5KVL

Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
B [auth L]d5kvll2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
B [auth L]d5kvll1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
A [auth H]d5kvlh1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
A [auth H]d5kvlh2 Artifacts Tags Tags Tags N-terminal Tags Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
B [auth L]PF07654e5kvlL1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07654ECOD (1.6)
B [auth L]PF07686e5kvlL2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)
A [auth H]PF07654e5kvlH2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07654ECOD (1.6)
A [auth H]PF07686e5kvlH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: PF07686ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B [auth L]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
A [auth H]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
B [auth L]Fab 10G4, anti-Leukotriene C4 L-KAPPA Humanized (humanized) IGKV1-16*01, IGKJ2*01, IGKJ2*02, IGKC*01 V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA IG FAB-GAMMA-1_KAPPA IMGT (202416-0)
A [auth H]Fab 10G4, anti-Leukotriene C4 VH-CH1 Humanized (humanized) IGHV4-59*01, IGHV4-59*08, IGHJ6*01, IGHG1*03, IGHG1*08, IGHG1*06 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-1_KAPPA IMGT (202416-0)