5M0J

Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth D]	SCOP2B Superfamily	RNA-binding protein She2p	8043992	3002016	SCOP2B (2022-06-29)
B [auth C]	SCOP2B Superfamily	RNA-binding protein She2p	8043992	3002016	SCOP2B (2022-06-29)
C [auth B]	SCOP2B Superfamily	RNA-binding protein She2p	8043992	3002016	SCOP2B (2022-06-29)
D [auth A]	SCOP2B Superfamily	RNA-binding protein She2p	8043992	3002016	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth D]	She2p	e5m0jD1	A: alpha arrays	X: L-aspartase middle domain-like	H: RNA-binding protein She2p (From Topology)	T: RNA-binding protein She2p	F: She2p	ECOD (1.6)
B [auth C]	She2p	e5m0jC1	A: alpha arrays	X: L-aspartase middle domain-like	H: RNA-binding protein She2p (From Topology)	T: RNA-binding protein She2p	F: She2p	ECOD (1.6)
C [auth B]	She2p	e5m0jB1	A: alpha arrays	X: L-aspartase middle domain-like	H: RNA-binding protein She2p (From Topology)	T: RNA-binding protein She2p	F: She2p	ECOD (1.6)
D [auth A]	She2p	e5m0jA1	A: alpha arrays	X: L-aspartase middle domain-like	H: RNA-binding protein She2p (From Topology)	T: RNA-binding protein She2p	F: She2p	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth D]	1.20.200.20	Mainly Alpha	Up-down Bundle	Fumarase C	Chain A, domain 2	CATH (4.3.0)
B [auth C]	1.20.200.20	Mainly Alpha	Up-down Bundle	Fumarase C	Chain A, domain 2	CATH (4.3.0)
C [auth B]	1.20.200.20	Mainly Alpha	Up-down Bundle	Fumarase C	Chain A, domain 2	CATH (4.3.0)
D [auth A]	1.20.200.20	Mainly Alpha	Up-down Bundle	Fumarase C	Chain A, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], F [auth G], G [auth H], H [auth I]	PF11435	RNA binding protein She2p (She2p)	RNA binding protein She2p	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], F [auth G], G [auth H], H [auth I]	SWI5-dependent HO expression protein 2,SWI5-dependent HO expression protein 3	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding lipid binding sequence-specific mRNA binding	localization cellular localization cellular macromolecule localization macromolecule localization intracellular mRNA localization cellular process RNA localization RNA transport nitrogen compound transport transport organic substance transport nucleic acid transport mRNA transport establishment of localization localization cellular localization cellular macromolecule localization macromolecule localization intracellular mRNA localization cellular process RNA localization RNA transport nitrogen compound transport transport organic substance transport nucleic acid transport mRNA transport establishment of localization establishment of RNA localization nucleobase-containing compound transport developmental process sex determination mating type determination reproductive process reproductive process in single-celled organism developmental process involved in reproduction mating type switching cellular component organization organelle organization organelle inheritance cellular component organization or biogenesis endoplasmic reticulum inheritance endoplasmic reticulum organization endomembrane system organization	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cellular bud cellular bud tip site of polarized growth membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle organelle subcompartment membrane intracellular anatomical structure cytoplasm cellular anatomical entity cytosol cellular bud cellular bud tip site of polarized growth membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle organelle subcompartment membrane endomembrane system endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum organelle membrane endoplasmic reticulum membrane
I [auth E], J [auth F]	ASH1 E3 (28 nt-loop)	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], F [auth G], G [auth H], H [auth I]	IPR036827	She2 domain superfamily	Homologous Superfamily
A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], F [auth G], G [auth H], H [auth I]	IPR024261	RNA binding protein She2	Domain
A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], A [auth D], B [auth C], C [auth B], D [auth A], E [auth J], F [auth G], G [auth H], H [auth I]	IPR031398	SWI5-dependent HO expression protein 3	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.