5NGO

Crystal structure of the PARP domain of Arabidopsis RADICAL-INDUCED CELL DEATH1

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00644	e5ngoA1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
B	PF00644	e5ngoB1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
C [auth E]	PF00644	e5ngoE1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
D [auth G]	PF00644	e5ngoG1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
E [auth D]	PF00644	e5ngoD1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
F	PF00644	e5ngoF1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
G [auth H]	PF00644	e5ngoH1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)
H [auth C]	PF00644	e5ngoC1	A: a+b complex topology	X: ADP-ribosylation (From Topology)	H: ADP-ribosylation (From Topology)	T: ADP-ribosylation	F: PF00644	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth E], D [auth G], E [auth D], A, B, C [auth E], D [auth G], E [auth D], F, G [auth H], H [auth C]	PF00644	Poly(ADP-ribose) polymerase catalytic domain (PARP)	Poly(ADP-ribose) polymerase catalytic domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth E], D [auth G], E [auth D], A, B, C [auth E], D [auth G], E [auth D], F, G [auth H], H [auth C]	Inactive poly [ADP-ribose] polymerase RCD1	NAD+ ADP-ribosyltransferase activity pentosyltransferase activity glycosyltransferase activity transferase activity catalytic activity	response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation response to inorganic substance developmental process multicellular organismal process reproductive system development reproductive process embryo development response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation response to inorganic substance developmental process multicellular organismal process reproductive system development reproductive process embryo development developmental process involved in reproduction multicellular organism development fruit development embryo development ending in seed dormancy seed development anatomical structure development reproductive structure development post-embryonic development system development cellular response to stimulus response to organic substance regulation of cellular process signaling hormone-mediated signaling pathway intracellular signal transduction cell communication cellular response to endogenous stimulus ethylene-activated signaling pathway response to hormone response to ethylene signal transduction cellular response to organic substance cellular response to hormone stimulus regulation of biological process phosphorelay signal transduction system cellular response to ethylene stimulus response to endogenous stimulus biological regulation cellular response to chemical stimulus cellular process response to lipid cellular response to jasmonic acid stimulus response to jasmonic acid response to fatty acid jasmonic acid mediated signaling pathway cellular response to oxygen-containing compound cellular response to fatty acid cellular response to lipid plant organ development root morphogenesis post-embryonic root morphogenesis post-embryonic plant organ morphogenesis post-embryonic plant morphogenesis plant organ morphogenesis post-embryonic root development anatomical structure morphogenesis lateral root morphogenesis lateral root development post-embryonic plant organ development root development root system development response to oxidative stress response to ozone response to reactive oxygen species cell death programmed cell death cellular metabolic process reactive oxygen species metabolic process metabolic process regulation of cellular metabolic process regulation of metabolic process regulation of reactive oxygen species metabolic process response to superoxide response to oxygen radical biological process involved in interspecies interaction between organisms response to other organism defense response response to external stimulus response to biotic stimulus defense response to bacterium defense response to other organism response to bacterium response to external biotic stimulus response to osmotic stress response to salt stress nitric oxide metabolic process nitric oxide biosynthetic process biosynthetic process reactive nitrogen species metabolic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle lumen intracellular organelle organelle lumen organelle nuclear periphery nuclear lumen nuclear matrix cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth E], D [auth G], E [auth D], A, B, C [auth E], D [auth G], E [auth D], F, G [auth H], H [auth C]	IPR022003	RST domain	Domain
A, B, C [auth E], D [auth G], E [auth D], A, B, C [auth E], D [auth G], E [auth D], F, G [auth H], H [auth C]	IPR004170	WWE domain	Domain
A, B, C [auth E], D [auth G], E [auth D], A, B, C [auth E], D [auth G], E [auth D], F, G [auth H], H [auth C]	IPR012317	Poly(ADP-ribose) polymerase, catalytic domain	Domain
A, B, C [auth E], D [auth G], E [auth D], A, B, C [auth E], D [auth G], E [auth D], F, G [auth H], H [auth C]	IPR044964	Inactive poly [ADP-ribose] polymerase RCD1/SRO1-5	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.