5E8B

Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R126A

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	RNA polymerase-associated protein RTF1	DNA binding binding organic cyclic compound binding nucleic acid binding phosphoprotein binding basal transcription machinery binding RNA polymerase binding RNA polymerase II C-terminal domain binding enzyme binding RNA polymerase II C-terminal domain phosphoserine binding protein binding RNA polymerase II complex binding basal RNA polymerase II transcription machinery binding RNA polymerase core enzyme binding DNA binding binding organic cyclic compound binding nucleic acid binding phosphoprotein binding basal transcription machinery binding RNA polymerase binding RNA polymerase II C-terminal domain binding enzyme binding RNA polymerase II C-terminal domain phosphoserine binding protein binding RNA polymerase II complex binding basal RNA polymerase II transcription machinery binding RNA polymerase core enzyme binding phosphoserine residue binding protein phosphorylated amino acid binding RNA binding	cellular biosynthetic process mRNA 3'-end processing cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process mRNA processing mRNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process organic substance biosynthetic process cellular biosynthetic process mRNA 3'-end processing cellular metabolic process RNA metabolic process primary metabolic process gene expression macromolecule biosynthetic process mRNA processing mRNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process biosynthetic process organic substance biosynthetic process nucleic acid catabolic process RNA 3'-end processing metabolic process cellular process RNA processing macromolecule metabolic process sexual reproduction reproductive process meiotic cell cycle DNA metabolic process meiotic cell cycle process meiotic DNA double-strand break formation meiosis I cell cycle process cell cycle cell cycle process RNA biosynthetic process DNA-templated transcription nucleic acid biosynthetic process transcription by RNA polymerase II sno(s)RNA metabolic process sno(s)RNA transcription snoRNA transcription by RNA polymerase II nucleobase-containing compound biosynthetic process organic cyclic compound biosynthetic process ncRNA metabolic process sno(s)RNA processing sno(s)RNA 3'-end processing transcription elongation by RNA polymerase II DNA-templated transcription elongation regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process transcription elongation by RNA polymerase I positive regulation of metabolic process regulation of RNA metabolic process transcription by RNA polymerase I rRNA transcription positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of DNA-templated transcription elongation regulation of biological process positive regulation of nucleobase-containing compound metabolic process regulation of transcription by RNA polymerase I regulation of cellular metabolic process positive regulation of RNA metabolic process regulation of gene expression positive regulation of transcription elongation by RNA polymerase I regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of DNA-templated transcription, elongation positive regulation of biosynthetic process rRNA metabolic process positive regulation of transcription by RNA polymerase I positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process nucleolar large rRNA transcription by RNA polymerase I biological regulation regulation of macromolecule metabolic process regulation of cellular biosynthetic process regulation of transcription elongation by RNA polymerase I positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process DNA-templated transcription termination regulation of transcription by RNA polymerase II regulation of transcription elongation by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II cellular response to stimulus response to stimulus transcription-coupled nucleotide-excision repair regulation of cellular response to stress cellular response to stress nucleotide-excision repair response to stress regulation of response to stress DNA repair regulation of transcription-coupled nucleotide-excision repair regulation of DNA repair DNA damage response regulation of response to stimulus regulation of nucleotide-excision repair regulation of DNA metabolic process negative regulation of biological process negative regulation of cellular metabolic process negative regulation of RNA biosynthetic process negative regulation of nucleobase-containing compound metabolic process negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II negative regulation of metabolic process negative regulation of cellular biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of RNA metabolic process negative regulation of cellular process negative regulation of macromolecule metabolic process negative regulation of biosynthetic process global genome nucleotide-excision repair	protein-containing complex intracellular anatomical structure protein-DNA complex euchromatin chromatin chromosome cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle RNA polymerase II, holoenzyme transcription elongation factor complex protein-containing complex intracellular anatomical structure protein-DNA complex euchromatin chromatin chromosome cellular anatomical entity intracellular organelle organelle intracellular non-membrane-bounded organelle non-membrane-bounded organelle membrane-bounded organelle RNA polymerase II, holoenzyme transcription elongation factor complex nucleus membrane-enclosed lumen nuclear protein-containing complex transferase complex intracellular organelle lumen nucleoplasm catalytic complex intracellular membrane-bounded organelle Cdc73/Paf1 complex transferase complex, transferring phosphorus-containing groups nuclear DNA-directed RNA polymerase complex organelle lumen RNA polymerase complex DNA-directed RNA polymerase complex intracellular protein-containing complex nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036128	Plus3-like superfamily	Homologous Superfamily
A, B	IPR004343	Plus-3 domain	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.