Annotations: 5L6L

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF04014	e5l6lA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: PF04014	ECOD (1.6)
D	F_UNCLASSIFIED	e5l6lD1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: F_UNCLASSIFIED	ECOD (1.6)
E	PF04014	e5l6lE1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: PF04014	ECOD (1.6)
H	F_UNCLASSIFIED	e5l6lH1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: AbrB	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF01850	e5l6lB1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
C	PF01850	e5l6lC1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
F	PF01850	e5l6lF1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)
G	PF01850	e5l6lG1	A: a/b three-layered sandwiches	X: HAD domain-like	H: HAD domain-related	T: PIN domain-like	F: PF01850	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
C	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
F	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)
G	3.40.50.1010	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	5'-nuclease	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B, C, F, G	PF01850	PIN domain (PIN)	PIN domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D, E, H	VapB family protein	-	-	-
B, C, F, G	Ribonuclease VapC	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding nuclease activity hydrolase activity, acting on ester bonds catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity toxin activity	-	-
I [auth M]	DNA (27-MER)	-	-	-
J [auth N]	DNA (27-MER)	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D, E, H	IPR037914	SpoVT-AbrB domain superfamily	Homologous Superfamily
B, C, F, G	IPR002716	PIN domain	Domain
B, C, F, G	IPR029060	PIN-like domain superfamily	Homologous Superfamily
B, C, F, G	IPR022907	VapC family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.