5N8N

Contracted sheath of a Pseudomonas aeruginosa type six secretion system consisting of TssB1 and TssC1

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05591	e5n8nA1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
AA [auth a]	PF05591	e5n8na1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
C	PF05591	e5n8nC1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
CA [auth c]	PF05591	e5n8nc1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
E	PF05591	e5n8nE1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
I	PF05591	e5n8nI1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
K	PF05591	e5n8nK1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
M	PF05591	e5n8nM1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
O	PF05591	e5n8nO1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
Q	PF05591	e5n8nQ1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
S	PF05591	e5n8nS1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
U	PF05591	e5n8nU1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
W	PF05591	e5n8nW1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
G	PF05591	e5n8nG1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
Y	PF05591	e5n8nY1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
BA [auth b]	PF18945	e5n8nb2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
BA [auth b]	PF05943	e5n8nb1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
D	PF18945	e5n8nD2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
D	PF05943	e5n8nD1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
DA [auth d]	PF18945	e5n8nd1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
DA [auth d]	PF05943	e5n8nd2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
H	PF18945	e5n8nH2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
H	PF05943	e5n8nH1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
J	PF18945	e5n8nJ2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
J	PF05943	e5n8nJ1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
L	PF18945	e5n8nL1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
L	PF05943	e5n8nL2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
P	PF18945	e5n8nP1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
P	PF05943	e5n8nP2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
R	PF18945	e5n8nR1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
R	PF05943	e5n8nR2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
T	PF18945	e5n8nT1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
T	PF05943	e5n8nT2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
V	PF18945	e5n8nV1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
V	PF05943	e5n8nV2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
Z	PF18945	e5n8nZ2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
Z	PF05943	e5n8nZ1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
B	PF18945	e5n8nB2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
B	PF05943	e5n8nB1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
F	PF18945	e5n8nF1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
F	PF05943	e5n8nF2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
N	PF18945	e5n8nN2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
N	PF05943	e5n8nN1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
X	PF18945	e5n8nX1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
X	PF05943	e5n8nX2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, AA [auth a], C, CA [auth c], E, A, AA [auth a], C, CA [auth c], E, G, I, K, M, O, Q, S, U, W, Y	PF05591	Type VI secretion system, VipA, VC_A0107 or Hcp2 (T6SS_VipA)	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	Family
B, BA [auth b], D, DA [auth d], F, B, BA [auth b], D, DA [auth d], F, H, J, L, N, P, R, T, V, X, Z	PF05943	EvpB/VC_A0108, tail sheath N-terminal domain (VipB)	EvpB/VC_A0108, tail sheath N-terminal domain	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB ...	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell [1].	Domain
B, BA [auth b], D, DA [auth d], F, B, BA [auth b], D, DA [auth d], F, H, J, L, N, P, R, T, V, X, Z	PF18945	EvpB/VC_A0108, tail sheath gpW/gp25-like domain (VipB_2)	EvpB/VC_A0108, tail sheath gpW/gp25-like domain	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/Vip ...	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell [1]. This entry represents the gpW/gp25-like domain.	Domain

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, AA [auth a], C, CA [auth c], E, A, AA [auth a], C, CA [auth c], E, G, I, K, M, O, Q, S, U, W, Y	IPR008312	Type VI secretion system sheath protein TssB1	Family
B, BA [auth b], D, DA [auth d], F, B, BA [auth b], D, DA [auth d], F, H, J, L, N, P, R, T, V, X, Z	IPR010269	Type VI secretion system TssC-like	Family
B, BA [auth b], D, DA [auth d], F, B, BA [auth b], D, DA [auth d], F, H, J, L, N, P, R, T, V, X, Z	IPR044032	TssC1, C-terminal	Domain
B, BA [auth b], D, DA [auth d], F, B, BA [auth b], D, DA [auth d], F, H, J, L, N, P, R, T, V, X, Z	IPR044031	TssC1, N-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.

Prepare Data

Validate Data

Deposit Data

Help and Resources

5N8N

Contracted sheath of a Pseudomonas aeruginosa type six secretion system consisting of TssB1 and TssC1

External Resource: Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Protein Family Annotation Pfam Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage