Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
E [auth D]SCOP2B SuperfamilySNARE-like8082715 3001113 SCOP2B (2022-06-29)
O [auth I]SCOP2B SuperfamilySNARE-like8082715 3001113 SCOP2B (2022-06-29)
H [auth R]SCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
L [auth M]SCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
P [auth J]SCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyRas-like P-loop GTPases8089854 3002022 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF00400e5nztA1 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF00400ECOD (1.6)
APF04053e5nztA2 A: beta duplicates or obligate multimersX: beta-propeller-likeH: beta-propellerT: 7-bladedF: PF04053ECOD (1.6)
APF04053e5nztA3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF04053ECOD (1.6)
APF06957e5nztA4 A: alpha superhelicesX: Repetitive alpha hairpinsH: Coatomer subunit alpha C-terminal domain (From Topology)T: Coatomer subunit alpha C-terminal domainF: PF06957ECOD (1.6)
APF06957e5nztA5 A: few secondary structure elementsX: RING/U-box-likeH: RING/U-box-likeT: RING/U-boxF: PF06957ECOD (1.6)
B [auth E]PF04733e5nztE1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF04733ECOD (1.6)
C [auth B]PF07718e5nztB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07718ECOD (1.6)
C [auth B]PF01602e5nztB3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
C [auth B]PF14806e5nztB2 A: a+b two layersX: TBP-likeH: Subdomain of clathrin and coatomer appendage domain (From Topology)T: Subdomain of clathrin and coatomer appendage domainF: PF14806ECOD (1.6)
M [auth N]PF01602e5nztN1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
H [auth R]PF00025e5nztR1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
L [auth M]PF00025e5nztM1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
P [auth J]PF00025e5nztJ1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
FPF00025e5nztF1 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: PF00025ECOD (1.6)
GPF08752e5nztG2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF08752ECOD (1.6)
GPF01602e5nztG3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
GPF16381e5nztG1 A: a+b two layersX: TBP-likeH: Subdomain of clathrin and coatomer appendage domain (From Topology)T: Subdomain of clathrin and coatomer appendage domainF: PF16381ECOD (1.6)
J [auth K]PF08752e5nztK2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF08752ECOD (1.6)
J [auth K]PF01602e5nztK1 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: PF01602ECOD (1.6)
J [auth K]PF16381e5nztK3 A: a+b two layersX: TBP-likeH: Subdomain of clathrin and coatomer appendage domain (From Topology)T: Subdomain of clathrin and coatomer appendage domainF: PF16381ECOD (1.6)
I [auth Z]PF01217e5nztZ1 A: a+b three layersX: Profilin-likeH: profilin-like (From Topology)T: profilin-likeF: PF01217ECOD (1.6)
K [auth L]PF01217e5nztL1 A: a+b three layersX: Profilin-likeH: profilin-like (From Topology)T: profilin-likeF: PF01217ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF04053Coatomer WD associated region (Coatomer_WDAD)Coatomer WD associated region- Repeat
PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
B [auth E]PF04733Coatomer epsilon subunit (Coatomer_E)Coatomer epsilon subunit- Repeat
C [auth B],
M [auth N]
PF01602Adaptin N terminal region (Adaptin_N)Adaptin N terminal region- Repeat
C [auth B],
M [auth N]
PF14806Coatomer beta subunit appendage platform (Coatomer_b_Cpla)Coatomer beta subunit appendage platformThis family is found at the C-terminus of the coatamer beta subunit proteins (Beta-coat proteins). It is a platform domain on the appendage that carries a highly conserved tryptophan.Domain
D [auth C],
N [auth H]
PF04053Coatomer WD associated region (Coatomer_WDAD)Coatomer WD associated region- Repeat
D [auth C],
N [auth H]
PF00400WD domain, G-beta repeat (WD40)WD domain, G-beta repeat- Repeat
E [auth D],
O [auth I]
PF01217Clathrin adaptor complex small chain (Clat_adaptor_s)Clathrin adaptor complex small chain- Domain
F,
H [auth R],
L [auth M],
P [auth J]
PF00025ADP-ribosylation factor family (Arf)ADP-ribosylation factor familyPfam combines a number of different Prosite families togetherDomain
G,
J [auth K]
PF16381Coatomer subunit gamma-1 C-terminal appendage platform (Coatomer_g_Cpla)Coatomer subunit gamma-1 C-terminal appendage platformCoatomer_g_Cpla is the very C-terminal domain of the eukaryotic Coatomer subunit gamma-1 proteins. It acts as a platform domain to the C-terminal appendage. It carries one single protein/protein interaction site, which is the binding site for ARFGAP2 ...Coatomer_g_Cpla is the very C-terminal domain of the eukaryotic Coatomer subunit gamma-1 proteins. It acts as a platform domain to the C-terminal appendage. It carries one single protein/protein interaction site, which is the binding site for ARFGAP2 or ADP-ribosylation factor GTPase-activating protein. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The gamma-COPI is part of one of two subcomplexes that make up the heptameric coatomer complex along with the beta, delta and zeta subunits [1].
Domain
G,
J [auth K]
PF01602Adaptin N terminal region (Adaptin_N)Adaptin N terminal region- Repeat
G,
J [auth K]
PF08752Coatomer gamma subunit appendage platform subdomain (COP-gamma_platf)Coatomer gamma subunit appendage platform subdomainCOPI-coated vesicles function in retrograde transport from the Golgi to the ER, and in intra-Golgi transport. This is the platform subdomain of the coatomer gamma subunit appendage domain. It carries a protein-protein interaction site at U ...COPI-coated vesicles function in retrograde transport from the Golgi to the ER, and in intra-Golgi transport. This is the platform subdomain of the coatomer gamma subunit appendage domain. It carries a protein-protein interaction site at UniProt:P53620, residue W776, which in yeast binds to the ARFGAP Glo3p, and in mammalian gamma-COP binds to a Glo3p orthologue, ARFGAP2 [1].
Domain
I [auth Z],
K [auth L]
PF01217Clathrin adaptor complex small chain (Clat_adaptor_s)Clathrin adaptor complex small chain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Coatomer subunit alpha
B [auth E]Coatomer subunit epsilon
C [auth B],
M [auth N]
Coatomer subunit beta
D [auth C],
N [auth H]
Coatomer subunit beta'
E [auth D],
O [auth I]
Coatomer subunit delta-
F,
H [auth R],
L [auth M],
P [auth J]
ADP-ribosylation factor 1
G,
J [auth K]
Coatomer subunit gamma-1
I [auth Z],
K [auth L]
Coatomer subunit zeta-1-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR019775WD40 repeat, conserved siteConserved Site
IPR016391Coatomer subunit alphaFamily
IPR010714Coatomer, alpha subunit, C-terminalDomain
IPR047312Coatomer subunit alpha, WD Associated RegionDomain
IPR011048Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamilyHomologous Superfamily
IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
IPR006692Coatomer, WD associated regionDomain
IPR001680WD40 repeatRepeat
IPR020472G-protein beta WD-40 repeatRepeat
B [auth E]IPR006822Coatomer, epsilon subunitFamily
B [auth E]IPR011990Tetratricopeptide-like helical domain superfamilyHomologous Superfamily
C [auth B],
M [auth N]
IPR016460Coatomer beta subunit (COPB1)Family
C [auth B],
M [auth N]
IPR016024Armadillo-type foldHomologous Superfamily
C [auth B],
M [auth N]
IPR002553Clathrin/coatomer adaptor, adaptin-like, N-terminalDomain
C [auth B],
M [auth N]
IPR011710Coatomer beta subunit, C-terminalDomain
C [auth B],
M [auth N]
IPR029446Coatomer beta subunit, appendage platform domainDomain
C [auth B],
M [auth N]
IPR011989Armadillo-like helicalHomologous Superfamily
D [auth C],
N [auth H]
IPR036322WD40-repeat-containing domain superfamilyHomologous Superfamily
D [auth C],
N [auth H]
IPR016453Coatomer beta' subunit (COPB2)Family
D [auth C],
N [auth H]
IPR006692Coatomer, WD associated regionDomain
D [auth C],
N [auth H]
IPR001680WD40 repeatRepeat
D [auth C],
N [auth H]
IPR020472G-protein beta WD-40 repeatRepeat
D [auth C],
N [auth H]
IPR015943WD40/YVTN repeat-like-containing domain superfamilyHomologous Superfamily
E [auth D],
O [auth I]
IPR011012Longin-like domain superfamilyHomologous Superfamily
E [auth D],
O [auth I]
IPR027059Coatomer delta subunitFamily
E [auth D],
O [auth I]
IPR022775AP complex, mu/sigma subunitDomain
E [auth D],
O [auth I]
IPR036168AP-2 complex subunit mu, C-terminal superfamilyHomologous Superfamily
E [auth D],
O [auth I]
IPR028565Mu homology domainDomain
F,
H [auth R],
L [auth M],
P [auth J]
IPR045872ADP-ribosylation factor 1-5Family
F,
H [auth R],
L [auth M],
P [auth J]
IPR005225Small GTP-binding protein domainDomain
F,
H [auth R],
L [auth M],
P [auth J]
IPR006689Small GTPase superfamily, ARF/SAR typeFamily
F,
H [auth R],
L [auth M],
P [auth J]
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
G,
J [auth K]
IPR016024Armadillo-type foldHomologous Superfamily
G,
J [auth K]
IPR002553Clathrin/coatomer adaptor, adaptin-like, N-terminalDomain
G,
J [auth K]
IPR013040Coatomer, gamma subunit, appendage, Ig-like subdomainDomain
G,
J [auth K]
IPR013041Clathrin adaptor, appendage, Ig-like subdomain superfamilyHomologous Superfamily
G,
J [auth K]
IPR011989Armadillo-like helicalHomologous Superfamily
G,
J [auth K]
IPR032154Coatomer subunit gamma, C-terminalDomain
G,
J [auth K]
IPR017106Coatomer gamma subunitFamily
G,
J [auth K]
IPR037067Coatomer, gamma subunit, appendage domain superfamilyHomologous Superfamily
G,
J [auth K]
IPR012295TBP domain superfamilyHomologous Superfamily
G,
J [auth K]
IPR009028Coatomer/calthrin adaptor appendage, C-terminal subdomainHomologous Superfamily
I [auth Z],
K [auth L]
IPR000804Clathrin adaptor complex, small chainConserved Site
I [auth Z],
K [auth L]
IPR022775AP complex, mu/sigma subunitDomain
I [auth Z],
K [auth L]
IPR039652Coatomer subunit zetaFamily
I [auth Z],
K [auth L]
IPR011012Longin-like domain superfamilyHomologous Superfamily