5FGN

Integral membrane protein lipooligosaccharide phosphoethanolamine transferase A (EptA) from Neisseria meningitidis

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	DUF1705	e5fgnA1	A: alpha bundles	X: Helical membrane domain in lipooligosaccharide phosphoethanolamine transferase A (From Topology)	H: Helical membrane domain in lipooligosaccharide phosphoethanolamine transferase A (From Topology)	T: Helical membrane domain in lipooligosaccharide phosphoethanolamine transferase A	F: DUF1705	ECOD (1.6)
A	Sulfatase_1	e5fgnA2	A: a/b three-layered sandwiches	X: Alkaline phosphatase-like (From Topology)	H: Alkaline phosphatase-like (From Topology)	T: Alkaline phosphatase-like	F: Sulfatase_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00884	Sulfatase (Sulfatase)	Sulfatase	-	Family
A	PF08019	Phosphoethanolamine transferase EptA/EptB (EptA_B_N)	Phosphoethanolamine transferase EptA/EptB	This entry represents a domain found in a group of bacterial phosphoethanolamine transferases, including eptA from Helicobacter pylori [1] and eptB from Escherichia coli EC:2.7.8.42 [2]. This domain is found immediately N-terminal to the sulphatase d ...	This entry represents a domain found in a group of bacterial phosphoethanolamine transferases, including eptA from Helicobacter pylori [1] and eptB from Escherichia coli EC:2.7.8.42 [2]. This domain is found immediately N-terminal to the sulphatase domain in many sulphatases.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	lipooligosaccharide phosphoethanolamine transferase A	transferase activity catalytic activity phosphotransferase activity, phosphate group as acceptor transferase activity, transferring phosphorus-containing groups cation binding ion binding binding metal ion binding small molecule binding	lipopolysaccharide biosynthetic process cellular biosynthetic process lipid biosynthetic process carbohydrate derivative metabolic process lipopolysaccharide metabolic process lipopolysaccharide core region biosynthetic process organic substance metabolic process polysaccharide metabolic process oligosaccharide biosynthetic process organic substance biosynthetic process carbohydrate derivative biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process lipopolysaccharide biosynthetic process cellular biosynthetic process lipid biosynthetic process carbohydrate derivative metabolic process lipopolysaccharide metabolic process lipopolysaccharide core region biosynthetic process organic substance metabolic process polysaccharide metabolic process oligosaccharide biosynthetic process organic substance biosynthetic process carbohydrate derivative biosynthetic process carbohydrate metabolic process polysaccharide biosynthetic process carbohydrate biosynthetic process oligosaccharide metabolic process cellular metabolic process liposaccharide metabolic process primary metabolic process lipopolysaccharide core region metabolic process macromolecule biosynthetic process biosynthetic process metabolic process cellular process macromolecule metabolic process lipid metabolic process	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR040423	Phosphoethanolamine transferase	Family
A	IPR012549	Phosphoethanolamine transferase, N-terminal	Domain
A	IPR000917	Sulfatase, N-terminal	Domain
A	IPR017850	Alkaline-phosphatase-like, core domain superfamily	Homologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM				Sulfatase

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Phospholipid Transferases	Lipid A phosphoethanolamine transferase

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.