Annotations: 5IBW

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00036	e5ibwA1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF00036	ECOD (1.6)
B	PF00036	e5ibwB1	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF00036	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)
B	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF13499	EF-hand domain pair (EF-hand_7)	EF-hand domain pair	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Calcium-binding EF-hand domain-containing protein	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding cytoskeletal protein binding protein binding myosin I binding myosin binding enzyme regulator activity molecular function regulator activity	-	-
C	Myosin IC heavy chain	cytoskeletal protein binding actin binding protein-containing complex binding protein binding binding actin filament binding myosin light chain binding myosin binding phospholipid binding lipid binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding cytoskeletal protein binding actin binding protein-containing complex binding protein binding binding actin filament binding myosin light chain binding myosin binding phospholipid binding lipid binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding microtubule binding tubulin binding cytoskeletal motor activity microfilament motor activity ATP-dependent activity	localization import into cell transport phagocytosis cellular process endocytosis establishment of localization vesicle-mediated transport cellular component organization organelle organization actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cytoskeleton organization localization import into cell transport phagocytosis cellular process endocytosis establishment of localization vesicle-mediated transport cellular component organization organelle organization actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cytoskeleton organization chemotaxis response to stimulus taxis response to chemical response to external stimulus locomotion cellular component biogenesis filopodium assembly cellular component assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cell projection assembly microtubule cytoskeleton organization mitotic cell cycle mitotic spindle organization mitotic cell cycle process microtubule-based process cell cycle microtubule cytoskeleton organization involved in mitosis spindle organization cell cycle process vesicle transport along actin filament vesicle cytoskeletal trafficking vesicle localization establishment of organelle localization cellular localization establishment of vesicle localization intracellular transport actin filament-based movement organelle localization establishment of localization in cell cytoskeleton-dependent intracellular transport actin filament-based transport cell motility actin filament organization supramolecular fiber organization pinocytosis	cell projection macropinocytic cup cellular anatomical entity plasma membrane bounded cell projection cell leading edge lamellipodium membrane-bounded organelle organelle vesicle intracellular organelle intracellular anatomical structure cytoskeleton intracellular non-membrane-bounded organelle actin cytoskeleton cell projection macropinocytic cup cellular anatomical entity plasma membrane bounded cell projection cell leading edge lamellipodium membrane-bounded organelle organelle vesicle intracellular organelle intracellular anatomical structure cytoskeleton intracellular non-membrane-bounded organelle actin cytoskeleton non-membrane-bounded organelle cytoplasm cytosol cell periphery plasma membrane membrane actin wave protein-containing complex myosin complex phagocytic cup phagocytic cup lip macropinocytic cup cytoskeleton cell cortex cortical cytoskeleton cortical actin cytoskeleton polymeric cytoskeletal fiber mitotic spindle spindle spindle microtubule mitotic spindle microtubule supramolecular fiber microtubule supramolecular polymer supramolecular complex microtubule cytoskeleton

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR002048	EF-hand domain	Domain
A, B	IPR011992	EF-hand domain pair	Homologous Superfamily
C	IPR036961	Kinesin motor domain superfamily	Homologous Superfamily
C	IPR036028	SH3-like domain superfamily	Homologous Superfamily
C	IPR010926	Class I myosin tail homology domain	Domain
C	IPR036072	Class I myosin, motor domain	Domain
C	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
C	IPR001609	Myosin head, motor domain	Domain
C	IPR001452	SH3 domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.