5AF1

Crystal structure of Candida albicans Mep2

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Ammonium transporter	8082995	3001978	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Ammonium transporter	8082995	3001978	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00909	e5af1A1	A: alpha complex topology	X: Ammonium transporter-related (From Homology)	H: Ammonium transporter-related	T: Ammonium transporter	F: PF00909	ECOD (1.6)
B	PF00909	e5af1B1	A: alpha complex topology	X: Ammonium transporter-related (From Homology)	H: Ammonium transporter-related	T: Ammonium transporter	F: PF00909	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.3430.10	Mainly Alpha	Orthogonal Bundle	Ammonium transporter fold	Ammonium transporter AmtB like domains	CATH (4.3.0)
B	1.10.3430.10	Mainly Alpha	Orthogonal Bundle	Ammonium transporter fold	Ammonium transporter AmtB like domains	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00909	Ammonium Transporter Family (Ammonium_transp)	Ammonium Transporter Family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	MEP2	passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity channel activity transporter activity transmembrane transporter activity ammonium transmembrane transporter activity	transmembrane transport localization nitrogen compound transport transport ammonium transmembrane transport cellular process inorganic ion transmembrane transport establishment of localization inorganic cation transmembrane transport cellular response to stimulus cellular response to nutrient levels response to nutrient levels response to stimulus cellular response to stress transmembrane transport localization nitrogen compound transport transport ammonium transmembrane transport cellular process inorganic ion transmembrane transport establishment of localization inorganic cation transmembrane transport cellular response to stimulus cellular response to nutrient levels response to nutrient levels response to stimulus cellular response to stress response to stress response to starvation cellular response to starvation growth filamentous growth of a population of unicellular organisms in response to starvation filamentous growth filamentous growth of a population of unicellular organisms cellular response to nitrogen levels cellular response to nitrogen starvation	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR018047	Ammonium transporter, conserved site	Conserved Site
A, B	IPR029020	Ammonium/urea transporter	Homologous Superfamily
A, B	IPR001905	Ammonium transporter	Family
A, B	IPR024041	Ammonium transporter AmtB-like domain	Domain

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B	OPM	Transmembrane	Alpha-helical polytopic	Ammonia/urea transporters/Na+ exporter	Ammonia transporter Amt

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Channels: Amt/Mep/Rh proteins	Mep2 ammonium transceptor (R3)

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.