Annotations: 5NCN

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Mob1/phocein	8086795	4000646	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Mob1/phocein	8086796	3000866	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03637	e5ncnA1	A: alpha bundles	X: Bromodomain-like	H: Mob1/phocein (From Topology)	T: Mob1/phocein	F: PF03637	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.140.30	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03637	Mob1/phocein family (Mob1_phocein)	Mob1/phocein family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	DBF2 kinase activator protein MOB1	enzyme regulator activity molecular function regulator activity kinase regulator activity kinase activator activity enzyme activator activity molecular function activator activity protein kinase activator activity protein kinase regulator activity cation binding ion binding binding metal ion binding small molecule binding	regulation of cytokinesis regulation of biological process regulation of cellular process regulation of cell cycle process biological regulation cytokinesis regulation of cell division cellular process cell division cell cycle regulation of cell cycle cell cycle process mitotic cell cycle process cytoskeleton-dependent cytokinesis regulation of cytokinesis regulation of biological process regulation of cellular process regulation of cell cycle process biological regulation cytokinesis regulation of cell division cellular process cell division cell cycle regulation of cell cycle cell cycle process mitotic cell cycle process cytoskeleton-dependent cytokinesis mitotic cytokinesis mitotic cell cycle regulation of cell cycle phase transition cell cycle phase transition exit from mitosis cellular component organization regulation of mitotic cell cycle cellular component organization or biogenesis mitotic nuclear division organelle fission regulation of mitotic cell cycle phase transition nuclear division organelle organization regulation of exit from mitosis mitotic cell cycle phase transition positive regulation of phosphorylation regulation of protein modification process regulation of protein phosphorylation positive regulation of protein metabolic process positive regulation of biological process positive regulation of cellular metabolic process positive regulation of phosphate metabolic process regulation of primary metabolic process positive regulation of metabolic process positive regulation of protein modification process organic substance metabolic process regulation of phosphate metabolic process phosphate-containing compound metabolic process positive regulation of macromolecule metabolic process protein metabolic process positive regulation of protein phosphorylation phosphorus metabolic process protein modification process positive regulation of cellular process organonitrogen compound metabolic process protein phosphorylation positive regulation of phosphorus metabolic process phosphorylation cellular metabolic process regulation of protein metabolic process regulation of cellular metabolic process primary metabolic process regulation of macromolecule metabolic process macromolecule modification regulation of phosphorus metabolic process metabolic process regulation of phosphorylation macromolecule metabolic process regulation of metabolic process cellular response to stimulus response to stimulus signaling signal transduction cell communication	protein kinase complex transferase complex, transferring phosphorus-containing groups protein-containing complex catalytic complex serine/threonine protein kinase complex transferase complex intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle spindle pole body cellular anatomical entity protein kinase complex transferase complex, transferring phosphorus-containing groups protein-containing complex catalytic complex serine/threonine protein kinase complex transferase complex intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle spindle pole body cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle chromosome, centromeric region chromosome chromosomal region membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen organelle lumen nuclear periphery nuclear lumen cellular bud neck cellular bud site of polarized growth cytoplasm mitotic spindle pole body Sid2-Mob1 complex
B	Cell cycle protein kinase DBF2	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding catalytic activity, acting on a protein kinase activity protein kinase activity transferase activity catalytic activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups protein serine/threonine kinase activity RNA binding nucleic acid binding protein serine kinase activity	regulation of cytokinesis regulation of biological process regulation of cellular process regulation of cell cycle process biological regulation cytokinesis regulation of cell division cellular process cell division cell cycle regulation of cell cycle cell cycle process cellular component organization nuclear division regulation of cytokinesis regulation of biological process regulation of cellular process regulation of cell cycle process biological regulation cytokinesis regulation of cell division cellular process cell division cell cycle regulation of cell cycle cell cycle process cellular component organization nuclear division organelle organization organelle fission cellular component organization or biogenesis protein localization regulation of localization cellular localization regulation of protein localization protein localization to cell division site regulation of protein localization to cell division site localization regulation of cellular localization cellular macromolecule localization macromolecule localization phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process phosphorus metabolic process cellular response to stimulus response to stimulus signaling signal transduction intracellular signal transduction cell communication mitotic nuclear division cell cycle phase transition exit from mitosis mitotic cell cycle mitotic cell cycle process mitotic cell cycle phase transition homeostatic process intracellular pH reduction regulation of intracellular pH vacuolar acidification cellular homeostasis chemical homeostasis intracellular monoatomic cation homeostasis regulation of pH monoatomic ion homeostasis intracellular chemical homeostasis regulation of biological quality monoatomic cation homeostasis regulation of cellular pH intracellular monoatomic ion homeostasis	intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle spindle pole body cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cellular bud neck cellular bud site of polarized growth membrane-bounded organelle intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle spindle pole body cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cellular bud neck cellular bud site of polarized growth membrane-bounded organelle nucleus intracellular membrane-bounded organelle protein-containing complex Sid2-Mob1 complex cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036703	MOB kinase activator superfamily	Homologous Superfamily
A	IPR005301	MOB kinase activator family	Family
B	IPR017441	Protein kinase, ATP binding site	Binding Site
B	IPR011009	Protein kinase-like domain superfamily	Homologous Superfamily
B	IPR000719	Protein kinase domain	Domain
B	IPR000961	AGC-kinase, C-terminal	Domain
B	IPR017892	Protein kinase, C-terminal	Domain
B	IPR008271	Serine/threonine-protein kinase, active site	Active Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.