A: a+b two layersX: T-foldH: Ribosomal protein S3-C (From Topology)T: Ribosomal protein S3-CF: PF00189ECOD (1.6)
DA [auth m]PF07650e5optm2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: KH-domainsT: Prokaryotic type KH domain (KH-domain type II)F: PF07650ECOD (1.6)
EA [auth n]PF03501e5optn1 A: alpha arraysX: HTHH: HTHT: wingedF: PF03501ECOD (1.6)
FA [auth o]PF01090e5opto1 A: alpha arraysX: HTHH: HTHT: wingedF: PF01090ECOD (1.6)
GA [auth c]PF04758e5optc1 A: extended segmentsX: 40S ribosomal protein S30 (S30e) (From Topology)H: 40S ribosomal protein S30 (S30e) (From Topology)T: 40S ribosomal protein S30 (S30e)F: PF04758ECOD (1.6)
HA [auth h]F_UNCLASSIFIEDe5opth3 A: a+b two layersX: Alpha-beta plaitsH: RNA-binding domain, RBD (From Topology)T: RNA-binding domain, RBDF: F_UNCLASSIFIEDECOD (1.6)
HA [auth h]PF00076e5opth2 A: a+b two layersX: Alpha-beta plaitsH: RNA-binding domain, RBD (From Topology)T: RNA-binding domain, RBDF: PF00076ECOD (1.6)
D [auth t]PF00203e5optt1 A: a+b two layersX: Ribosomal protein S19 (From Topology)H: Ribosomal protein S19 (From Topology)T: Ribosomal protein S19F: PF00203ECOD (1.6)
E [auth u]PF00416e5optu1 A: alpha arraysX: HhH/H2THH: H2TH (From Topology)T: H2THF: PF00416ECOD (1.6)
F [auth L]PF00900e5optL1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF00900ECOD (1.6)
F [auth L]PF00467,PF16121e5optL3 A: beta barrelsX: SH3H: SH3T: SH3F: PF00467,PF16121ECOD (1.6)
F [auth L]PF01479,PF08071e5optL2 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Alpha-L RNA-binding motifF: PF01479,PF08071ECOD (1.6)
G [auth M]PF00164e5optM1 A: beta barrelsX: OB-foldH: Nucleic acid-binding proteins (From Topology)T: Nucleic acid-binding proteinsF: PF00164ECOD (1.6)
H [auth O]PF00177e5optO1 A: alpha arraysX: Ribosomal protein S7 (From Topology)H: Ribosomal protein S7 (From Topology)T: Ribosomal protein S7F: PF00177ECOD (1.6)
I [auth Q]PF01251e5optQ1 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: 40S ribosomal protein S7-A (From Topology)T: 40S ribosomal protein S7-AF: PF01251ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
CA [auth l]3.30.70.600 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Ribosomal protein S10CATH (4.3.0)
A [auth p]2.130.10.10 Mainly Beta 7 Propeller Methylamine Dehydrogenase Chain HCATH (4.3.0)
J [auth R]1.10.287.10 Mainly Alpha Orthogonal Bundle Helix Hairpins S15/NS1, RNA-bindingCATH (4.3.0)
K [auth S]2.20.25.100 Mainly Beta Single Sheet N-terminal domain of TfIIb Ribosomal protein S27CATH (4.3.0)
L [auth T]3.30.1740.20 Alpha Beta 2-Layer Sandwich first zn-finger domain of poly(adp-ribose) polymerase-1 Ribosomal protein S26CATH (4.3.0)
M [auth U]2.40.50.140 Mainly Beta Beta Barrel OB fold (Dihydrolipoamide Acetyltransferase, E2P) Nucleic acid-binding proteinsCATH (4.3.0)
N [auth V]3.30.420.80 Alpha Beta 2-Layer Sandwich Nucleotidyltransferase domain 5CATH (4.3.0)
P [auth X]2.40.50.1000 Mainly Beta Beta Barrel OB fold (Dihydrolipoamide Acetyltransferase, E2P) CATH (4.3.0)
Q [auth Y]3.30.70.3370 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits CATH (4.3.0)
T [auth f]3.40.50.10490 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Glucose-6-phosphate isomerase like proteinCATH (4.3.0)
U [auth d]3.30.160.20 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain CATH (4.3.0)
U [auth d]3.30.230.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5 domain 2CATH (4.3.0)
V [auth e]3.30.1370.30 Alpha Beta 2-Layer Sandwich Ribosomal Protein S8 Chain: A, domain 1CATH (4.3.0)
V [auth e]3.30.1490.10 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)
W [auth g]3.30.1230.20 Alpha Beta 2-Layer Sandwich Hypothetical Cytosolic Protein Chain: ACATH (4.3.0)
Y [auth i]3.30.1330.30 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30 Chain: ACATH (4.3.0)
BA [auth k]1.10.60.20 Mainly Alpha Orthogonal Bundle Diphtheria Toxin Repressor domain 2CATH (4.3.0)
C [auth r]3.30.230.10 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5 domain 2CATH (4.3.0)
DA [auth m]3.30.300.20 Alpha Beta 2-Layer Sandwich GMP Synthetase Chain A, domain 3CATH (4.3.0)
DA [auth m]3.30.1140.32 Alpha Beta 2-Layer Sandwich Ribosomal protein S3 C-terminal domain Ribosomal protein S3, C-terminal domainCATH (4.3.0)
EA [auth n]1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
F [auth L]3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region Chain ACATH (4.3.0)
F [auth L]2.40.50.740 Mainly Beta Beta Barrel OB fold (Dihydrolipoamide Acetyltransferase, E2P) Ribosomal protein S4, central domainCATH (4.3.0)
F [auth L]2.30.30.30 Mainly Beta Roll SH3 type barrels. CATH (4.3.0)
H [auth O]1.10.455.10 Mainly Alpha Orthogonal Bundle Ribosomal Protein S7 Ribosomal protein S7/S5CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
CA [auth l]PF00338Ribosomal protein S10p/S20e (Ribosomal_S10)Ribosomal protein S10p/S20eThis family includes small ribosomal subunit S10 from prokaryotes and S20 from eukaryotes.Domain
A [auth p]PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
J [auth R]PF08069Ribosomal S13/S15 N-terminal domain (Ribosomal_S13_N)Ribosomal S13/S15 N-terminal domainThis domain is found at the N-terminus of ribosomal S13 and S15 proteins. This domain is also identified as NUC021 [1].Domain
J [auth R]PF00312Ribosomal protein S15 (Ribosomal_S15)Ribosomal protein S15- Domain
K [auth S]PF01667Ribosomal protein S27 (Ribosomal_S27e)Ribosomal protein S27- Family
L [auth T]PF01283Ribosomal protein S26e (Ribosomal_S26e)Ribosomal protein S26e- Family
M [auth U]PF01200Ribosomal protein S28e (Ribosomal_S28e)Ribosomal protein S28e- Family
N [auth V]PF00411Ribosomal protein S11 (Ribosomal_S11)Ribosomal protein S11- Family
O [auth W]PF01015Ribosomal S3Ae family (Ribosomal_S3Ae)Ribosomal S3Ae family- Family
P [auth X]PF00366Ribosomal protein S17 (Ribosomal_S17)Ribosomal protein S17- Domain
P [auth X]PF16205Ribosomal_S17 N-terminal (Ribosomal_S17_N)Ribosomal_S17 N-terminal- Family
Q [auth Y]PF01282Ribosomal protein S24e (Ribosomal_S24e)Ribosomal protein S24e- Family
R [auth Z]PF01201Ribosomal protein S8e (Ribosomal_S8e)Ribosomal protein S8e- Family
S [auth b]PF00163Ribosomal protein S4/S9 N-terminal domain (Ribosomal_S4)Ribosomal protein S4/S9 N-terminal domain- Family
S [auth b]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
B [auth q]PF00253Ribosomal protein S14p/S29e (Ribosomal_S14)Ribosomal protein S14p/S29e- Family
T [auth f]PF00318Ribosomal protein S2 (Ribosomal_S2)Ribosomal protein S2- Family
U [auth d]PF03719Ribosomal protein S5, C-terminal domain (Ribosomal_S5_C)Ribosomal protein S5, C-terminal domain- Domain
U [auth d]PF00333Ribosomal protein S5, N-terminal domain (Ribosomal_S5)Ribosomal protein S5, N-terminal domain- Domain
V [auth e]PF00410Ribosomal protein S8 (Ribosomal_S8)Ribosomal protein S8- Domain
W [auth g]PF01249Ribosomal protein S21e (Ribosomal_S21e)Ribosomal protein S21e- Family
X [auth a]PF03297S25 ribosomal protein (Ribosomal_S25)S25 ribosomal protein- Family
Y [auth i]PF01248Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)Ribosomal protein L7Ae/L30e/S12e/Gadd45 familyThis family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].
Domain
Z [auth j]PF01599Ribosomal protein S27a (Ribosomal_S27)Ribosomal protein S27aThis family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins ...This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesised as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis [3]. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins [2].
Domain
AA [auth P]PF01092Ribosomal protein S6e (Ribosomal_S6e)Ribosomal protein S6e- Family
BA [auth k]PF00833Ribosomal S17 (Ribosomal_S17e)Ribosomal S17- Family
C [auth r]PF00380Ribosomal protein S9/S16 (Ribosomal_S9)Ribosomal protein S9/S16- Family
DA [auth m]PF07650KH domain (KH_2)KH domain- Domain
DA [auth m]PF00189Ribosomal protein S3, C-terminal domain (Ribosomal_S3_C)Ribosomal protein S3, C-terminal domainThis family contains a central domain Pfam:PF00013, hence the amino and carboxyl terminal domains are stored separately. This is a minimal carboxyl-terminal domain. Some are much longer.Domain
EA [auth n]PF03501Plectin/S10 domain (S10_plectin)Plectin/S10 domainThis presumed domain is found at the N-terminus of some isoforms of the cytoskeletal muscle protein plectin as well as the ribosomal S10 protein. This domain may be involved in RNA binding.Domain
FA [auth o]PF01090Ribosomal protein S19e (Ribosomal_S19e)Ribosomal protein S19e- Family
GA [auth c]PF04758Ribosomal protein S30 (Ribosomal_S30)Ribosomal protein S30- Family
HA [auth h]PF00076RNA recognition motif (RRM_1)RNA recognition motifThe RRM motif (a.k.a. RRM, RBD, or RNP domain) is probably diagnostic of an RNA binding protein. RRMs are found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regulation of alternative splicing, and pro ...The RRM motif (a.k.a. RRM, RBD, or RNP domain) is probably diagnostic of an RNA binding protein. RRMs are found in a variety of RNA binding proteins, including various hnRNP proteins, proteins implicated in regulation of alternative splicing, and protein components of snRNPs. The motif also appears in a few single stranded DNA binding proteins. The RRM structure consists of four strands and two helices arranged in an alpha/beta sandwich, with a third helix present during RNA binding in some cases The C-terminal beta strand (4th strand) and final helix are hard to align and have been omitted in the SEED alignment The LA proteins (Swiss:P05455) have an N terminal rrm which is included in the seed. There is a second region towards the C terminus that has some features characteristic of a rrm but does not appear to have the important structural core of a rrm. The LA proteins (Swiss:P05455) are one of the main autoantigens in Systemic lupus erythematosus (SLE), an autoimmune disease.
Domain
D [auth t]PF00203Ribosomal protein S19 (Ribosomal_S19)Ribosomal protein S19- Domain
E [auth u]PF00416Ribosomal protein S13/S18 (Ribosomal_S13)Ribosomal protein S13/S18- Family
F [auth L]PF00900Ribosomal family S4e (Ribosomal_S4e)Ribosomal family S4e- Family
F [auth L]PF1612140S ribosomal protein S4 C-terminus (40S_S4_C)40S ribosomal protein S4 C-terminus- Family
F [auth L]PF08071RS4NT (NUC023) domain (RS4NT)RS4NT (NUC023) domainThis is the N-terminal domain of Ribosomal S4 / S4e proteins. This domain is associated with S4 and KOW domains [1].Domain
F [auth L]PF01479S4 domain (S4)S4 domainThe S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast pro ...The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation [1]. The S4 domain probably mediates binding to RNA.
Domain
F [auth L]PF00467KOW motif (KOW)KOW motif- Family
G [auth M]PF00164Ribosomal protein S12/S23 (Ribosom_S12_S23)Ribosomal protein S12/S23- Family
H [auth O]PF00177Ribosomal protein S7p/S5e (Ribosomal_S7)Ribosomal protein S7p/S5eThis family contains ribosomal protein S7 from prokaryotes and S5 from eukaryotes.Domain
I [auth Q]PF01251Ribosomal protein S7e (Ribosomal_S7e)Ribosomal protein S7e- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
CA [auth l]Ribosomal protein S20, putative
A [auth p]Activated protein kinase C receptor, putative
J [auth R]40S ribosomal protein S13, putative
K [auth S]40S ribosomal protein S27, putative
L [auth T]40S ribosomal protein S26
M [auth U]40S ribosomal protein S33, putative
N [auth V]40S ribosomal protein S14, putative
O [auth W]40S ribosomal protein S3a-2
P [auth X]40S ribosomal protein S11, putative
Q [auth Y]40S ribosomal protein S24
R [auth Z]40S ribosomal protein S8
S [auth b]40S ribosomal protein S9, putative
B [auth q]Ribosomal protein S29, putative
T [auth f]40S ribosomal protein SA
U [auth d]40S ribosomal protein S2, putative
V [auth e]40S ribosomal protein S15a, putative
W [auth g]40S ribosomal protein S21, putative
X [auth a]Ribosomal protein S25, putative- -
Y [auth i]40S ribosomal protein S12
Z [auth j]Ubiquitin/ribosomal protein S27a, putative
AA [auth P]40S ribosomal protein S6
BA [auth k]40S ribosomal protein S17, putative
C [auth r]40S ribosomal protein S16, putative
DA [auth m]40S ribosomal protein S3, putative
EA [auth n]40S ribosomal protein S10, putative- -
FA [auth o]Ribosomal protein S19, putative
GA [auth c]40S ribosomal protein S30
HA [auth h]RNA-binding protein, putative - -
IA [auth E]18S rRNA---
D [auth t]40S ribosomal protein S15, putative
E [auth u]40S ribosomal protein S18, putative
F [auth L]40S ribosomal protein S4
G [auth M]40S ribosomal protein S23, putative
H [auth O]40S ribosomal protein S5, putative
I [auth Q]Ribosomal protein S7, putative

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
CA [auth l]IPR001848Small ribosomal subunit protein uS10Family
CA [auth l]IPR027486Small ribosomal subunit protein uS10 domainDomain
CA [auth l]IPR036838Small ribosomal subunit protein uS10 domain superfamilyHomologous Superfamily
CA [auth l]IPR005729Small ribosomal subunit protein uS10, eukaryotic/archaealFamily
A [auth p]IPR045223Small ribosomal subunit protein RACK1-likeFamily
A [auth p]IPR001680WD40 repeatRepeat
A [auth p]IPR019775WD40 repeat, conserved siteConserved Site
A [auth p]IPR020472G-protein beta WD-40 repeatRepeat
A [auth p]IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
A [auth p]IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
J [auth R]IPR012606Small ribosomal subunit protein uS15, N-terminalDomain
J [auth R]IPR009068uS15/NS1, RNA-binding domain superfamilyHomologous Superfamily
J [auth R]IPR023029Small ribosomal subunit protein uS15, archaea/eukaryotesFamily
J [auth R]IPR000589Small ribosomal subunit protein uS15Family
K [auth S]IPR023407Small ribosomal subunit protein eS27, zinc-binding domain superfamilyHomologous Superfamily
K [auth S]IPR000592Small ribosomal subunit protein eS27Family
K [auth S]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
L [auth T]IPR038551Ribosomal protein eS26 superfamilyHomologous Superfamily
L [auth T]IPR000892Small ribosomal subunit protein eS26Family
M [auth U]IPR028626Ribosomal protein eS28 conserved siteConserved Site
M [auth U]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
M [auth U]IPR000289Small ribosomal subunit protein eS28Family
N [auth V]IPR001971Small ribosomal subunit protein uS11Family
N [auth V]IPR036967Small ribosomal subunit protein uS11 superfamilyHomologous Superfamily
N [auth V]IPR018102Small ribosomal subunit protein uS11, conserved siteConserved Site
O [auth W]IPR001593Small ribosomal subunit protein eS1Family
O [auth W]IPR027500Small ribosomal subunit protein eS1, eukaryotesFamily
P [auth X]IPR019979Small ribosomal subunit protein uS17, conserved siteConserved Site
P [auth X]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
P [auth X]IPR000266Small ribosomal subunit protein uS17Family
P [auth X]IPR032440Small ribosomal subunit protein uS17, N-terminalDomain
Q [auth Y]IPR001976Small ribosomal subunit protein eS24Family
Q [auth Y]IPR012678Ribosomal protein uL23/eL15/eS24 core domain superfamilyHomologous Superfamily
Q [auth Y]IPR018098Small ribosomal subunit protein eS24 conserved siteConserved Site
R [auth Z]IPR001047Small ribosomal subunit protein eS8Family
R [auth Z]IPR022309Ribosomal protein eS8/ribosomal biogenesis NSA2Family
R [auth Z]IPR018283Small ribosomal subunit protein eS8, conserved siteConserved Site
S [auth b]IPR018079Small ribosomal subunit protein uS4, conserved siteConserved Site
S [auth b]IPR002942RNA-binding S4 domainDomain
S [auth b]IPR001912Small ribosomal subunit protein uS4, N-terminalDomain
S [auth b]IPR005710Small ribosomal subunit protein uS4, eukaryotic/archaealFamily
S [auth b]IPR036986RNA-binding S4 domain superfamilyHomologous Superfamily
S [auth b]IPR022801Small ribosomal subunit protein uS4Family
B [auth q]IPR001209Small ribosomal subunit protein uS14Family
B [auth q]IPR039744Small ribosomal subunit protein uS14, eukaryotes/archaeaFamily
B [auth q]IPR043140Small ribosomal subunit protein uS14 superfamilyHomologous Superfamily
T [auth f]IPR005707Small ribosomal subunit protein uS2, eukaryotic/archaealFamily
T [auth f]IPR023591Small ribosomal subunit protein uS2, flavodoxin-like domain superfamilyHomologous Superfamily
T [auth f]IPR018130Small ribosomal subunit protein uS2, conserved siteConserved Site
T [auth f]IPR001865Small ribosomal subunit protein uS2Family
T [auth f]IPR027498Small ribosomal subunit protein uS2, eukaryoticFamily
U [auth d]IPR000851Small ribosomal subunit protein uS5Family
U [auth d]IPR005711Small ribosomal subunit protein uS5, eukaryotic/archaealFamily
U [auth d]IPR005324Small ribosomal subunit protein uS5, C-terminalDomain
U [auth d]IPR013810Small ribosomal subunit protein uS5, N-terminalDomain
U [auth d]IPR020568Ribosomal protein uS5 domain 2-type superfamilyHomologous Superfamily
U [auth d]IPR018192Small ribosomal subunit protein uS5, N-terminal, conserved siteConserved Site
U [auth d]IPR014721Small ribosomal subunit protein uS5 domain 2-type fold, subgroupHomologous Superfamily
V [auth e]IPR000630Small ribosomal subunit protein uS8Family
V [auth e]IPR047863Small ribosomal subunit protein uS8, conserved siteConserved Site
V [auth e]IPR035987Small ribosomal subunit protein uS8 superfamilyHomologous Superfamily
W [auth g]IPR038579Small ribosomal subunit protein eS21 superfamilyHomologous Superfamily
W [auth g]IPR001931Small ribosomal subunit protein eS21Family
X [auth a]IPR004977Small ribosomal subunit protein eS25Family
Y [auth i]IPR000530Small ribosomal subunit protein eS12Family
Y [auth i]IPR004038Ribosomal protein eL8/eL30/eS12/Gadd45Domain
Y [auth i]IPR029064Ribosomal protein eL30-like superfamilyHomologous Superfamily
Y [auth i]IPR047860Small ribosomal subunit protein eS12, conserved siteConserved Site
Z [auth j]IPR002906Small ribosomal subunit protein eS31Domain
Z [auth j]IPR029071Ubiquitin-like domain superfamilyHomologous Superfamily
Z [auth j]IPR011332Zinc-binding ribosomal proteinHomologous Superfamily
Z [auth j]IPR000626Ubiquitin-like domainDomain
Z [auth j]IPR038582Small ribosomal subunit protein eS31 eukaryotic-type superfamilyHomologous Superfamily
AA [auth P]IPR014401Small ribosomal subunit protein eS6-likeFamily
AA [auth P]IPR001377Small ribosomal subunit protein eS6Family
BA [auth k]IPR036401Small ribosomal subunit protein eS17 superfamilyHomologous Superfamily
BA [auth k]IPR001210Small ribosomal subunit protein eS17Family
C [auth r]IPR020568Ribosomal protein uS5 domain 2-type superfamilyHomologous Superfamily
C [auth r]IPR000754Small ribosomal subunit protein uS9Family
C [auth r]IPR014721Small ribosomal subunit protein uS5 domain 2-type fold, subgroupHomologous Superfamily
DA [auth m]IPR004044K Homology domain, type 2Domain
DA [auth m]IPR015946K homology domain-like, alpha/betaHomologous Superfamily
DA [auth m]IPR036419Ribosomal protein S3, C-terminal domain superfamilyHomologous Superfamily
DA [auth m]IPR001351Small ribosomal subunit protein uS3, C-terminalDomain
DA [auth m]IPR005703Small ribosomal subunit protein uS3, eukaryotic/archaealFamily
DA [auth m]IPR009019K homology domain superfamily, prokaryotic typeHomologous Superfamily
EA [auth n]IPR037447Small ribosomal subunit protein eS10Family
EA [auth n]IPR036388Winged helix-like DNA-binding domain superfamilyHomologous Superfamily
EA [auth n]IPR005326Plectin/eS10, N-terminalDomain
FA [auth o]IPR001266Small ribosomal subunit protein eS19Family
FA [auth o]IPR036388Winged helix-like DNA-binding domain superfamilyHomologous Superfamily
FA [auth o]IPR036390Winged helix DNA-binding domain superfamilyHomologous Superfamily
GA [auth c]IPR006846Small ribosomal subunit protein eS30Family
HA [auth h]IPR012677Nucleotide-binding alpha-beta plait domain superfamilyHomologous Superfamily
HA [auth h]IPR000504RNA recognition motif domainDomain
HA [auth h]IPR035979RNA-binding domain superfamilyHomologous Superfamily
D [auth t]IPR002222Small ribosomal subunit protein uS19Family
D [auth t]IPR023575Small ribosomal subunit protein uS19, superfamilyHomologous Superfamily
D [auth t]IPR020934Small ribosomal subunit protein uS19, conserved siteConserved Site
D [auth t]IPR005713Small ribosomal subunit protein uS19, eukaryotic/archaealFamily
E [auth u]IPR027437Small ribosomal subunit protein uS13, C-terminalHomologous Superfamily
E [auth u]IPR001892Small ribosomal subunit protein uS13Family
E [auth u]IPR018269Small ribosomal subunit protein uS13, conserved siteConserved Site
E [auth u]IPR010979Small ribosomal subunit protein uS13-like, H2THHomologous Superfamily
F [auth L]IPR013843Small ribosomal subunit protein eS4, N-terminalDomain
F [auth L]IPR032277Small ribosomal subunit protein eS4, C-terminal domainDomain
F [auth L]IPR002942RNA-binding S4 domainDomain
F [auth L]IPR013845Small ribosomal subunit protein eS4, central regionDomain
F [auth L]IPR000876Small ribosomal subunit protein eS4Family
F [auth L]IPR014722Large ribosomal subunit protein uL2, domain 2Homologous Superfamily
F [auth L]IPR038237Small ribosomal subunit protein eS4, central domain superfamilyHomologous Superfamily
F [auth L]IPR041982Small ribosomal subunit protein eS4, KOW domainDomain
F [auth L]IPR036986RNA-binding S4 domain superfamilyHomologous Superfamily
F [auth L]IPR005824KOWDomain
G [auth M]IPR006032Small ribosomal subunit protein uS12Family
G [auth M]IPR012340Nucleic acid-binding, OB-foldHomologous Superfamily
G [auth M]IPR005680Small ribosomal subunit protein uS12, eukaryotic/archaealFamily
H [auth O]IPR020606Small ribosomal subunit protein uS7, conserved siteConserved Site
H [auth O]IPR000235Small ribosomal subunit protein uS7Family
H [auth O]IPR036823Small ribosomal subunit protein uS7 domain superfamilyHomologous Superfamily
H [auth O]IPR023798Small ribosomal subunit protein uS7 domainDomain
H [auth O]IPR005716Ribosomal protein uS7, eukaryotic/archaealFamily
I [auth Q]IPR000554Small ribosomal subunit protein eS7Family