Annotations: 5EWN

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Astrovirus capsid protein P1 domain-like	8091689	3002535	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Positive stranded ssRNA viruses-like	8091687	3000918	SCOP2B (2022-06-29)
B	SCOP2 Family	Astrovirus VP-like	8051124	4007207	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Astrovirus capsid protein P1 domain-like	8091689	3002535	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Positive stranded ssRNA viruses-like	8091687	3000918	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	F_UNCLASSIFIED	e5ewnA2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Phage tail proteins	F: F_UNCLASSIFIED	ECOD (1.6)
A	PF03115	e5ewnA1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: PF03115	ECOD (1.6)
B	F_UNCLASSIFIED	e5ewnB2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Phage tail proteins	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF03115	e5ewnB1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: PF03115	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03115	Astrovirus capsid protein nucleoplasmin-like domain (Astro_capsid_N)	Astrovirus capsid protein nucleoplasmin-like domain	This product is encoded by astrovirus ORF2, one of the three astrovirus ORFs (1a, 1b, 2). The 87kD precursor protein undergoes an intracellular cleavage to form a 79kD protein. Subsequently, extracellular trypsin cleavage yields the three proteins fo ...	This product is encoded by astrovirus ORF2, one of the three astrovirus ORFs (1a, 1b, 2). The 87kD precursor protein undergoes an intracellular cleavage to form a 79kD protein. Subsequently, extracellular trypsin cleavage yields the three proteins forming the infectious virion [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Structural protein	-	import into cell receptor-mediated endocytosis of virus by host cell biological process involved in interspecies interaction between organisms transport viral life cycle establishment of localization vesicle-mediated transport biological process involved in interaction with host biological process involved in symbiotic interaction localization symbiont entry into host cell clathrin-dependent endocytosis viral process symbiont entry into host import into cell receptor-mediated endocytosis of virus by host cell biological process involved in interspecies interaction between organisms transport viral life cycle establishment of localization vesicle-mediated transport biological process involved in interaction with host biological process involved in symbiotic interaction localization symbiont entry into host cell clathrin-dependent endocytosis viral process symbiont entry into host cellular process clathrin-dependent endocytosis of virus by host cell receptor-mediated endocytosis endocytosis endocytosis involved in viral entry into host cell transport of virus	viral capsid T=3 icosahedral viral capsid icosahedral viral capsid virion component

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR004337	Astrovirus capsid protein, inner core domain	Domain
A, B	IPR029053	Viral coat protein subunit	Homologous Superfamily
A, B	IPR022027	Turkey astrovirus capsid protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.