Annotations: 5OID

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	JAB1/MPN domain-like	8053299	3001105	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	JAB1/MPN domain-like	8053300	3001105	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF15253	e5oidA2	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: PF15253	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF15253	SCL-interrupting locus protein N-terminus (STIL_N)	SCL-interrupting locus protein N-terminus	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Putative uncharacterized protein	-	microtubule organizing center organization microtubule cytoskeleton organization cellular component organization centrosome duplication organelle organization centrosome cycle cellular process microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process mitotic cell cycle mitotic spindle organization microtubule organizing center organization microtubule cytoskeleton organization cellular component organization centrosome duplication organelle organization centrosome cycle cellular process microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process mitotic cell cycle mitotic spindle organization mitotic cell cycle process microtubule cytoskeleton organization involved in mitosis spindle organization cellular response to stimulus regulation of biological process regulation of cellular process cell surface receptor signaling pathway response to stimulus signaling biological regulation smoothened signaling pathway cell communication signal transduction protein localization to microtubule cytoskeleton protein localization cellular localization protein localization to microtubule organizing center localization protein localization to cytoskeleton protein localization to organelle cellular macromolecule localization macromolecule localization protein localization to centrosome	intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle centriole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle centrosome
B	Centrosomal protein of 85 kDa	identical protein binding protein binding binding	regulation of cellular process regulation of catalytic activity negative regulation of biological process negative regulation of catalytic activity regulation of transferase activity negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of kinase activity negative regulation of transferase activity regulation of phosphate metabolic process phosphate-containing compound metabolic process negative regulation of protein modification process phosphorus metabolic process protein modification process regulation of cellular process regulation of catalytic activity negative regulation of biological process negative regulation of catalytic activity regulation of transferase activity negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of kinase activity negative regulation of transferase activity regulation of phosphate metabolic process phosphate-containing compound metabolic process negative regulation of protein modification process phosphorus metabolic process protein modification process negative regulation of protein metabolic process regulation of biological process protein phosphorylation phosphorylation cellular metabolic process regulation of protein metabolic process negative regulation of metabolic process regulation of cellular metabolic process primary metabolic process regulation of molecular function regulation of kinase activity negative regulation of protein phosphorylation macromolecule modification regulation of phosphorus metabolic process metabolic process macromolecule metabolic process regulation of metabolic process regulation of protein modification process regulation of protein phosphorylation negative regulation of phosphate metabolic process organic substance metabolic process negative regulation of cellular process protein metabolic process negative regulation of macromolecule metabolic process organonitrogen compound metabolic process biological regulation negative regulation of molecular function negative regulation of protein kinase activity regulation of protein kinase activity regulation of macromolecule metabolic process negative regulation of phosphorus metabolic process regulation of phosphorylation cellular process negative regulation of phosphorylation centriole assembly microtubule organizing center organization organelle assembly non-membrane-bounded organelle assembly microtubule cytoskeleton organization cellular component organization cellular component biogenesis organelle organization cellular component assembly microtubule-based process cellular component organization or biogenesis cytoskeleton organization cell cycle chromosome segregation cell cycle process centrosome separation mitotic cell cycle mitotic centrosome separation centrosome cycle regulation of cell cycle mitotic nuclear division regulation of cell cycle process organelle fission regulation of mitotic centrosome separation nuclear division mitotic cell cycle process cell migration cell motility centrosome duplication centriole replication	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle cytoskeleton spindle spindle pole microtubule cytoskeleton cell periphery cell cortex cytoplasm Golgi apparatus endomembrane system centrosome microtubule organizing center pericentriolar material centriole cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR026123	SCL-interrupting locus protein	Family
B	IPR040210	Cep85/Cep85L	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
B	Pharos: Q6P2H3	large cell medulloblastoma osteosarcoma lung cancer malignant mesothelioma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.