5KDV
IMPa metallopeptidase from Pseudomonas aeruginosa
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | M60-like_N_1 | e5kdvA2 | A: beta sandwiches | X: jelly-roll | H: Jelly-roll domain in peptidase M60 family (From Topology) | T: Jelly-roll domain in peptidase M60 family | F: M60-like_N_1 | ECOD (1.6) |
A | EUF08039 | e5kdvA3 | A: alpha arrays | X: Immunomodulating metalloprotease IMPa helical domain (From Topology) | H: Immunomodulating metalloprotease IMPa helical domain (From Topology) | T: Immunomodulating metalloprotease IMPa helical domain | F: EUF08039 | ECOD (1.6) |
A | EUF08637 | e5kdvA1 | A: a/b three-layered sandwiches | X: Immunomodulating metalloprotease IMPa N-terminal domain (From Topology) | H: Immunomodulating metalloprotease IMPa N-terminal domain (From Topology) | T: Immunomodulating metalloprotease IMPa N-terminal domain | F: EUF08637 | ECOD (1.6) |
A | Peptidase_M60 | e5kdvA4 | A: mixed a+b and a/b | X: Zincin-like | H: Metalloproteases (zincins) catalytic domain (From Topology) | T: Metalloproteases (zincins) catalytic domain | F: Peptidase_M60 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF18642 | Immunomodulating metalloprotease helical domain (IMPa_helical) | Immunomodulating metalloprotease helical domain | IMPa is an immunomodulator metalloprotease that belongs to the peptidase M60 family Pfam:PF13402. This entry represents the helical domain found at the N-terminal of the Ig domain [1]. | Domain | |
PF18650 | Immunomodulating metalloprotease N-terminal domain (IMPa_N_2) | Immunomodulating metalloprotease N-terminal domain | PA0572 of P. aeruginosa is an inhibitor of PSGL-1, also known as an immunomodulating metalloprotease of P. aeruginosa (IMPa). IMPa prevents neutrophil extravasation and thereby protects P. aeruginosa from neutrophil attack [1]. It belongs to the pept ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR041549 | Immunomodulating metalloprotease helical domain | Domain | |
IPR031161 | Peptidase family M60 domain | Domain | |
IPR042279 | Peptidase M60, enhancin-like domain 3 | Homologous Superfamily | |
IPR040711 | Immunomodulating metalloprotease N-terminal domain | Domain |