Annotations: 5LZ6

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF13897	e5lz6A1	A: beta sandwiches	X: jelly-roll	H: Galactose-binding domain-like (From Topology)	T: Galactose-binding domain-like	F: PF13897	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.680	Mainly Beta	Sandwich	Jelly Rolls	GOLD domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF13897	Golgi-dynamics membrane-trafficking (GOLD_2)	Golgi-dynamics membrane-trafficking	Sec14-like Golgi-trafficking domain The GOLD domain is always found combined with lipid- or membrane-association domains [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Golgi resident protein GCP60	protein kinase A binding protein binding binding protein kinase A regulatory subunit binding amide binding adenyl ribonucleotide binding fatty-acyl-CoA binding nucleotide binding acyl-CoA binding purine ribonucleotide binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding protein kinase A binding protein binding binding protein kinase A regulatory subunit binding amide binding adenyl ribonucleotide binding fatty-acyl-CoA binding nucleotide binding acyl-CoA binding purine ribonucleotide binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding lipid binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding fatty acid derivative binding small molecule binding sulfur compound binding	steroid metabolic process lipid biosynthetic process primary metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process steroid biosynthetic process lipid metabolic process	membrane-bounded organelle intracellular organelle intracellular anatomical structure mitochondrion organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle membrane Golgi apparatus endomembrane system Golgi membrane bounding membrane of organelle organelle membrane
B	3A	5'-3' RNA polymerase activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA polymerase activity transferase activity RNA-dependent RNA polymerase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups cysteine-type peptidase activity peptidase activity catalytic activity, acting on a protein cysteine-type endopeptidase activity hydrolase activity 5'-3' RNA polymerase activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA polymerase activity transferase activity RNA-dependent RNA polymerase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups cysteine-type peptidase activity peptidase activity catalytic activity, acting on a protein cysteine-type endopeptidase activity hydrolase activity endopeptidase activity passive transmembrane transporter activity monoatomic ion channel activity channel activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity RNA binding binding organic cyclic compound binding nucleic acid binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding helicase activity RNA helicase activity ATP-dependent activity, acting on RNA ATP-dependent activity structural molecule activity	cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly cellular process cellular component organization or biogenesis cellular biosynthetic process cellular metabolic process RNA metabolic process viral life cycle primary metabolic process nucleobase-containing compound biosynthetic process cellular component organization cellular component biogenesis cellular component assembly protein-containing complex organization protein complex oligomerization protein-containing complex assembly cellular process cellular component organization or biogenesis cellular biosynthetic process cellular metabolic process RNA metabolic process viral life cycle primary metabolic process nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process nucleic acid biosynthetic process organic substance metabolic process viral genome replication biosynthetic process viral RNA genome replication organic cyclic compound biosynthetic process viral process organic substance biosynthetic process metabolic process macromolecule metabolic process gene expression DNA-templated transcription virion attachment to host cell biological process involved in interspecies interaction between organisms adhesion of symbiont to host cell adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host organonitrogen compound metabolic process proteolysis protein metabolic process	host intracellular membrane-bounded organelle host cellular component host intracellular part host cell membrane host cell cytoplasmic vesicle membrane cellular anatomical entity host cell cytoplasm part host intracellular organelle host cell cytoplasmic vesicle host cell cytoplasm host cell part host intracellular region membrane-bounded organelle intracellular anatomical structure host intracellular membrane-bounded organelle host cellular component host intracellular part host cell membrane host cell cytoplasmic vesicle membrane cellular anatomical entity host cell cytoplasm part host intracellular organelle host cell cytoplasmic vesicle host cell cytoplasm host cell part host intracellular region membrane-bounded organelle intracellular anatomical structure membrane intracellular vesicle intracellular membrane-bounded organelle intracellular organelle cytoplasmic vesicle membrane vesicle membrane cytoplasmic vesicle organelle cytoplasm vesicle organelle membrane viral capsid icosahedral viral capsid virion component T=pseudo3 icosahedral viral capsid

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR022408	Acyl-CoA-binding protein, ACBP, conserved site	Conserved Site
A	IPR000582	Acyl-CoA-binding protein, ACBP	Domain
A	IPR009038	GOLD domain	Domain
A	IPR014352	FERM/acyl-CoA-binding protein superfamily	Homologous Superfamily
A	IPR036598	GOLD domain superfamily	Homologous Superfamily
A	IPR035984	Acyl-CoA binding protein superfamily	Homologous Superfamily
B	IPR007053	LRAT domain	Domain
B	IPR001205	RNA-directed RNA polymerase, C-terminal domain	Domain
B	IPR043128	Reverse transcriptase/Diguanylate cyclase domain	Homologous Superfamily
B	IPR000199	Peptidase C3A/C3B, picornaviral	Domain
B	IPR001676	Picornavirus capsid	Domain
B	IPR014759	Helicase, superfamily 3, single-stranded RNA virus	Domain
B	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
B	IPR029053	Viral coat protein subunit	Homologous Superfamily
B	IPR009003	Peptidase S1, PA clan	Homologous Superfamily
B	IPR004004	Helicase/polymerase/peptidase polyprotein, Calicivirus-type	Family
B	IPR043502	DNA/RNA polymerase superfamily	Homologous Superfamily
B	IPR033703	Picornavirus/Calicivirus coat protein	Domain
B	IPR043504	Peptidase S1, PA clan, chymotrypsin-like fold	Homologous Superfamily
B	IPR007094	RNA-directed RNA polymerase, catalytic domain	Domain
B	IPR000605	Helicase, superfamily 3, single-stranded DNA/RNA virus	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: Q9H3P7	adrenal cortex carcinoma ductal breast carcinoma in situ pancreatic intraductal papillary-mucinous carcinoma plasma cell myeloma breast cancer osteosarcoma pancreatic intraductal papillary-mucinous neoplasm psoriasis dermatomyositis ovarian cancer pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia ulcerative colitis