5KOD

Crystal Structure of GH3.5 Acyl Acid Amido Synthetase from Arabidopsis thaliana

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03321	e5kodA1	A: beta barrels	X: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	H: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	T: beta-barrel domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
A	PF03321	e5kodA2	A: a+b two layers	X: Alpha-lytic protease prodomain-like	H: a+b domain in acetyl-CoA synthetase-like proteins (From Topology)	T: a+b domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
A	PF03321	e5kodA3	A: a/b three-layered sandwiches	X: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	T: Rossmann-like domain in Acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
B	PF03321	e5kodB3	A: beta barrels	X: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	H: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	T: beta-barrel domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
B	PF03321	e5kodB1	A: a+b two layers	X: Alpha-lytic protease prodomain-like	H: a+b domain in acetyl-CoA synthetase-like proteins (From Topology)	T: a+b domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
B	PF03321	e5kodB2	A: a/b three-layered sandwiches	X: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	T: Rossmann-like domain in Acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
C	PF03321	e5kodC3	A: beta barrels	X: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	H: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	T: beta-barrel domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
C	PF03321	e5kodC1	A: a+b two layers	X: Alpha-lytic protease prodomain-like	H: a+b domain in acetyl-CoA synthetase-like proteins (From Topology)	T: a+b domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
C	PF03321	e5kodC2	A: a/b three-layered sandwiches	X: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	T: Rossmann-like domain in Acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
D	PF03321	e5kodD1	A: beta barrels	X: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	H: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)	T: beta-barrel domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
D	PF03321	e5kodD3	A: a+b two layers	X: Alpha-lytic protease prodomain-like	H: a+b domain in acetyl-CoA synthetase-like proteins (From Topology)	T: a+b domain in acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)
D	PF03321	e5kodD2	A: a/b three-layered sandwiches	X: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)	T: Rossmann-like domain in Acetyl-CoA synthetase-like proteins	F: PF03321	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF03321	GH3 auxin-responsive promoter (GH3)	GH3 auxin-responsive promoter	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Indole-3-acetic acid-amido synthetase GH3.5	acid-amino acid ligase activity indole-3-acetic acid amido synthetase activity catalytic activity ligase activity, forming carbon-nitrogen bonds ligase activity	regulation of cellular process organonitrogen compound biosynthetic process indole-containing compound metabolic process camalexin metabolic process positive regulation of secondary metabolite biosynthetic process positive regulation of metabolic process secondary metabolite biosynthetic process regulation of sulfur metabolic process indole-containing compound biosynthetic process positive regulation of camalexin biosynthetic process camalexin biosynthetic process organic substance biosynthetic process regulation of phytoalexin biosynthetic process sulfur compound metabolic process regulation of cellular process organonitrogen compound biosynthetic process indole-containing compound metabolic process camalexin metabolic process positive regulation of secondary metabolite biosynthetic process positive regulation of metabolic process secondary metabolite biosynthetic process regulation of sulfur metabolic process indole-containing compound biosynthetic process positive regulation of camalexin biosynthetic process camalexin biosynthetic process organic substance biosynthetic process regulation of phytoalexin biosynthetic process sulfur compound metabolic process phytoalexin metabolic process regulation of biological process cellular metabolic process regulation of cellular metabolic process organic cyclic compound metabolic process indole phytoalexin biosynthetic process sulfur compound biosynthetic process biosynthetic process positive regulation of phytoalexin metabolic process organic cyclic compound biosynthetic process regulation of camalexin biosynthetic process metabolic process toxin biosynthetic process regulation of metabolic process positive regulation of sulfur metabolic process cellular biosynthetic process positive regulation of biological process positive regulation of phytoalexin biosynthetic process positive regulation of cellular metabolic process secondary metabolic process organic substance metabolic process positive regulation of biosynthetic process positive regulation of cellular process toxin metabolic process regulation of biosynthetic process regulation of phytoalexin metabolic process organonitrogen compound metabolic process phytoalexin biosynthetic process biological regulation regulation of secondary metabolite biosynthetic process indole phytoalexin metabolic process regulation of cellular biosynthetic process regulation of secondary metabolic process cellular process positive regulation of cellular biosynthetic process response to auxin response to organic substance response to stimulus response to hormone response to chemical response to endogenous stimulus	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR004993	GH3 family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.