5MVW

Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn)

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D [auth B]	Centrosomin	molecular adaptor activity	developmental process neuroblast proliferation multicellular organismal process cell population proliferation cellular developmental process neuroblast division nervous system development asymmetric cell division generation of neurons neurogenesis multicellular organism development asymmetric neuroblast division cell differentiation anatomical structure development developmental process neuroblast proliferation multicellular organismal process cell population proliferation cellular developmental process neuroblast division nervous system development asymmetric cell division generation of neurons neurogenesis multicellular organism development asymmetric neuroblast division cell differentiation anatomical structure development cellular process cell division neural precursor cell proliferation cell fate commitment system development embryonic cleavage embryo development digestive system development tube development midgut development digestive tract development central nervous system development photoreceptor cell differentiation cell development cell morphogenesis involved in neuron differentiation cell morphogenesis photoreceptor cell morphogenesis anatomical structure morphogenesis neuron differentiation neuron development photoreceptor cell development peripheral nervous system development microtubule organizing center organization microtubule cytoskeleton organization cellular component organization organelle organization centrosome cycle microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process mitotic cell cycle mitotic spindle organization mitotic cell cycle process microtubule cytoskeleton organization involved in mitosis spindle organization sexual reproduction reproductive process cellularization multicellular organismal reproductive process pole cell formation developmental process involved in reproduction gamete generation pole cell development anatomical structure formation involved in morphogenesis positive regulation of organelle organization regulation of cytoskeleton organization regulation of microtubule polymerization or depolymerization regulation of cellular process regulation of cellular component organization positive regulation of cellular component organization positive regulation of biological process cellular component biogenesis regulation of protein-containing complex assembly positive regulation of protein-containing complex assembly microtubule polymerization or depolymerization cellular component assembly positive regulation of protein polymerization protein-containing complex assembly positive regulation of cellular process protein polymerization regulation of biological process positive regulation of microtubule nucleation positive regulation of microtubule polymerization or depolymerization protein-containing complex organization positive regulation of cellular component biogenesis positive regulation of cytoskeleton organization biological regulation regulation of microtubule-based process microtubule polymerization regulation of cellular component biogenesis positive regulation of supramolecular fiber organization regulation of microtubule nucleation regulation of organelle organization microtubule nucleation regulation of microtubule polymerization regulation of protein polymerization positive regulation of microtubule polymerization regulation of supramolecular fiber organization supramolecular fiber organization regulation of microtubule cytoskeleton organization meiotic cell cycle regulation of cell cycle process centriole-centriole cohesion regulation of cell cycle regulation of centriole-centriole cohesion regulation of Golgi organization Golgi organization endomembrane system organization centriole assembly organelle assembly non-membrane-bounded organelle assembly centrosome duplication centriole replication	intracellular organelle intracellular anatomical structure cytoskeleton spindle organelle intracellular non-membrane-bounded organelle spindle pole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle membrane-bounded organelle Golgi apparatus cytoplasm intracellular membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoskeleton spindle organelle intracellular non-membrane-bounded organelle spindle pole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle membrane-bounded organelle Golgi apparatus cytoplasm intracellular membrane-bounded organelle endomembrane system centrosome microtubule organizing center pericentriolar material centriole cell projection cilium motile cilium plasma membrane bounded cell projection ciliary basal body
B [auth C], C [auth D]	Centrosomin	molecular adaptor activity	developmental process neuroblast proliferation multicellular organismal process cell population proliferation cellular developmental process neuroblast division nervous system development asymmetric cell division generation of neurons neurogenesis multicellular organism development asymmetric neuroblast division cell differentiation anatomical structure development developmental process neuroblast proliferation multicellular organismal process cell population proliferation cellular developmental process neuroblast division nervous system development asymmetric cell division generation of neurons neurogenesis multicellular organism development asymmetric neuroblast division cell differentiation anatomical structure development cellular process cell division neural precursor cell proliferation cell fate commitment system development embryonic cleavage embryo development digestive system development tube development midgut development digestive tract development central nervous system development photoreceptor cell differentiation cell development cell morphogenesis involved in neuron differentiation cell morphogenesis photoreceptor cell morphogenesis anatomical structure morphogenesis neuron differentiation neuron development photoreceptor cell development peripheral nervous system development microtubule organizing center organization microtubule cytoskeleton organization cellular component organization organelle organization centrosome cycle microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process mitotic cell cycle mitotic spindle organization mitotic cell cycle process microtubule cytoskeleton organization involved in mitosis spindle organization sexual reproduction reproductive process cellularization multicellular organismal reproductive process pole cell formation developmental process involved in reproduction gamete generation pole cell development anatomical structure formation involved in morphogenesis positive regulation of organelle organization regulation of cytoskeleton organization regulation of microtubule polymerization or depolymerization regulation of cellular process regulation of cellular component organization positive regulation of cellular component organization positive regulation of biological process cellular component biogenesis regulation of protein-containing complex assembly positive regulation of protein-containing complex assembly microtubule polymerization or depolymerization cellular component assembly positive regulation of protein polymerization protein-containing complex assembly positive regulation of cellular process protein polymerization regulation of biological process positive regulation of microtubule nucleation positive regulation of microtubule polymerization or depolymerization protein-containing complex organization positive regulation of cellular component biogenesis positive regulation of cytoskeleton organization biological regulation regulation of microtubule-based process microtubule polymerization regulation of cellular component biogenesis positive regulation of supramolecular fiber organization regulation of microtubule nucleation regulation of organelle organization microtubule nucleation regulation of microtubule polymerization regulation of protein polymerization positive regulation of microtubule polymerization regulation of supramolecular fiber organization supramolecular fiber organization regulation of microtubule cytoskeleton organization meiotic cell cycle regulation of cell cycle process centriole-centriole cohesion regulation of cell cycle regulation of centriole-centriole cohesion regulation of Golgi organization Golgi organization endomembrane system organization centriole assembly organelle assembly non-membrane-bounded organelle assembly centrosome duplication centriole replication	intracellular organelle intracellular anatomical structure cytoskeleton spindle organelle intracellular non-membrane-bounded organelle spindle pole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle membrane-bounded organelle Golgi apparatus cytoplasm intracellular membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoskeleton spindle organelle intracellular non-membrane-bounded organelle spindle pole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle membrane-bounded organelle Golgi apparatus cytoplasm intracellular membrane-bounded organelle endomembrane system centrosome microtubule organizing center pericentriolar material centriole cell projection cilium motile cilium plasma membrane bounded cell projection ciliary basal body

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D [auth B]	IPR012943	Centrosomin, N-terminal motif 1	Domain
B [auth C], C [auth D]	IPR012943	Centrosomin, N-terminal motif 1	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.