Annotations: 5H1Q

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00876	e5h1qA1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
B	PF00876	e5h1qB1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
C	PF00876	e5h1qC1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
D	PF00876	e5h1qD1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
E	PF00876	e5h1qE1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
F	PF00876	e5h1qF1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
G	PF00876	e5h1qG1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)
H	PF00876	e5h1qH1	A: alpha bundles	X: Connexin 26 (From Topology)	H: Connexin 26 (From Topology)	T: Connexin 26	F: PF00876	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00876	Innexin (Innexin)	Innexin	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Innexin-6	wide pore channel activity passive transmembrane transporter activity channel activity transporter activity gap junction channel activity transmembrane transporter activity gap junction hemi-channel activity	transmembrane transport localization transport monoatomic ion transmembrane transport monoatomic ion transport cellular process establishment of localization	cell periphery plasma membrane membrane cellular anatomical entity cell-cell junction anchoring junction gap junction cell junction

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR000990	Innexin	Family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F, G, H	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F, G, H	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C, D, E A, B, C, D, E, F, G, H	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Channels: Gap Junctions and Related Channels	Innexin-6 gap junction channel

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.