Annotations: 5FCN

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], B [auth A]	Centrosomal protein of 135 kDa	cytoskeletal protein binding microtubule binding protein binding binding tubulin binding identical protein binding protein homodimerization activity protein dimerization activity	microtubule organizing center organization microtubule cytoskeleton organization centriole-centriole cohesion cellular component organization organelle organization centrosome cycle cellular process microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process protein localization regulation of localization microtubule organizing center organization microtubule cytoskeleton organization centriole-centriole cohesion cellular component organization organelle organization centrosome cycle cellular process microtubule-based process cell cycle cellular component organization or biogenesis cytoskeleton organization cell cycle process protein localization regulation of localization establishment of protein localization cellular localization regulation of biological process regulation of cellular process regulation of protein localization biological regulation positive regulation of biological process regulation of establishment of protein localization positive regulation of establishment of protein localization establishment of localization localization regulation of cellular localization cellular macromolecule localization macromolecule localization positive regulation of protein localization positive regulation of cellular process positive regulation of organelle organization regulation of cellular component organization positive regulation of cellular component organization cell projection organization plasma membrane bounded cell projection assembly cellular component biogenesis cellular component assembly positive regulation of non-motile cilium assembly cilium assembly positive regulation of cell projection organization cilium organization regulation of non-motile cilium assembly organelle assembly plasma membrane bounded cell projection organization positive regulation of cellular component biogenesis regulation of cell projection organization regulation of cell projection assembly regulation of cellular component biogenesis regulation of organelle organization regulation of plasma membrane bounded cell projection assembly positive regulation of cilium assembly regulation of cilium assembly regulation of organelle assembly non-motile cilium assembly cell projection assembly regulation of plasma membrane bounded cell projection organization positive regulation of plasma membrane bounded cell projection assembly positive regulation of organelle assembly centriole assembly non-membrane-bounded organelle assembly centrosome duplication centriole replication	intracellular organelle microtubule organizing center intracellular anatomical structure cytoskeleton organelle intracellular non-membrane-bounded organelle centriole cellular anatomical entity microtubule cytoskeleton non-membrane-bounded organelle cytoplasm cytosol centrosome

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A [auth B], B [auth A]	Pharos: Q66GS9	microcephaly 8, primary, autosomal recessive microcephaly intellectual disability ulcerative colitis atypical teratoid rhabdoid tumor glioblastoma malignant glioma ovarian cancer primitive neuroectodermal tumor spina bifida autosomal recessive primary microcephaly medulloblastoma nasopharyngeal carcinoma pilocytic astrocytoma psoriasis microcephaly 8, primary, autosomal recessive microcephaly intellectual disability ulcerative colitis atypical teratoid rhabdoid tumor glioblastoma malignant glioma ovarian cancer primitive neuroectodermal tumor spina bifida autosomal recessive primary microcephaly medulloblastoma nasopharyngeal carcinoma pilocytic astrocytoma psoriasis tuberculosis cervical cancer malignant ependymoma osteosarcoma Primary microcephaly Sjogren syndrome