5F5T

Crystal structure of the Prp38-MFAP1 complex of Chaetomium thermophilum

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5f5ta_	All alpha proteins	alpha-alpha superhelix	Pre-mRNA splicing factor Prp38 N-terminal-like	Pre-mRNA splicing factor Prp38-like	Pre-mRNA splicing factor Prp38A	(Thermochaetoides thermophila DSM 1495 ) [TaxId: 759272 ],	SCOPe (2.08)
B	d5f5tb_	All alpha proteins	alpha-alpha superhelix	Pre-mRNA splicing factor Prp38 N-terminal-like	Pre-mRNA splicing factor Prp38-like	Pre-mRNA splicing factor Prp38A	(Thermochaetoides thermophila DSM 1495 ) [TaxId: 759272 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PRP38-like	8051405	4007353	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PRP38-like	8055807	3002318	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	PRP38-like	8055807	3002318	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03371	e5f5tA1	A: alpha superhelices	X: Repetitive alpha hairpins	H: Pre-mRNA-splicing factor 38A (From Topology)	T: Pre-mRNA-splicing factor 38A	F: PF03371	ECOD (1.6)
B	PF03371	e5f5tB1	A: alpha superhelices	X: Repetitive alpha hairpins	H: Pre-mRNA-splicing factor 38A (From Topology)	T: Pre-mRNA-splicing factor 38A	F: PF03371	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C, D	PF06991	Microfibril-associated/Pre-mRNA processing (MFAP1)	Microfibril-associated/Pre-mRNA processing	-	Family
A, B	PF03371	PRP38 family (PRP38)	PRP38 family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
C, D	Putative uncharacterized protein	-	-	-
A, B	Putative uncharacterized protein	-	RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions RNA splicing cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process gene expression mRNA processing mRNA metabolic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process RNA splicing, via transesterification reactions mRNA splicing, via spliceosome organic substance biosynthetic process metabolic process cellular process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile macromolecule metabolic process RNA processing	membrane-bounded organelle protein-containing complex intracellular anatomical structure nucleus nuclear protein-containing complex intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle spliceosomal complex organelle ribonucleoprotein complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C, D	IPR033194	Microfibrillar-associated protein 1	Family
C, D	IPR009730	Micro-fibrillar-associated protein 1, C-terminal	Domain
A, B	IPR005037	Pre-mRNA-splicing factor 38	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.