Annotations: 5M04

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01018	e5m04A2	A: beta complex topology	X: Obg GTP-binding protein N-terminal domain (From Topology)	H: Obg GTP-binding protein N-terminal domain (From Topology)	T: Obg GTP-binding protein N-terminal domain	F: PF01018	ECOD (1.6)
A	PF01926	e5m04A1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: PF01926	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.210.12	Mainly Beta	Distorted Sandwich	Spo0b-associated Gtp-binding Protein	Chain: A,	CATH (4.3.0)
A	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01018	GTP1/OBG (GTP1_OBG)	GTP1/OBG	The N-terminal domain of Swiss:P20964 has the OBG fold, which is formed by three glycine-rich regions inserted into a small 8-stranded beta-sandwich these regions form six left-handed collagen-like helices packed and H-bonded together.	Domain
A	PF01926	50S ribosome-binding GTPase (MMR_HSR1)	50S ribosome-binding GTPase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	GTPase ObgE/CgtA	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding DNA binding organic cyclic compound binding nucleic acid binding guanosine tetraphosphate binding guanyl nucleotide binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding DNA binding organic cyclic compound binding nucleic acid binding guanosine tetraphosphate binding guanyl nucleotide binding nucleotide binding guanyl ribonucleotide binding purine ribonucleotide binding nucleoside phosphate binding purine nucleotide binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding GDP binding ribonucleoprotein complex binding protein-containing complex binding ribosomal large subunit binding ribosome binding RNA binding rRNA binding GTP binding purine ribonucleoside triphosphate binding pyrophosphatase activity GTPase activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity	regulation of biological process ribonucleoprotein complex biogenesis regulation of cellular process biological regulation negative regulation of biological process regulation of ribosome biogenesis regulation of cellular component biogenesis cellular component biogenesis ribosome biogenesis negative regulation of cellular process negative regulation of ribosome biogenesis cellular process cellular component organization or biogenesis cell cycle regulation of biological process ribonucleoprotein complex biogenesis regulation of cellular process biological regulation negative regulation of biological process regulation of ribosome biogenesis regulation of cellular component biogenesis cellular component biogenesis ribosome biogenesis negative regulation of cellular process negative regulation of ribosome biogenesis cellular process cellular component organization or biogenesis cell cycle chromosome segregation cell cycle process developmental process dormancy process organelle assembly non-membrane-bounded organelle assembly cellular component organization organelle organization cellular component assembly ribosome assembly	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR031167	OBG-type guanine nucleotide-binding (G) domain	Domain
A	IPR045086	OBG-type GTPase	Family
A	IPR036726	GTP1/OBG domain superfamily	Homologous Superfamily
A	IPR014100	GTP-binding protein Obg/CgtA	Family
A	IPR006074	GTP1/OBG, conserved site	Conserved Site
A	IPR006169	GTP1/OBG domain	Domain
A	IPR006073	GTP binding domain	Domain
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.