5MYU

VipA-N2/VipB contracted sheath of type VI secretion system

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth a]	PF05591	e5myua1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
C [auth b]	PF05591	e5myub1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
E [auth c]	PF05591	e5myuc1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
G [auth d]	PF05591	e5myud1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
I [auth e]	PF05591	e5myue1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
K [auth f]	PF05591	e5myuf1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05591	ECOD (1.6)
B [auth A]	PF18945	e5myuA1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
B [auth A]	PF05943	e5myuA2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
D [auth B]	PF18945	e5myuB1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
D [auth B]	PF05943	e5myuB2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
F [auth C]	PF18945	e5myuC1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
F [auth C]	PF05943	e5myuC2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
H [auth D]	PF18945	e5myuD1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
H [auth D]	PF05943	e5myuD2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
J [auth E]	PF18945	e5myuE2	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
J [auth E]	PF05943	e5myuE1	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)
L [auth F]	PF18945	e5myuF1	A: a+b duplicates or obligate multimers	X: Creatinase/aminopeptidase-like	H: gpW/gp25-like (From Topology)	T: gpW/gp25-like	F: PF18945	ECOD (1.6)
L [auth F]	PF05943	e5myuF2	A: a/b three-layered sandwiches	X: Subtilisin-like	H: Domain III of tail sheath protein Gp18 (From Topology)	T: Domain III of tail sheath protein Gp18	F: PF05943	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth a], C [auth b], E [auth c], G [auth d], I [auth e], A [auth a], C [auth b], E [auth c], G [auth d], I [auth e], K [auth f]	PF05591	Type VI secretion system, VipA, VC_A0107 or Hcp2 (T6SS_VipA)	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	Family
B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], L [auth F]	PF05943	EvpB/VC_A0108, tail sheath N-terminal domain (VipB)	EvpB/VC_A0108, tail sheath N-terminal domain	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB ...	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell [1].	Domain
B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], L [auth F]	PF18945	EvpB/VC_A0108, tail sheath gpW/gp25-like domain (VipB_2)	EvpB/VC_A0108, tail sheath gpW/gp25-like domain	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/Vip ...	EvpB is a family of Gram-negative probable type VI secretion system components of the tail sheath. They have been known as COG:COG3517. These sheath-components, of which there are many copies in the sheath, are also variously referred to as VipA/VipB and TssB/TssC. On contact with another bacterial cell the sheath contracts and pushes the puncturing device and tube through the cell envelope and punches the target bacterial cell [1]. This entry represents the gpW/gp25-like domain.	Domain

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth a], C [auth b], E [auth c], G [auth d], I [auth e], A [auth a], C [auth b], E [auth c], G [auth d], I [auth e], K [auth f]	IPR008312	Type VI secretion system sheath protein TssB1	Family
B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], L [auth F]	IPR010269	Type VI secretion system TssC-like	Family
B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], L [auth F]	IPR044032	TssC1, C-terminal	Domain
B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], B [auth A], D [auth B], F [auth C], H [auth D], J [auth E], L [auth F]	IPR044031	TssC1, N-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.