5N77

Crystal structure of the cytosolic domain of the CorA magnesium channel from Escherichia coli in complex with magnesium

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01544	e5n77A1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: PF01544	ECOD (1.6)
C	PF01544	e5n77C1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: PF01544	ECOD (1.6)
D	PF01544	e5n77D1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: PF01544	ECOD (1.6)
B	PF01544	e5n77B1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: PF01544	ECOD (1.6)
E	PF01544	e5n77E1	A: a+b three layers	X: CorA soluble domain-like (From Topology)	H: CorA soluble domain-like (From Topology)	T: CorA soluble domain-like	F: PF01544	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF01544	CorA-like Mg2+ transporter protein (CorA)	CorA-like Mg2+ transporter protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	Magnesium transport protein CorA	cobalt ion transmembrane transporter activity monoatomic cation transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transition metal ion transmembrane transporter activity metal ion transmembrane transporter activity transmembrane transporter activity nickel cation transmembrane transporter activity magnesium ion transmembrane transporter activity	localization transport magnesium ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport nickel cation transmembrane transport monoatomic ion transmembrane transport inorganic ion transmembrane transport inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport nickel cation transport localization transport magnesium ion transport monoatomic ion transport monoatomic cation transport establishment of localization metal ion transport nickel cation transmembrane transport monoatomic ion transmembrane transport inorganic ion transmembrane transport inorganic cation transmembrane transport transmembrane transport monoatomic cation transmembrane transport nickel cation transport transition metal ion transport cellular process cobalt ion transport	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR002523	Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB	Family
A, B, C, D, E	IPR004488	Magnesium/cobalt transport protein CorA	Family
A, B, C, D, E	IPR045861	CorA, cytoplasmic domain	Homologous Superfamily
A, B, C, D, E	IPR045863	CorA, transmembrane region	Homologous Superfamily

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C, D, E	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	CorA Superfamily Ion Transporters	CorA Mg²⁺ Transporter cytoplasmic domain with bound Mg²⁺

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.