5MG5

A multi-component acyltransferase PhlABC from Pseudomonas protegens soaked with the monoacetylphloroglucinol (MAPG)

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	F_UNCLASSIFIED	e5mg5D2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
D	PF08541	e5mg5D1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
G	F_UNCLASSIFIED	e5mg5G2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
G	PF08541	e5mg5G1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
J	F_UNCLASSIFIED	e5mg5J2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
J	PF08541	e5mg5J1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
V	F_UNCLASSIFIED	e5mg5V2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
V	PF08541	e5mg5V1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
A	F_UNCLASSIFIED	e5mg5A2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF08541	e5mg5A1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
M	F_UNCLASSIFIED	e5mg5M1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
M	PF08541	e5mg5M2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
P	F_UNCLASSIFIED	e5mg5P1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
P	PF08541	e5mg5P2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
S	F_UNCLASSIFIED	e5mg5S2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: F_UNCLASSIFIED	ECOD (1.6)
S	PF08541	e5mg5S1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF08541	ECOD (1.6)
E	PF01796	e5mg5E1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
E	PF12172	e5mg5E2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
N	PF01796	e5mg5N1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
N	PF12172	e5mg5N2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
B	PF01796	e5mg5B1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
B	PF12172	e5mg5B2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
H	PF01796	e5mg5H1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
H	PF12172	e5mg5H2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
K	PF01796	e5mg5K1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
K	PF12172	e5mg5K2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
Q	PF01796	e5mg5Q1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
Q	PF12172	e5mg5Q2	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
T	PF01796	e5mg5T2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
T	PF12172	e5mg5T1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
W	PF01796	e5mg5W2	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: PF01796	ECOD (1.6)
W	PF12172	e5mg5W1	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: PF12172	ECOD (1.6)
U	PF00108	e5mg5U2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
U	PF22691	e5mg5U1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
C	PF00108	e5mg5C1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
C	PF22691	e5mg5C2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
F	PF00108	e5mg5F2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
F	PF22691	e5mg5F1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
I	PF00108	e5mg5I2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
I	PF22691	e5mg5I1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
L	PF00108	e5mg5L2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
L	PF22691	e5mg5L1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
O	PF00108	e5mg5O1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
O	PF22691	e5mg5O2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
R	PF00108	e5mg5R1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
R	PF22691	e5mg5R2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)
X	PF00108	e5mg5X1	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF00108	ECOD (1.6)
X	PF22691	e5mg5X2	A: a/b three-layered sandwiches	X: Thiolase-like (From Topology)	H: Thiolase-like (From Topology)	T: Thiolase-like	F: PF22691	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C, F, I, L, O C, F, I, L, O, R, U, X	PF00108	Thiolase, N-terminal domain (Thiolase_N)	Thiolase, N-terminal domain	Thiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also chalcone synthase.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D, G, J, M A, D, G, J, M, P, S, V	Hydroxymethylglutaryl-CoA synthase	-	-	-
B, E, H, K, N B, E, H, K, N, Q, T, W	2,4-diacetylphloroglucinol biosynthesis protein	-	-	-
C, F, I, L, O C, F, I, L, O, R, U, X	2,4-diacetylphloroglucinol biosynthesis protein PhlC	acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C, F, I, L, O C, F, I, L, O, R, U, X	IPR016039	Thiolase-like	Homologous Superfamily
C, F, I, L, O C, F, I, L, O, R, U, X	IPR020616	Thiolase, N-terminal	Domain
C, F, I, L, O C, F, I, L, O, R, U, X	IPR002155	Thiolase	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
C, F, I, L, O C, F, I, L, O, R, U, X	SCY	Parent Component: CYS RESID: AA0056 PSI-MOD : S-acetyl-L-cysteine MOD:00065