Annotations: 5H9D

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00348	e5h9dA1	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: PF00348	ECOD (1.6)
B	PF00348	e5h9dB1	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: PF00348	ECOD (1.6)
C	PF07307	e5h9dC1	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: PF07307	ECOD (1.6)
D	PF07307	e5h9dD1	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: PF07307	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.600.10	Mainly Alpha	Orthogonal Bundle	Farnesyl Diphosphate Synthase	Farnesyl Diphosphate Synthase	CATH (4.3.0)
B	1.10.600.10	Mainly Alpha	Orthogonal Bundle	Farnesyl Diphosphate Synthase	Farnesyl Diphosphate Synthase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00348	Polyprenyl synthetase (polyprenyl_synt)	Polyprenyl synthetase	-	Domain
C, D	PF07307	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 (HEPPP_synt_1)	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1	This family contains subunit 1 of heptaprenyl diphosphate synthase (HEPPP synthase) (EC:2.5.1.30) (approximately 230 residues long) from Bacilli. The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate ...	This family contains subunit 1 of heptaprenyl diphosphate synthase (HEPPP synthase) (EC:2.5.1.30) (approximately 230 residues long) from Bacilli. The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate synthesis [1]. This family corresponds to the regulatory subunit [2].	Domain
E [auth K], F [auth L]	PF07307	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 (HEPPP_synt_1)	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1	This family contains subunit 1 of heptaprenyl diphosphate synthase (HEPPP synthase) (EC:2.5.1.30) (approximately 230 residues long) from Bacilli. The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate ...	This family contains subunit 1 of heptaprenyl diphosphate synthase (HEPPP synthase) (EC:2.5.1.30) (approximately 230 residues long) from Bacilli. The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate synthesis [1]. This family corresponds to the regulatory subunit [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Farnesyl pyrophosphate synthetase	prenyltransferase activity transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups catalytic activity trans-hexaprenyltranstransferase activity	isoprenoid biosynthetic process cellular biosynthetic process cellular metabolic process lipid biosynthetic process primary metabolic process organic substance metabolic process biosynthetic process organic substance biosynthetic process cellular lipid metabolic process metabolic process cellular process lipid metabolic process isoprenoid metabolic process	-
C, D	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein	-	small molecule biosynthetic process cellular biosynthetic process cellular metabolic process cellular ketone metabolic process organic substance metabolic process biosynthetic process menaquinone metabolic process organic substance biosynthetic process small molecule metabolic process metabolic process cellular process menaquinone biosynthetic process ketone biosynthetic process	-
E [auth K], F [auth L]	C-terminal peptide from Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein	-	small molecule biosynthetic process cellular biosynthetic process cellular metabolic process cellular ketone metabolic process organic substance metabolic process biosynthetic process menaquinone metabolic process organic substance biosynthetic process small molecule metabolic process metabolic process cellular process menaquinone biosynthetic process ketone biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR000092	Polyprenyl synthetase	Family
A, B	IPR008949	Isoprenoid synthase domain superfamily	Homologous Superfamily
A, B	IPR033749	Polyprenyl synthetase, conserved site	Conserved Site
C, D	IPR009920	Heptaprenyl diphosphate synthase subunit 1	Family
E [auth K], F [auth L]	IPR009920	Heptaprenyl diphosphate synthase subunit 1	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.