5GUF

Structural insight into an intramembrane enzyme for archaeal membrane lipids biosynthesis

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF01864	e5gufA1	A: alpha duplicates or obligate multimers	X: Intramembrane CDP-DAG synthetase-related (From Homology)	H: Intramembrane CDP-DAG synthetase-related	T: Intramembrane CDP-archaeol synthase	F: PF01864	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01864	CDP-archaeol synthase (CarS-like)	CDP-archaeol synthase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CDP-archaeol synthase	cytidylyltransferase activity transferase activity CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups	glycerophospholipid biosynthetic process cellular biosynthetic process cellular metabolic process glycerophospholipid metabolic process lipid biosynthetic process primary metabolic process phospholipid biosynthetic process phospholipid metabolic process organic substance metabolic process biosynthetic process glycerolipid biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic substance biosynthetic process cellular lipid metabolic process glycerophospholipid biosynthetic process cellular biosynthetic process cellular metabolic process glycerophospholipid metabolic process lipid biosynthetic process primary metabolic process phospholipid biosynthetic process phospholipid metabolic process organic substance metabolic process biosynthetic process glycerolipid biosynthetic process organophosphate metabolic process organophosphate biosynthetic process organic substance biosynthetic process cellular lipid metabolic process phosphate-containing compound metabolic process metabolic process cellular process glycerolipid metabolic process phosphorus metabolic process lipid metabolic process	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR032690	CDP-archaeol synthase	Family
A	IPR002726	CDP-archaeol synthase, archaea	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Transmembrane	Alpha-helical polytopic	CTP transferase superfamily	CDP-archaeol synthase

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.