5KJB

Synechocystis apocarotenoid oxygenase (ACO) mutant - Glu150Asp

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5kjba_	All beta proteins	7-bladed beta-propeller	Retinal pigment epithelial membrane protein-like	RPE65-like	RPE65	(Synechocystis sp. PCC 6803 substr. Kazusa ) [TaxId: 1111708 ],	SCOPe (2.08)
B	d5kjbb_	All beta proteins	7-bladed beta-propeller	Retinal pigment epithelial membrane protein-like	RPE65-like	RPE65	(Synechocystis sp. PCC 6803 substr. Kazusa ) [TaxId: 1111708 ],	SCOPe (2.08)
C	d5kjbc_	All beta proteins	7-bladed beta-propeller	Retinal pigment epithelial membrane protein-like	RPE65-like	RPE65	(Synechocystis sp. PCC 6803 substr. Kazusa ) [TaxId: 1111708 ],	SCOPe (2.08)
D	d5kjbd_	All beta proteins	7-bladed beta-propeller	Retinal pigment epithelial membrane protein-like	RPE65-like	RPE65	(Synechocystis sp. PCC 6803 substr. Kazusa ) [TaxId: 1111708 ],	SCOPe (2.08)
E	d5kjbe_	All beta proteins	7-bladed beta-propeller	Retinal pigment epithelial membrane protein-like	RPE65-like	RPE65	(Synechocystis sp. PCC 6803 substr. Kazusa ) [TaxId: 1111708 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	RPE65-like	8092353	3002594	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	RPE65-like	8092353	3002594	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	RPE65-like	8092353	3002594	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	RPE65-like	8092353	3002594	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	RPE65-like	8092353	3002594	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	RPE65	e5kjbA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: RPE65	ECOD (1.6)
B	RPE65	e5kjbB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: RPE65	ECOD (1.6)
C	RPE65	e5kjbC1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: RPE65	ECOD (1.6)
D	RPE65	e5kjbD1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: RPE65	ECOD (1.6)
E	RPE65	e5kjbE1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: RPE65	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF03055	Retinal pigment epithelial membrane protein (RPE65)	Retinal pigment epithelial membrane protein	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	Apocarotenoid-15,15'-oxygenase	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen oxidoreductase activity carotenoid dioxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen catalytic activity dioxygenase activity cation binding ion binding binding metal ion binding small molecule binding all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity	isoprenoid catabolic process lipid catabolic process catabolic process carotene catabolic process hydrocarbon catabolic process cellular metabolic process terpene metabolic process primary metabolic process cellular lipid catabolic process hydrocarbon metabolic process carotene metabolic process cellular catabolic process organic substance metabolic process cellular lipid metabolic process isoprenoid catabolic process lipid catabolic process catabolic process carotene catabolic process hydrocarbon catabolic process cellular metabolic process terpene metabolic process primary metabolic process cellular lipid catabolic process hydrocarbon metabolic process carotene metabolic process cellular catabolic process organic substance metabolic process cellular lipid metabolic process metabolic process cellular process terpene catabolic process organic substance catabolic process isoprenoid metabolic process lipid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR004294	Carotenoid oxygenase	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.