5DTH

Crystal structure of MUPP1 PDZ8 domain from rattus norvegicus

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00595	e5dthA1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
B	PF00595	e5dthB1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
C	PF00595	e5dthC1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)
D	PF00595	e5dthD1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: PF00595	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
B	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
C	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
D	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00595	PDZ domain (PDZ)	PDZ domain	PDZ domains are found in diverse signaling proteins.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Multiple PDZ domain protein	-	regulation of cytoskeleton organization regulation of biological process regulation of cellular component organization regulation of cellular process microtubule cytoskeleton organization biological regulation regulation of microtubule-based process regulation of organelle organization cellular component organization organelle organization cellular process microtubule-based process cellular component organization or biogenesis regulation of microtubule cytoskeleton organization regulation of cytoskeleton organization regulation of biological process regulation of cellular component organization regulation of cellular process microtubule cytoskeleton organization biological regulation regulation of microtubule-based process regulation of organelle organization cellular component organization organelle organization cellular process microtubule-based process cellular component organization or biogenesis regulation of microtubule cytoskeleton organization cytoskeleton organization protein localization cellular localization establishment of protein localization nitrogen compound transport transport organic substance transport intracellular transport establishment of localization localization protein transport establishment of localization in cell cellular macromolecule localization macromolecule localization intracellular protein transport microtubule organizing center organization developmental process multicellular organismal process plasma membrane bounded cell projection organization cellular developmental process cell projection organization cell development neuron projection development nervous system development generation of neurons neurogenesis multicellular organism development neuron differentiation dendrite development cell differentiation neuron development anatomical structure development system development tight junction organization cellular component biogenesis cell junction organization cellular component assembly tight junction assembly cell junction assembly cell-cell junction assembly cell-cell junction organization cell adhesion myelination axon ensheathment ensheathment of neurons cellular response to stimulus response to stimulus signaling signal transduction intracellular signal transduction cell communication	cellular anatomical entity endomembrane system apical part of cell cell periphery membrane plasma membrane plasma membrane region apical plasma membrane cell-cell junction protein-containing complex plasma membrane protein complex anchoring junction membrane protein complex apical junction complex cellular anatomical entity endomembrane system apical part of cell cell periphery membrane plasma membrane plasma membrane region apical plasma membrane cell-cell junction protein-containing complex plasma membrane protein complex anchoring junction membrane protein complex apical junction complex cell junction subapical complex somatodendritic compartment cell projection dendrite dendritic tree neuron projection plasma membrane bounded cell projection intracellular anatomical structure cytoplasm apicolateral plasma membrane synapse glutamatergic synapse membrane-bounded organelle intracellular organelle cytoplasmic vesicle organelle intracellular vesicle intracellular membrane-bounded organelle vesicle compact myelin myelin sheath Schmidt-Lanterman incisure postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization asymmetric synapse bicellular tight junction tight junction

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR004172	L27 domain	Domain
A, B, C, D	IPR036034	PDZ superfamily	Homologous Superfamily
A, B, C, D	IPR036892	L27 domain superfamily	Homologous Superfamily
A, B, C, D	IPR032078	Multiple PDZ domain protein, unstructured region	Domain
A, B, C, D	IPR001478	PDZ domain	Domain
A, B, C, D	IPR015132	L27-2	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.