5FVK
Crystal structure of Vps4-Vfa1 complex from S.cerevisiae at 1.66 A resolution.
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d5fvka_ | All alpha proteins | Spectrin repeat-like | MIT domain | automated matches | automated matches | BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ], | SCOPe (2.08) |
B | d5fvkb_ | All alpha proteins | Spectrin repeat-like | MIT domain | automated matches | automated matches | BAKER'S YEAST (Saccharomyces cerevisiae ) [TaxId: 4932 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF04212 | e5fvkA1 | A: alpha bundles | X: Spectrin repeat-like | H: MIT domain (From Topology) | T: MIT domain | F: PF04212 | ECOD (1.6) |
B | PF04212 | e5fvkB1 | A: alpha bundles | X: Spectrin repeat-like | H: MIT domain (From Topology) | T: MIT domain | F: PF04212 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.20.58.80 | Mainly Alpha | Up-down Bundle | Methane Monooxygenase Hydroxylase | Chain G, domain 1 | CATH (4.3.0) |
B | 1.20.58.80 | Mainly Alpha | Up-down Bundle | Methane Monooxygenase Hydroxylase | Chain G, domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF04212 | MIT (microtubule interacting and transport) domain (MIT) | MIT (microtubule interacting and transport) domain | The MIT domain forms an asymmetric three-helix bundle [3] and binds ESCRT-III (endosomal sorting complexes required for transport) substrates [2]. | Domain | |
PF08432 | AAA-ATPase Vps4-associated protein 1 (Vfa1) | AAA-ATPase Vps4-associated protein 1 | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR003593 | AAA+ ATPase domain | Domain | |
IPR003959 | ATPase, AAA-type, core | Domain | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR007330 | MIT domain | Domain | |
IPR041569 | AAA ATPase, AAA+ lid domain | Domain | |
IPR015415 | Spastin/Vps4, C-terminal | Domain | |
IPR045253 | Vacuolar protein sorting-associated protein 4, MIT domain | Domain | |
IPR003960 | ATPase, AAA-type, conserved site | Conserved Site | |
IPR036181 | MIT domain superfamily | Homologous Superfamily | |
IPR013640 | VPS4-associated protein 1 | Family |