5CXK

Crystal structure of beta carbonic anhydrase from Vibrio cholerae

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5cxka_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
B	d5cxkb_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
C [auth H]	d5cxkh_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
D [auth G]	d5cxkg_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
E [auth D]	d5cxkd_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
F [auth C]	d5cxkc_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
G [auth F]	d5cxkf_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)
H [auth E]	d5cxke_	Alpha and beta proteins (a/b)	Resolvase-like	beta-carbonic anhydrase, cab	beta-carbonic anhydrase, cab	automated matches	(Vibrio cholerae ) [TaxId: 666 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	beta-carbonic anhydrase cab	8082596	4000510	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)
C [auth H]	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)
E [auth D]	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)
F [auth C]	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)
G [auth F]	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)
H [auth E]	SCOP2B Superfamily	beta-carbonic anhydrase cab	8082597	3000468	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00484	e5cxkA1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
B	PF00484	e5cxkB1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
C [auth H]	PF00484	e5cxkH1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
D [auth G]	PF00484	e5cxkG1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
E [auth D]	PF00484	e5cxkD1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
F [auth C]	PF00484	e5cxkC1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
G [auth F]	PF00484	e5cxkF1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)
H [auth E]	PF00484	e5cxkE1	A: a/b three-layered sandwiches	X: beta-carbonic anhydrase-like	H: beta-carbonic anhydrase (From Topology)	T: beta-carbonic anhydrase	F: PF00484	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
B	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
C [auth H]	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
D [auth G]	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
E [auth D]	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
F [auth C]	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
G [auth F]	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)
H [auth E]	3.40.1050.10	Alpha Beta	3-Layer(aba) Sandwich	Beta-carbonic Anhydrase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth H], D [auth G], E [auth D], A, B, C [auth H], D [auth G], E [auth D], F [auth C], G [auth F], H [auth E]	PF00484	Carbonic anhydrase (Pro_CA)	Carbonic anhydrase	This family includes carbonic anhydrases as well as a family of non-functional homologues related to YbcF.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth H], D [auth G], E [auth D], A, B, C [auth H], D [auth G], E [auth D], F [auth C], G [auth F], H [auth E]	Carbonic anhydrase	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding carbonate dehydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity	carbon utilization response to nutrient levels response to stimulus	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth H], D [auth G], E [auth D], A, B, C [auth H], D [auth G], E [auth D], F [auth C], G [auth F], H [auth E]	IPR001765	Carbonic anhydrase	Family
A, B, C [auth H], D [auth G], E [auth D], A, B, C [auth H], D [auth G], E [auth D], F [auth C], G [auth F], H [auth E]	IPR015892	Carbonic anhydrase, prokaryotic-like, conserved site	Conserved Site
A, B, C [auth H], D [auth G], E [auth D], A, B, C [auth H], D [auth G], E [auth D], F [auth C], G [auth F], H [auth E]	IPR036874	Carbonic anhydrase superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.