Annotations: 5EZN

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF18638	e5eznA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF18638	ECOD (1.6)
C [auth B]	PF18638	e5eznB1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: PF18638	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF18638	Cysteine-Rich Protective Antigen 6 bladed domain (CyRPA)	Cysteine-Rich Protective Antigen 6 bladed domain	-	Repeat
B [auth E]	PF18638	Cysteine-Rich Protective Antigen 6 bladed domain (CyRPA)	Cysteine-Rich Protective Antigen 6 bladed domain	-	Repeat
C [auth B]	PF18638	Cysteine-Rich Protective Antigen 6 bladed domain (CyRPA)	Cysteine-Rich Protective Antigen 6 bladed domain	-	Repeat
D [auth G]	PF18638	Cysteine-Rich Protective Antigen 6 bladed domain (CyRPA)	Cysteine-Rich Protective Antigen 6 bladed domain	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Cysteine-rich protective antigen	-	biological process involved in interspecies interaction between organisms symbiont entry into host biological process involved in interaction with host biological process involved in symbiotic interaction	membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme apical part of cell apical complex membrane-enclosed lumen intracellular organelle lumen organelle lumen microneme lumen host cell plasma membrane host cellular component host cell part host cell membrane extracellular region protein-containing complex host extracellular space
B [auth E]	Cysteine-rich protective antigen	-	biological process involved in interspecies interaction between organisms symbiont entry into host biological process involved in interaction with host biological process involved in symbiotic interaction	membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme apical part of cell apical complex membrane-enclosed lumen intracellular organelle lumen organelle lumen microneme lumen host cell plasma membrane host cellular component host cell part host cell membrane extracellular region protein-containing complex host extracellular space
C [auth B]	Cysteine-rich protective antigen	-	biological process involved in interspecies interaction between organisms symbiont entry into host biological process involved in interaction with host biological process involved in symbiotic interaction	membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme apical part of cell apical complex membrane-enclosed lumen intracellular organelle lumen organelle lumen microneme lumen host cell plasma membrane host cellular component host cell part host cell membrane extracellular region protein-containing complex host extracellular space
D [auth G]	Cysteine-rich protective antigen	-	biological process involved in interspecies interaction between organisms symbiont entry into host biological process involved in interaction with host biological process involved in symbiotic interaction	membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme membrane-bounded organelle intracellular organelle intracellular anatomical structure cytoplasmic vesicle organelle intracellular vesicle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle vesicle cell periphery plasma membrane membrane microneme apical part of cell apical complex membrane-enclosed lumen intracellular organelle lumen organelle lumen microneme lumen host cell plasma membrane host cellular component host cell part host cell membrane extracellular region protein-containing complex host extracellular space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR041396	Cysteine-rich protective antigen 6 bladed domain	Domain
B [auth E]	IPR041396	Cysteine-rich protective antigen 6 bladed domain	Domain
C [auth B]	IPR041396	Cysteine-rich protective antigen 6 bladed domain	Domain
D [auth G]	IPR041396	Cysteine-rich protective antigen 6 bladed domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.