Annotations: 5DOO

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PqqD-like	8090237	4005476	SCOP2 (2022-06-29)
A	SCOP2 Family	PqqD-like	8090238	4005476	SCOP2 (2022-06-29)
A	SCOP2 Family	PKMT methyltransferase domain-like	8051526	4007420	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Winged helix DNA-binding domain	8090241	3000034	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Winged helix DNA-binding domain	8090242	3000034	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	S-adenosyl-L-methionine-dependent methyltransferases	8090235	3000118	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Winged helix DNA-binding domain	8090241	3000034	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	S-adenosyl-L-methionine-dependent methyltransferases	8090235	3000118	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Winged helix DNA-binding domain	8090242	3000034	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	COG4797_1st	e5dooA1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: COG4797_1st	ECOD (1.6)
A	COG4797_2nd	e5dooA2	A: alpha arrays	X: HTH	H: HTH	T: winged	F: COG4797_2nd	ECOD (1.6)
A	Methyltransf_11_2	e5dooA3	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: Methyltransf_11_2	ECOD (1.6)
B	COG4797_1st	e5dooB2	A: alpha arrays	X: HTH	H: HTH	T: winged	F: COG4797_1st	ECOD (1.6)
B	COG4797_2nd	e5dooB3	A: alpha arrays	X: HTH	H: HTH	T: winged	F: COG4797_2nd	ECOD (1.6)
B	Methyltransf_11_2	e5dooB1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: S-adenosyl-L-methionine-dependent methyltransferases	F: Methyltransf_11_2	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF21782	PKMT, C-terminal winged helix domain (PKMT_2nd)	PKMT, C-terminal winged helix domain	This entry represents the C-terminal winged helix domain of PKMTs. PKMTs are protein-lysine methyltransferases that catalyze the methylation of lysine residues on many different proteins. They consist of N-terminal S-adenosylmethionine binding domain ...	This entry represents the C-terminal winged helix domain of PKMTs. PKMTs are protein-lysine methyltransferases that catalyze the methylation of lysine residues on many different proteins. They consist of N-terminal S-adenosylmethionine binding domain, a middle domain and a C-terminal domain. The middle and the C-terminal domain share significant structural similarity and are both distantly related to HTH winged helix DNA-binding domains.	Domain
A, B	PF13847	Methyltransferase domain (Methyltransf_31)	Methyltransferase domain	This family appears to have methyltransferase activity.	Domain
A, B	PF10119	Predicted methyltransferase regulatory domain (MethyTransf_Reg)	Predicted methyltransferase regulatory domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	protein lysine methyltransferase 2	cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR025714	Methyltransferase domain	Domain
A, B	IPR048976	PKMT, C-terminal winged helix domain	Domain
A, B	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily	Homologous Superfamily
A, B	IPR018773	Methyltransferase regulatory domain, predicted	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.