5BQ2

Crystal structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (UDP-N-acetylglucosamine enolpyruvyl transferase, EPT) from Pseudomonas aeruginosa

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5bq2a1	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	automated matches	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
A	d5bq2a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
B	d5bq2b1	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	automated matches	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
B	d5bq2b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
C	d5bq2c1	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	automated matches	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
C	d5bq2c2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
D	d5bq2d1	Alpha and beta proteins (a+b)	IF3-like	EPT/RTPC-like	Enolpyruvate transferase, EPT	automated matches	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)
D	d5bq2d2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Pseudomonas aeruginosa PAO1 ) [TaxId: 208964 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Enolpyruvate transferase EPT	8074859	4001425	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	EPT/RTPC-like	8074860	3001530	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	EPT/RTPC-like	8074860	3001530	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	EPT/RTPC-like	8074860	3001530	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	EPT/RTPC-like	8074860	3001530	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00275	e5bq2A2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: PF00275	ECOD (1.6)
B	PF00275	e5bq2B1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: PF00275	ECOD (1.6)
C	PF00275	e5bq2C2	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: PF00275	ECOD (1.6)
D	PF00275	e5bq2D1	A: a+b two layers	X: IF3-like	H: EPT/RTPC-like (From Topology)	T: EPT/RTPC-like	F: PF00275	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
B	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
C	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)
D	3.65.10.10	Alpha Beta	Alpha-beta prism	UDP-n-acetylglucosamine1-carboxyvinyl-transferase	Chain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00275	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) (EPSP_synthase)	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups catalytic activity	developmental process regulation of biological process regulation of developmental process biological regulation regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis cellular process cell cycle cellular biosynthetic process developmental process regulation of biological process regulation of developmental process biological regulation regulation of cell shape cell morphogenesis regulation of cell morphogenesis anatomical structure morphogenesis anatomical structure development regulation of biological quality regulation of anatomical structure morphogenesis cellular process cell cycle cellular biosynthetic process cell wall organization or biogenesis glycosaminoglycan metabolic process organonitrogen compound biosynthetic process carbohydrate derivative metabolic process cellular component biogenesis organic substance metabolic process peptidoglycan metabolic process organic substance biosynthetic process glycosaminoglycan biosynthetic process cellular component organization or biogenesis carbohydrate derivative biosynthetic process peptidoglycan-based cell wall biogenesis organonitrogen compound metabolic process cellular metabolic process macromolecule biosynthetic process peptidoglycan biosynthetic process cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process aminoglycan metabolic process aminoglycan biosynthetic process metabolic process macromolecule metabolic process amino sugar biosynthetic process nucleotide-sugar metabolic process primary metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process UDP-N-acetylgalactosamine biosynthetic process UDP-N-acetylgalactosamine metabolic process nucleobase-containing small molecule metabolic process organic cyclic compound biosynthetic process amino sugar metabolic process small molecule metabolic process phosphorus metabolic process nucleotide-sugar biosynthetic process cell division cellular component organization cell wall organization external encapsulating structure organization	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR001986	Enolpyruvate transferase domain	Domain
A, B, C, D	IPR005750	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Family
A, B, C, D	IPR013792	RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta	Homologous Superfamily
A, B, C, D	IPR036968	Enolpyruvate transferase domain superfamily	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B, C, D	QPA	Parent Component: CYS RESID: AA0391 PSI-MOD : 2-(S-L-cysteinyl)pyruvic acid O-phosphothioketal MOD:00797

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.